Iowa State vs TCU Prediction and Pick, Week 11

Iowa State vs TCU Prediction and Pick, Week 11. Place a bet on this CFB football game with the best odds.

Iowa State vs TCU Prediction: Trends

• Over the past six games, Iowa State has a record of 1-5 against the spread.
• In its previous five games, Iowa State has a record of 1-4 against the spread.
• After eight games versus Texas Christian, Iowa State has a record of 6-2 against the spread.
• Iowa State has a winning record of 4-1 against Texas Christian in its last five games.
• In its previous five games played away from home, Iowa State has a record of 0-5 against the spread.
• In the last seven games that Iowa State has played on the road versus Texas Christian, the team has a record of 2-5 all-time.
• In their previous five games against opponents from the Big 12 conference, Iowa State has a record of 1-4 against the spread.
• Among the twenty games that Iowa State has played in November, the total has been UNDER in thirteen of those contests.
• Out of the five games that Iowa State has played in week 11, the total has been over in four of those games.
• Over the past 12 games, Texas Christian has a record of 8-4 against the spread.
• There have been four of Texas Christian’s last six games in which the total has been UNDER.
• Texas Christian has a winning record of 10-2 in its previous 12 games.
• In each of Texas Christian’s last five games versus Iowa State, the total has been over in four of those games.
• In its last seven games played at home, Texas Christian has a perfect record of seven wins and zero losses.
• When playing at home versus Iowa State, Texas Christian has a winning record of 4-1 single-score in its last five games.
• After seven games played in November, Texas Christian has a record of 5-2 against the spread.
• Out of the five games that Texas Christian has played in week 11, the total has been under in four of those games.
• In its previous ten games played on a Saturday, Texas Christian has a record of 7-3 against the spread.

Iowa State vs TCU Prediction

Now we have the Iowa State vs TCU Prediction for both teams.

This Week 11 matchup between Iowa State and TCU brings plenty of storyline intrigue, especially given the contrasting performances of these teams in recent trends and their history against each other. Iowa State has dominated the head-to-head series recently, going 6-2 against the spread in the last eight meetings and winning four of the last five outright. However, the Cyclones have been a completely different team on the road this year, where they have struggled significantly, posting an 0-5 record against the spread in their last five road contests and going just 2-5 all-time in their last seven road trips to Fort Worth. Meanwhile, TCU has been extremely reliable at home, winning seven straight games in their own stadium and holding a 10-2 overall record in their last 12 matchups. Trends also point to some scoring variance, as Iowa State tends to hit the UNDER in November, but TCU matchups with the Cyclones often push toward the OVER. This sets the stage for a fascinating chess match: a balanced but inconsistent Iowa State offense against a TCU team that thrives at home and has been more productive offensively in recent weeks. Momentum, home comfort, and matchup familiarity are all keys here.

For Iowa State, the challenge is consistency and finishing games. The Cyclones have shown they can move the ball efficiently at times, ranking in the middle of the pack nationally in both rushing and passing production. They do a solid job controlling possession with 31 minutes of average time of field, and their offense averages just under 6 yards per play, signaling a balanced approach. The rushing attack sits around 164 yards per game, allowing Iowa State to establish tempo, while the passing game provides enough explosiveness to stretch defenses. However, the issues arise in the fourth quarter, where Iowa State scoring drops significantly to just 5 points per game, one of the lowest marks in FBS. Combine that with their road struggles, high turnover vulnerability, and an inability to sustain scoring bursts past halftime, and the Cyclones find themselves constantly in tight late-game scenarios they haven’t been able to finish on the road. The defense remains capable, but they will need to create pressure—something they have not consistently done this season.

On the TCU side, the Horned Frogs are playing with confidence, especially at home where they’ve won seven straight. Their offense has been the driving force, averaging over 34 points per game and moving the ball effectively through the air at more than 300 passing yards per contest. The passing attack has been explosive and efficient, ranking top-15 nationally, and the team does an excellent job adjusting after halftime, shown in strong third and fourth quarter scoring numbers. Where TCU has struggled is running the football, averaging just 124 yards per game, but against an Iowa State defense allowing 4.63 yards per carry, this could be a get-right opportunity. The Horned Frogs also play disciplined late in games and at home—a key factor in a matchup that historically features tight margins in Fort Worth. Defensively, TCU bends but doesn’t break often, and if they can prevent Iowa State from controlling the clock, they can dictate pace early and force the Cyclones into passing situations where mistakes become more likely.

✅ Our CFB Week 11 Pick: TCU

Iowa State vs TCU Prediction: Head to Head

Iowa State vs TCU Prediction: Iowa State Last 10 Games

Iowa State vs TCU Prediction: TCU Last 10 Games

Iowa State vs TCU Prediction: Iowa State Offense

Iowa State vs TCU Prediction: TCU Offense

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