Titans vs Cardinals Betting Prediction and Pick Week 5, 2025
Titans vs Cardinals Betting Prediction and Pick Week 5, 2025. Place a bet on this NFL football game with the best odds.
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The Tennessee Titans vs. Arizona Cardinals Week 5 matchup offers one of the clearer contrasts of the NFL slate.
Titans vs Cardinals Betting Prediction
Now we have the Titans vs Cardinals Betting Prediction for both teams, but first, the head to head stats:
From a betting perspective, this matchup heavily favors Arizona. Tennessee’s trends — 0-10 in their last ten games, 0-5 against the spread versus Arizona, and poor road performances — make it difficult to back them with any confidence. Arizona’s ability to control tempo, protect home field, and exploit Tennessee’s defensive weaknesses gives them a clear edge. While both teams have had stretches of inconsistency, the Cardinals are stronger statistically, historically, and situationally in this matchup. If Tennessee fails to generate turnovers or control the clock early, this game could get away from them quickly.
Titans vs Cardinals Betting Prediction: Head to Head
| Date | Team | Opp | Close | Result | ATS/OU |
|---|---|---|---|---|---|
| Aug 27, 2022 | Cardinals | @Titans | +3 / 34.5 | Lost 23-26 | Push / Over |
| Sep 12, 2021 | Cardinals | @Titans | +2.5 / 54 | Won 38-13 | Won / Under |
| Dec 10, 2017 | Cardinals | Titans | +2.5 / 42 | Won 12-7 | Won / Under |
| Dec 15, 2013 | Cardinals | Titans | +3 / 43 | Lost 0-0 | Won / Under |
| Aug 23, 2012 | Cardinals | Titans | -3 / 40.5 | Lost 0-0 | Lost / Under |
| Aug 23, 2010 | Cardinals | Titans | -3.5 / 37.5 | Lost 0-0 | Lost / Under |
| Nov 29, 2009 | Cardinals | Titans | -3.5 / 44 | Lost 0-0 | Lost / Under |
| Oct 23, 2005 | Cardinals | @Titans | +5.5 / 44.5 | Lost 0-0 | Won / Under |
Titans vs Cardinals Betting Prediction: Tennessee
Tennessee has been in complete freefall, dropping ten straight games while failing to find consistency on either side of the ball. Their offense ranks near the bottom of the league, averaging just 17 points per game with almost no explosive capability. The passing game has been ineffective, the offensive line has been a liability, and penalties have routinely stalled drives. With only one road win in their last several attempts, Tennessee faces an uphill battle entering Arizona’s stadium.
Titans vs Cardinals Betting Prediction: Tennessee Trends
- Over the past ten games, Tennessee has a record of 1-9 against the spread.
- Tennessee has a losing record of 0-10 in its last ten games.
- In its last five games against Arizona, Tennessee has a record of 0-5 against the spread.
- Tennessee has a losing record of 1-4 versus Arizona in its previous five meetings.
- Tennessee has a losing record of 0-5 on the road in its last five games.
- The Tennessee Volunteers have a record of 0-6 against the spread in their previous six games against teams from the National Football Conference team.
- Over the course of its last nine games against teams from the National Football Conference West division, Tennessee has a head-to-head record of 3-6.
- Tennessee has a record of 1-5 against the spread in its previous six games played in the month of October.
- All five of Tennessee’s most recent seven games played in week 5 have resulted in the total going UNDER.
