Ohio State vs Indiana Prediction and Pick, Week 15, College Football Picks

Ohio State vs Indiana Prediction and Pick, Week 15, College Football Picks. Place a bet on this game at YouWager.lv..

Ohio State vs Indiana Prediction – Week 15, College Football Picks

Now we have the Ohio State vs Indiana Prediction for both teams.

A Big Ten championship game between the Indiana Hoosiers and the Ohio State Buckeyes is scheduled to take place at Lucas Oil Stadium on Saturday evening at 8:00 PM. With twelve victories so far this season, Indiana is now ranked as the second best team in the country. They are entering the Big 10 championship game on the heels of a 53-point victory over Purdue on the road. After claiming an 18-point victory over Michigan on the road to close off the regular season, the Ohio State Buckeyes have risen to the top spot in the national rankings and are currently unbeaten in this college football season.

This year, Fernando Mendoza has led the Indiana offensive in terms of total offense with 2758 yards, 32 touchdowns, and 211 completions. In addition, he has carried the ball 64 times and accumulated 243 yards and six touchdowns. A total of 163 carries have resulted in Roman Hemby accumulating 866 yards and six touchdowns, making him the leading rusher for Indiana. Over the course of 58 receptions, Omar Cooper Jr. has accumulated 840 yards and 11 touchdowns, making him the team’s leading receiver. Over the course of this season, Elijah Sarratt has accumulated 650 yards and 11 touchdowns on 48 receptions.

This season, the Ohio State offense is led by Julian Sayin, who has thrown for 3065 yards and 30 touchdowns while completing 258 passes from the field. Bo Jackson is the team’s leading ball carrier, having carried the ball 151 times for a total of 952 yards and scoring five touchdowns. With 89 carries, CJ Donaldson has contributed 330 yards and 10 touchdowns to the team’s total. A total of 72 receptions for 942 yards and 11 touchdowns have been made by Jeremiah Smith, making him the most valuable target for the Ohio State offense. The current season has seen Carnell Tate add 44 receptions, 793 yards, and eight touchdowns to his total.

This is a game between the two best teams in the country, and on Saturday that matchup will live up to the hype that has been surrounding it. Saturday will be a full-fledged competition between two clubs that have yet to suffer a loss in their respective seasons. It is anticipated that Indiana will maintain a close enough distance during the Big 10 championship to cover the number, but it is Ohio State that will emerge victorious once the dust settles over Illinois.

✅ Our Ohio State vs Indiana Pick: OHIO STATE

Ohio State vs Indiana Prediction: Trends

Since Indiana’s last six games, the total has been over in five of those games.
In its last ten games, Indiana has a perfect record against the spread.
After six games versus Ohio State, Indiana has a record of 2-4 against the spread.
In its last ten meetings versus Ohio State, Indiana has a point differential of 0-10.
The Indiana Hoosiers have a perfect record of 5-0 in their previous five games versus teams from the Big Ten conference.
Six out of Indiana’s last seven games against opponents from the East Division division have resulted in the total going over the point spread.
After playing five games in December, Indiana has a record of 1-4 on the road.
In four of Indiana’s most recent five games that have been played on a Saturday, the total has been above.
With a record of 5-2 against the spread in its last seven games, Indiana has been the underdog.
Over the past nine games, Ohio State has a record of 8-1 against the spread.
In five of Ohio State’s most recent seven games, the total has been underwritten.
Ohio State has a perfect record of 10-0 in its previous ten games.
During Ohio State’s last eight games versus Indiana, the total has been above in seven of those games.
The Ohio State Buckeyes have a perfect record of 5-0 in their previous five games versus teams from the Big Ten conference.
Over the course of its previous seven games versus opponents from the East Division, Ohio State has a record of 6-1 against the spread.
At the end of the month of December, Ohio State has a record of 7-3 against the spread.
On Saturdays, Ohio State has a record of 11-1-1 against the spread in its previous 13 games played.
When Ohio State has been the favorite in a game, the total has been UNDER in eight of the last twelve games that they have played.
All four of Ohio State’s most recent six games that have been played at home on a Saturday have resulted in the total going over.

