Jaguars vs Cardinals Prediction and Pick, Week 12

Jaguars vs Cardinals Prediction and Pick, Week 12, NFL Betting Predictions. Place a bet on this game with the best odds.

Jaguars vs Cardinals Prediction – NFL Betting Predictions

Now we have the Jaguars vs Cardinals Prediction for both teams.

In light of the fact that Liam Coen has emphasized the importance of increasing the involvement of the run game, the Jacksonville Jaguars were able to get things moving on the ground against the Chargers. As the Jags rushed for 192 yards on 47 carries, Travis Etienne Jr. and Bhayshul Tuten both rushed for more than 70 yards and hit paydirt. Furthermore, the Jags won by a significant margin.

As of late, the Arizona Cardinals are having a difficult time putting an end to the run. This past weekend, Christian McCaffrey went for 81 yards on the ground, averaging more than six yards per carry. Zach Charbonnet and Kenneth Walker III both had successful games for the Seahawks last week, which resulted in the Seahawks gaining 198 yards on 46 attempts.

In Week 11, the Jaguars are anticipating the return of Brian Thomas Jr. from his injury, while Jakobi Meyers has shown to be a crucial weapon for Trevor Lawrence. Although Jacksonville is aware that it must continue to win games in order to qualify for the playoffs, the offense showed a significant improvement in their performance against the Chargers.

When the Cardinals’ inability to properly care for the football is taken into consideration, it is reasonable to expect that the Jaguars will cover the number in this game. The Jacksonville Jaguars are one of the finest teams in the National Football League (NFL) this season when it comes to making the most of mistakes, and Jacoby Brissett and his teammates have given up the ball five times over the course of the last two games.

For the first three games of this season, Jacksonville has only been favored three times, and the Jaguars have covered the spread twice with a push. It would be great if that pattern continued here.

I am currently at 47.5 points, which indicates that I am leaning over in this particular game. In Arizona’s previous six games, the Over has a record of 5-1, and in Jacksonville’s away games this season, the Over has a record of 4-0.

Lawrence will have more opportunities to be successful in the play-action game as a result of the Jaguars’ dedication to the run, which will help keep the Jaguars moving down the field. In addition, they will be successful against a Cardinal defense that is rated 28th in red-zone scoring ratings.

Jacksonville’s pass rush was a significant factor in the team’s success in limiting Los Angeles to just six scores. When playing against one of the poorest pass-protection groups in the NFL, the Jaguars were able to achieve a pressure rate of fifty percent.

Although they are ranked 23rd in terms of the number of sacks they allow, the Cardinals continue to have strong passing numbers. This season, Jacksonville’s pass defense has been one of the worst in the league, ranking 26th in terms of the number of passing yards allowed.

While Arizona’s offense is ranked 11th in terms of completion rate, it is ranked fifth in terms of converting on third down. In addition, Jacksonville is among the weakest teams in the league when it comes to stopping points from being scored inside the red zone, and the Cardinals should make the most of their quality drives.

✅ Our Jaguars vs Cardinals Pick: ARIZONA CARDINALS

Jaguars vs Cardinals Odds

Now, we have the Jaguars vs Cardinals odds:

TEAM	SPREAD	MONEYLINE	TOTAL
Jacksonville	-2.5	-145	47.5 O
Arizona	+2.5	+125	47.5 U

Jaguars vs Cardinals Prediction: Trends

Over the past five games, Jacksonville has a record of 1-4 against the spread.
In its last five games versus Arizona, Jacksonville has a record of 1-4 all-time.
In its last five games versus Arizona, Jacksonville has a record of 1-4 on the road.
There have been five of Jacksonville’s most recent five games that have ended with the total going over.
The Jacksonville Jaguars have a winning percentage of 2-7 in their previous nine games against teams that are members of the National Football Conference.
Over the course of its last 20 games versus teams from the National Football Conference West division, Jacksonville has a record of 2-18 against the spread.
Out of the six games that Jacksonville has played in November, the total has been over in four of those games.
During the 12th week of the season, Jacksonville has a record of 2-8 against the spread.
In five of Arizona’s most recent six games, the total has been taken over.
In its last eight games, Arizona has a record of 1-7 against the spread.
In four of Arizona’s last six games versus Jacksonville, the total has been higher than the point spread.
Seven of Arizona’s previous eight games played at home have resulted in the total going over.
Over the course of its most recent nine games versus teams from the American Football Conference, Arizona has a record of 8-1 against the spread.
In its last five games against teams from the American Football Conference South division, Arizona has a record of 1-4 in terms of its overall performance.
Out of the six games that Arizona has played in November, the total has been UNDER in four of those games.
As of the end of week 12, Arizona has a losing record of 0-5 against the spread.
When playing as the underdog, Arizona has a record of 9-3 against the spread in its last 12 games.