Tennessee Last 10 Games
| Date | Opponent | Score | Spread | Total | Moneyline |
|---|---|---|---|---|---|
|
9/28/25
|
@HOU
|
L 26-0
|
L+5.5
|
U44.5
|
L+180
|
|
9/21/25
|
IND
|
L 41-20
|
L-1.5
|
O45.5
|
L-122
|
|
9/14/25
|
LAR
|
L 33-19
|
L+4.5
|
O45.5
|
L+170
|
|
9/07/25
|
@DEN
|
L 20-12
|
L+7.0
|
U40.5
|
L+290
|
|
1/05/25
|
HOU
|
L 23-14
|
L+3.0
|
U45
|
L+130
|
|
12/29/24
|
@JAC
|
L 20-13
|
L+4.0
|
U46
|
L+160
|
|
12/22/24
|
@IND
|
L 38-30
|
L+3.5
|
O44.5
|
L+145
|
|
12/15/24
|
CIN
|
L 37-27
|
L+4.5
|
O46
|
L+170
|
|
12/08/24
|
JAC
|
L 10-6
|
L+2.0
|
U45
|
L+105
|
|
12/01/24
|
@WAS
|
L 42-19
|
L+1.5
|
O46.5
|
L+102
|
Titans vs Cardinals Betting Prediction: Tennessee Offense
Overall
| TEN Offense | Off. Rank | Stat | Def. Rank | ARI Defense |
|---|---|---|---|---|
| 17.00 | 28 | Points Scored | 5 | 17.00 |
| 133.67 | 32 | Passing Yards | 30 | 264.33 |
| 88.67 | 28 | Rushing Yards | 4 | 76.33 |
| 29:50 | 19 | Time on Field | 9 | 28:16 |
| 61.33 | 17 | Number of Plays | 30 | 69.33 |
| 3.63 | 32 | Yards Per Play | 12 | 4.91 |
Scoring
| TEN Offense | Off. Rank | Stat | Def. Rank | ARI Defense |
|---|---|---|---|---|
| 17.00 | 28 | Points Scored | 5 | 17.00 |
| 2.00 | 29 | First Quarter | 3 | 1.00 |
| 7.33 | 16 | Second Quarter | 9 | 5.33 |
| 4.33 | 18 | Third Quarter | 4 | 2.00 |
| 3.33 | 31 | Fourth Quarter | 22 | 8.67 |
Passing
| TEN Offense | Off. Rank | Stat | Def. Rank | ARI Defense |
|---|---|---|---|---|
| 133.67 | 32 | Passing Yards | 30 | 264.33 |
| 33.00 | 15 | Pass Attempts | 32 | 47.33 |
| 18.00 | 29 | Pass Completions | 32 | 29.67 |
| 5.00 | 32 | Sacks | 25 | 1.67 |
| 35.00 | 1 | Sack Yards | 9 | 11.00 |
| 7.43 | 32 | Yards Per Pass | 10 | 8.91 |
Rushing
| TEN Offense | Off. Rank | Stat | Def. Rank | ARI Defense |
|---|---|---|---|---|
| 88.67 | 28 | Rushing Yards | 4 | 76.33 |
| 23.33 | 26 | Rush Attempts | 4 | 20.33 |
| 3.80 | 23 | Yards Per Rush | 10 | 3.75 |
Turn Overs
| TEN Offense | Off. Rank | Stat | Def. Rank | ARI Defense |
|---|---|---|---|---|
| 0.33 | 15 | Interceptions | 11 | 0.67 |
| 1.00 | 23 | Fumbles | 24 | 0.33 |
| 1.00 | 31 | Fumbles Lost | 13 | 0.33 |
| 1.33 | 22 | Total Turnovers | 13 | 1.00 |
| 10.33 | 32 | Penalties | 9 | 8.33 |
| 87.00 | 31 | Penalty Yards | 3 | 80.33 |
Drives & Special Teams
| TEN Offense | Off. Rank | Stat | Def. Rank | ARI Defense |
|---|---|---|---|---|
| 29:50 | 19 | Time on Field | 9 | 28:16 |
| 61.33 | 17 | Number of Plays | 30 | 69.33 |
| 3.63 | 32 | Yards Per Play | 12 | 4.91 |
| 4.67 | 30 | Punts | 23 | 3.00 |
| 49.80 | 9 | Punt Average | 15 | 47.23 |
| 151.33 | 10 | Return Yards | 15 | 125.67 |
Titans vs Cardinals Betting Prediction: Arizona
The Cardinals, meanwhile, have been more competitive and balanced, despite their own inconsistencies. Arizona has covered the spread in ten of its last fifteen games, showing resilience even in losses. Their defense has been particularly impressive, ranking in the top five in scoring defense and proving difficult to break down in the red zone. Offensively, Arizona leans on a rushing attack that punishes defenses and keeps the chains moving. They also have a perfect ATS record against AFC teams in recent meetings, which is a major red flag for a struggling Titans squad.
Titans vs Cardinals Betting Prediction: Arizona Trends
- Over the past 15 games, Arizona has a record of 10-5 against the spread.
- In four of Arizona’s most recent six games, the total has been under the money.
- There have been four of Arizona’s last five games against Tennessee in which the total has been UNDER.
- There have been four of Arizona’s last five home games in which the total has been above.
- After seven games versus teams from the American Football Conference, Arizona has a perfect record against the spread (ATS) in all seven of those games.
- A total of five of Arizona’s most recent five games against opponents from the American Football Conference South division have ended with the total falling below the point spread.
- In its previous five games played in the month of October, Arizona has a record of 4-1 against the spread.
- The Arizona Wildcats have a winning record of 5-2 in their past seven games played in week 5.
- In the last six games that have been played on a Sunday, Arizona has a winning record of 4-2 against the spread.