Ohio State vs Indiana Prediction: Head to Head

Date	Team	Opp	Close	Result	ATS/OU
Nov 23, 2024	Indiana	@Ohio State	+10.5 / 52.5	Lost 15-38	Lost / Over
Sep 2, 2023	Indiana	Ohio State	+30.5 / 59.5	Lost 3-23	Won / Under
Nov 12, 2022	Indiana	@Ohio State	+40.5 / 62	Lost 14-56	Lost / Over
Oct 23, 2021	Indiana	Ohio State	+21 / 58.5	Lost 7-54	Lost / Over
Nov 21, 2020	Indiana	@Ohio State	+21 / 66.5	Lost 35-42	Won / Over
Sep 14, 2019	Indiana	Ohio State	+17 / 60.5	Lost 10-51	Lost / Over
Oct 6, 2018	Indiana	@Ohio State	+27.5 / 63	Lost 26-49	Won / Over
Aug 31, 2017	Indiana	Ohio State	+20 / 55.5	Lost 21-49	Lost / Over
Oct 8, 2016	Indiana	Ohio State	-28 / 60.5	Lost 0-0	Lost / Under
Oct 3, 2015	Indiana	@Ohio State	-21.5 / 64.5	Lost 0-0	Lost / Under

Ohio State vs Indiana Prediction: Hoosiers Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
11/28/25	@PUR	W 56-3	W-26.5	O50.5	W-4500
11/15/25	WIS	W 31-7	L-31.0	U43.5	W-20000
11/08/25	@PSU	W 27-24	W+16.5	U53.5	W+530
11/01/25	@MAR	W 55-10	W-16.5	O51.5	W-2800
10/25/25	UCLA	W 56-6	W-21.5	O54.5	W-2300
10/18/25	MSU	W 38-13	W-24.5	O50.5	W-4000
10/11/25	@ORE	W 30-20	W+14.0	U55.5	W+480
9/27/25	@IOW	W 20-15	W-2.5	U48.5	W-125
9/20/25	ILL	W 63-10	W-3.0	O54.5	W-192
9/12/25	INDS	W 73-0	W-41.5	O57.5	W-3500

Ohio State vs Indiana Prediction: Buckeyes Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
11/29/25	@MICH	W 27-9	W-5.5	U47.5	W-184
11/22/25	RUT	W 42-9	W-32.5	U55.5	W-10000
11/15/25	UCLA	W 48-10	W-31.5	O48.5	W-10000
11/08/25	@PUR	W 34-10	L-27.5	U49.5	W-7000
11/01/25	PSU	W 38-14	W-4.5	O50.5	W-160
10/18/25	@WIS	W 34-0	W-26.5	U41.5	W-10000
10/11/25	@ILL	W 34-16	W-13.5	U50.5	W-580
10/04/25	MIN	W 42-3	W-21.0	U46.5	W-3000
9/27/25	@WAS	W 24-6	W-14.0	U48.5	W-580
9/13/25	OHI	W 37-9	L-32.0	U54.5	W-10000

Ohio State vs Indiana Prediction: Hoosiers Offense

Overall

INDY Offense	Off. Rank	Stat	Def. Rank	OSU Defense
44.33	2	Points Scored	1	7.75
254.08	42	Passing Yards	1	121.33
229.75	9	Rushing Yards	4	81.67
33:39	7	Time on Field	5	26:12
67.50	61	Number of Plays	1	53.92
7.17	6	Yards Per Play	1	3.77

Scoring

INDY Offense	Off. Rank	Stat	Def. Rank	OSU Defense
44.33	2	Points Scored	1	7.75
10.17	6	First Quarter	1	1.00
12.50	8	Second Quarter	2	2.42
13.33	1	Third Quarter	5	1.92
8.33	31	Fourth Quarter	1	2.42

Passing

INDY Offense	Off. Rank	Stat	Def. Rank	OSU Defense
254.08	42	Passing Yards	1	121.33
26.67	109	Pass Attempts	3	24.42
19.17	69	Pass Completions	4	14.50
1.25	22	Sacks	28	2.50
7.75	113	Sack Yards	110	17.83
13.26	22	Yards Per Pass	1	8.37

Rushing

INDY Offense	Off. Rank	Stat	Def. Rank	OSU Defense
229.75	9	Rushing Yards	4	81.67
40.83	26	Rush Attempts	5	29.50
5.63	11	Yards Per Rush	5	2.77

Turn Overs

INDY Offense	Off. Rank	Stat	Def. Rank	OSU Defense
0.50	21	Interceptions	99	0.58
0.50	3	Fumbles	128	0.58
0.08	2	Fumbles Lost	92	0.42
0.58	3	Total Turnovers	106	1.00
3.67	6	Penalties	135	3.75
26.75	3	Penalty Yards	136	28.58

Drives & Special Teams

INDY Offense	Off. Rank	Stat	Def. Rank	OSU Defense
33:39	7	Time on Field	5	26:12
67.50	61	Number of Plays	1	53.92
7.17	6	Yards Per Play	1	3.77
2.50	12	Punts	15	5.25
41.89	90	Punt Average	129	45.18
54.33	75	Return Yards	3	22.83

Ohio State vs Indiana Prediction: Buckeyes Offense