Chargers vs Jaguars Prediction and Pick, Week 11

The Chargers and Jaguars are set to meet again in a matchup that brings back memories of their unforgettable 2023 playoff battle, when Jacksonville pulled off one of the biggest comebacks in postseason history to stun Los Angeles 31-30. Fast forward to Week 11 of the 2025 NFL season, and both teams come in looking to solidify their playoff positioning with plenty at stake. The Chargers have been one of the AFC’s most inconsistent teams, capable of beating anyone but also susceptible to letdowns, while the Jaguars continue to show flashes of brilliance behind Trevor Lawrence and a defense that’s made timely stops. These two teams have met several times in recent years, and the series has swung back and forth — though Jacksonville has had the upper hand lately, winning three of the last five. The matchup pits the Chargers’ high-powered offense against a Jaguars team that thrives on forcing mistakes and controlling tempo, making this an intriguing chess match of styles. As both squads fight to stay within striking distance in their respective divisions, this game could very well serve as a tiebreaker-type win for postseason implications.

The Los Angeles Chargers enter this game riding momentum from back-to-back victories over Minnesota and Tennessee, showing a more balanced attack and sharper game management from Justin Herbert. Their offense ranks among the top ten in efficiency metrics, averaging 23.5 points per game and over 255 passing yards per contest, good for 4th in the NFL. The Chargers’ offensive line has provided improved protection recently, allowing Herbert to take advantage of downfield opportunities while establishing a steady run game behind their 123 rushing yards per game average. Where Los Angeles truly excels is in time of possession — ranking 2nd in the league at 33 minutes per game — and total plays per drive, showing they can dictate pace and wear defenses down. Still, turnovers remain a concern, as they average nearly 1.5 giveaways per game, something the opportunistic Jaguars defense will look to exploit. Defensively, the Chargers have quietly been one of the better units in the AFC, ranking 6th against the pass and top 12 in scoring defense. If Herbert remains sharp and the defense continues to limit explosive plays, Los Angeles has the firepower and control to win a tough road battle.

Jacksonville, meanwhile, remains a tough out, especially at home, where Trevor Lawrence has consistently elevated his play. The Jaguars have won five of their last seven and are 3-1 against teams currently above .500, showing they rise to the occasion in big games. Their offense, while not as explosive as Los Angeles’, is methodical and efficient, averaging over 65 plays per game (3rd in the league) and nearly 120 rushing yards per contest. Travis Etienne continues to be a focal point, both as a rusher and receiver, while Lawrence’s command in short-to-intermediate passing keeps defenses honest. Defensively, Jacksonville’s front seven has been dominant against the run — allowing just 91 yards per game — and consistently forces teams into long passing downs. They’ve been opportunistic as well, forcing two turnovers per game, ranking among the top five in takeaways. However, their secondary has been vulnerable, giving up 245 passing yards per game (27th), which could spell trouble against Herbert’s deep threats. For the Jaguars to win, they’ll need to pressure the quarterback and control the pace through the run game, minimizing Herbert’s time on the field.

✅ Our Chargers vs Jaguars Pick: CHARGERS

Chargers vs Jaguars Prediction: Head to Head

Date	Opponent	Score	Spread	Total	Moneyline
1/14/23	@JAC	JAC 31-30	JAC+2.5	O47	JAC+110
9/25/22	@LAC	JAC 38-10	LAC-10.0	U50.5	LAC-630
10/25/20	@LAC	LAC 39-29	LAC-7.5	O49.5	LAC-385
12/08/19	@JAC	LAC 45-10	JAC+3.5	O41.5	JAC+155
11/12/17	@JAC	JAC 20-17	NL	NL	NL

Date	Opponent	Score	Spread	Total	Moneyline
11/02/25	@LV	W 30-29	W+1.5	O45.5	WEVEN
10/19/25	LAR	L 35-7	L+4.5	U47.5	L+176
10/12/25	SEA	L 20-12	L-1.5	U46.5	L-122
10/06/25	KC	W 31-28	W+4.5	O47.5	W+180
9/28/25	@SF	W 26-21	W+3.5	U48.5	W+119
9/21/25	HOU	W 17-10	W-1.5	U46.5	W-127
9/14/25	@CIN	L 31-27	W+5.5	O49.5	L+198
9/07/25	CAR	W 26-10	W-2.5	U46.5	W-161
1/05/25	@IND	L 26-23	L+1.5	O46.5	L+102
12/29/24	TEN	W 20-13	W-4.0	U46	W-192

Chargers vs Jaguars Prediction: LA Offense

Chargers vs Jaguars Prediction: Jacksonville Offense

Chargers vs Jaguars Prediction and Pick, Week 11, by YouWager.lv.