Jaguars vs Cardinals Prediction: Head to Head

Date	Opponent	Score	Spread	Total	Moneyline
9/26/21	@JAC	ARI 31-19	JAC+8.0	U51.5	JAC+300
11/26/17	@ARI	ARI 27-24	NL	NL	NL
11/17/13	@JAC	ARI 27-14	NL	NL	NL
9/20/09	@JAC	ARI 31-17	NL	NL	NL
11/27/05	@ARI	JAC 24-17	NL	NL	NL

Jaguars vs Cardinals Prediction: Jacksonville Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
11/16/25	LAC	W 35-6	W+1.5	U46.5	WEVEN
11/09/25	@HOU	L 36-29	L+3.5	O45.5	L+145
11/02/25	@LV	W 30-29	W+1.5	O45.5	WEVEN
10/19/25	LAR	L 35-7	L+4.5	U47.5	L+176
10/12/25	SEA	L 20-12	L-1.5	U46.5	L-122
10/06/25	KC	W 31-28	W+4.5	O47.5	W+180
9/28/25	@SF	W 26-21	W+3.5	U48.5	W+119
9/21/25	HOU	W 17-10	W-1.5	U46.5	W-127
9/14/25	@CIN	L 31-27	W+5.5	O49.5	L+198
9/07/25	CAR	W 26-10	W-2.5	U46.5	W-161

Jaguars vs Cardinals Prediction: Arizona Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
11/16/25	SF	L 41-22	L+1.5	O47.5	LEVEN
11/09/25	@SEA	L 44-22	L+1.5	O44.5	LEVEN
11/03/25	@DAL	W 27-17	W+1.5	U52.5	W+102
10/19/25	GB	L 27-23	L+1.5	O47.5	LEVEN
10/12/25	@IND	L 31-27	L-1.5	O47.5	L-122
10/05/25	TEN	L 22-21	L-5.5	U46.5	L-225
9/25/25	SEA	L 23-20	L-2.5	U46.5	L-130
9/21/25	@SF	L 16-15	W+3.5	U47.5	L+150
9/14/25	CAR	W 27-22	W-4.5	O46.5	W-198
9/07/25	@NO	W 20-13	W-4.5	U41.5	W-200

Jaguars vs Cardinals Prediction: Jacksonville Offense

Overall

JAC Offense	Off. Rank	Stat	Def. Rank	ARI Defense
24.00	14	Points Scored	25	25.60
199.40	21	Passing Yards	20	221.40
127.50	8	Rushing Yards	16	112.20
32:44	1	Time on Field	7	28:26
65.90	1	Number of Plays	20	62.40
4.96	27	Yards Per Play	16	5.35

Scoring

JAC Offense	Off. Rank	Stat	Def. Rank	ARI Defense
24.00	14	Points Scored	25	25.60
4.00	19	First Quarter	23	5.40
7.10	15	Second Quarter	21	7.50
5.20	13	Third Quarter	2	3.20
7.00	16	Fourth Quarter	28	9.50

Passing

JAC Offense	Off. Rank	Stat	Def. Rank	ARI Defense
199.40	21	Passing Yards	20	221.40
33.80	13	Pass Attempts	23	34.30
20.20	21	Pass Completions	20	22.20
2.60	21	Sacks	25	1.90
15.70	11	Sack Yards	14	13.80
9.87	21	Yards Per Pass	15	9.97

Rushing

JAC Offense	Off. Rank	Stat	Def. Rank	ARI Defense
127.50	8	Rushing Yards	16	112.20
29.50	4	Rush Attempts	17	26.20
4.32	17	Yards Per Rush	18	4.28

Turn Overs

JAC Offense	Off. Rank	Stat	Def. Rank	ARI Defense
0.80	23	Interceptions	17	0.60
0.80	6	Fumbles	2	1.40
0.20	4	Fumbles Lost	4	0.70
1.00	10	Total Turnovers	9	1.30
8.40	31	Penalties	22	6.20
70.30	31	Penalty Yards	12	57.40

Drives & Special Teams

JAC Offense	Off. Rank	Stat	Def. Rank	ARI Defense
32:44	1	Time on Field	7	28:26
65.90	1	Number of Plays	20	62.40
4.96	27	Yards Per Play	16	5.35
3.50	17	Punts	32	2.70
47.16	18	Punt Average	32	50.44
142.30	8	Return Yards	20	139.90

Jaguars vs Cardinals Prediction: Arizona Offense