Arizona Last 10 Games
| Date | Opponent | Score | Spread | Total | Moneyline |
|---|---|---|---|---|---|
|
9/25/25
|
SEA
|
L 23-20
|
L-2.5
|
U46.5
|
L-130
|
|
9/21/25
|
@SF
|
L 16-15
|
W+3.5
|
U47.5
|
L+150
|
|
9/14/25
|
CAR
|
W 27-22
|
W-4.5
|
O46.5
|
W-198
|
|
9/07/25
|
@NO
|
W 20-13
|
W-4.5
|
U41.5
|
W-200
|
|
1/05/25
|
SF
|
W 47-24
|
W+5.5
|
O43
|
W+190
|
|
12/28/24
|
@LAR
|
L 13-9
|
W+5.5
|
U48.5
|
L+195
|
|
12/22/24
|
@CAR
|
L 36-30
|
L-1.0
|
O45.5
|
L-118
|
|
12/15/24
|
NE
|
W 30-17
|
W-3.0
|
O44
|
W-155
|
|
12/08/24
|
SEA
|
L 30-18
|
L-1.0
|
O47.5
|
L-112
|
|
12/01/24
|
@MIN
|
L 23-22
|
W+1.5
|
U45.5
|
LEVEN
|
Titans vs Cardinals Betting Prediction: Arizona Offense
Overall
| TEN Defense | Def. Rank | Stat | Off. Rank | ARI Offense |
|---|---|---|---|---|
| 31.33 | 30 | Points Scored | 19 | 20.67 |
| 228.00 | 22 | Passing Yards | 28 | 165.00 |
| 145.67 | 29 | Rushing Yards | 16 | 111.33 |
| 30:10 | 17 | Time on Field | 10 | 31:43 |
| 61.00 | 18 | Number of Plays | 22 | 57.67 |
| 6.13 | 30 | Yards Per Play | 24 | 4.79 |
Scoring
| TEN Defense | Def. Rank | Stat | Off. Rank | ARI Offense |
|---|---|---|---|---|
| 31.33 | 30 | Points Scored | 19 | 20.67 |
| 9.00 | 31 | First Quarter | 16 | 4.33 |
| 4.33 | 5 | Second Quarter | 7 | 9.00 |
| 9.00 | 32 | Third Quarter | 13 | 4.33 |
| 9.00 | 24 | Fourth Quarter | 32 | 3.00 |
Passing
| TEN Defense | Def. Rank | Stat | Off. Rank | ARI Offense |
|---|---|---|---|---|
| 228.00 | 22 | Passing Yards | 28 | 165.00 |
| 32.67 | 19 | Pass Attempts | 23 | 29.67 |
| 22.00 | 23 | Pass Completions | 22 | 20.00 |
| 0.67 | 31 | Sacks | 17 | 2.33 |
| 6.00 | 4 | Sack Yards | 13 | 15.67 |
| 10.36 | 23 | Yards Per Pass | 27 | 8.25 |
Rushing
| TEN Defense | Def. Rank | Stat | Off. Rank | ARI Offense |
|---|---|---|---|---|
| 145.67 | 29 | Rushing Yards | 16 | 111.33 |
| 27.67 | 21 | Rush Attempts | 17 | 25.67 |
| 5.27 | 29 | Yards Per Rush | 17 | 4.34 |
Turn Overs
| TEN Defense | Def. Rank | Stat | Off. Rank | ARI Offense |
|---|---|---|---|---|
| 1.00 | 10 | Interceptions | 7 | 0.33 |
| 1.00 | 16 | Fumbles | 2 | 0.33 |
| 0.67 | 12 | Fumbles Lost | 1 | 0.00 |
| 1.67 | 9 | Total Turnovers | 4 | 0.33 |
| 4.67 | 32 | Penalties | 23 | 8.67 |
| 32.33 | 32 | Penalty Yards | 16 | 60.00 |
Drives & Special Teams
| TEN Defense | Def. Rank | Stat | Off. Rank | ARI Offense |
|---|---|---|---|---|
| 30:10 | 17 | Time on Field | 10 | 31:43 |
| 61.00 | 18 | Number of Plays | 22 | 57.67 |
| 6.13 | 30 | Yards Per Play | 24 | 4.79 |
| 2.33 | 29 | Punts | 14 | 3.67 |
| 47.84 | 17 | Punt Average | 4 | 51.73 |
| 119.67 | 12 | Return Yards | 18 | 121.33 |
Our Pick: Arizona Cardinals 🏈
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Titans vs Cardinals Betting Prediction and Pick Week 5, 2025, by YouWager.lv.