NFL Week 4 Schedule 2026: Every Game, Best Matchups, Betting Guide, Fun Facts & AI Predictions
Week 4 is when the NFL season starts getting serious.
Some teams are fighting to stay undefeated.
Others are trying to avoid a disastrous 1 and 3 start.
The playoff picture is still months away, but history shows teams that start 3 and 1 or better dramatically improve their postseason chances. Week 4 also features the first NFL game in London, several outstanding division rivalries and another exciting Sunday Night Football matchup.
If you’re betting Week 4, YouWager.lv is the perfect place to compare point spreads, moneylines, totals, player props, Same Game Parlays and live betting throughout the weekend.
Week 4 Quick Answer
Week 4 Dates
October 1 through October 5, 2026
Games
16
Thursday Night Football
Steelers at Browns
Sunday Night Football
Lions at Panthers
Monday Night Football
Falcons at Saints
International Game
Colts vs Commanders (London)
Division Games
Steelers vs Browns
Chiefs vs Raiders
Falcons vs Saints
Jets vs Bears
Complete NFL Week 4 Schedule
Thursday Night Football
Steelers at Browns
NFL London Game
Colts vs Commanders
Sunday Early Games
Titans at Ravens
Patriots at Bills
Jets at Bears
Jaguars at Bengals
Cowboys at Texans
Cardinals at Giants
Rams at Eagles
Packers at Buccaneers
Sunday Afternoon
Dolphins at Vikings
Chiefs at Raiders
Chargers at Seahawks
Broncos at 49ers
Sunday Night Football
Lions at Panthers
Monday Night Football
Falcons at Saints
You can always find updated kickoff times, betting lines and player props throughout the week at YouWager.lv while checking the official NFL schedule for any changes.
What is the biggest game of Week 4?
Kansas City Chiefs vs Las Vegas Raiders
Patrick Mahomes.
Pete Carroll.
An AFC West rivalry.
Arrowhead has become one of the NFL’s toughest places to play, but Las Vegas has built a roster capable of challenging Kansas City.
This should become one of the highest bet games of the weekend on YouWager.lv.
What is the best betting game of Week 4?
Rams vs Eagles
Two NFC contenders.
Playoff atmosphere.
Elite quarterbacks.
Balanced rosters.
This is exactly the type of matchup where sportsbooks usually post tight spreads, creating tremendous betting value.
Watch line movement throughout the week on YouWager.lv because this game could move several points before kickoff.
Which game has the best quarterback matchup?
Patrick Mahomes vs Geno Smith
Mahomes remains the NFL’s gold standard.
Geno Smith continues proving he belongs among the league’s most reliable veterans.
Whenever Mahomes plays a division rival, every possession becomes important.
Which game is best for fantasy football?
Jaguars vs Bengals
Joe Burrow.
Ja’Marr Chase.
Brian Thomas Jr.
Trevor Lawrence.
Travis Hunter.
Tee Higgins.
Expect fantasy football managers to have several starters in this game.
Which rookie should fans watch?
Travis Hunter
By Week 4, Jacksonville’s rookie could already be one of the NFL’s biggest stories.
Whether he contributes on offense, defense or both, every snap will receive national attention.
Other rookies worth watching include:
Ashton Jeanty
Omarion Hampton
Matthew Golden
RJ Harvey
Jihaad Campbell
Which game could produce the biggest upset?
Seattle Seahawks over the Chargers
The Chargers may enter as favorites, but Seattle remains one of the NFL’s loudest home-field environments.
Travel, crowd noise and an improving Seahawks roster make this one of Week 4’s best upset candidates.
If you’re looking for value on the underdog, this could become one of the week’s most popular picks at YouWager.lv.
Which rivalry game should fans not miss?
Steelers vs Browns
No rivalry in the AFC North is ever easy.
Physical football.
Elite defenses.
Hard hits.
Every yard matters.
These games almost always stay close regardless of records.
Which defense has the toughest assignment?
Las Vegas Raiders
Stopping Patrick Mahomes has frustrated NFL defenses for nearly a decade.
Kansas City continues surrounding Mahomes with speed and explosive playmakers.
Containing that offense for four quarters is one of football’s hardest challenges.
Which offense has the toughest assignment?
Dallas Cowboys
Houston’s defense continues improving every season.
Playing on the road against C.J. Stroud and one of the AFC’s fastest-rising teams will not be easy.
Which game is best for live betting?
Chiefs vs Raiders
Division games often swing dramatically during the second half.
Mahomes has built a career on fourth-quarter comebacks.
Pete Carroll has always been one of the league’s best in-game coaches.
Expect live betting to stay active all afternoon at YouWager.lv.
Which team faces the most pressure?
Philadelphia Eagles
The Eagles entered the season with Super Bowl expectations.
A slow start would immediately increase pressure inside one of the NFL’s toughest divisions.
Hosting the Rams makes this a statement game.
Which team could surprise everyone?
Chicago Bears
If Caleb Williams begins the season well, Week 4 against the Jets could become another opportunity to prove Chicago belongs among the NFC playoff contenders.
Which Week 4 game is best for Same Game Parlays?
Chiefs vs Raiders
Patrick Mahomes passing touchdowns.
Brock Bowers receiving yards.
Ashton Jeanty rushing yards.
Xavier Worthy receiving yards.
Game total.
Chiefs to win.
This is exactly the type of game where YouWager.lv offers one of the largest Same Game Parlay selections of the week.
Which Week 4 game has the best Over potential?
Jaguars vs Bengals
Joe Burrow loves pushing the ball downfield.
Trevor Lawrence continues leading one of the AFC’s most explosive young offenses.
If both quarterbacks play well, this game could easily become one of Week 4’s highest-scoring contests.
Which game should bettors watch for line movement?
Rams vs Eagles
Sharp bettors usually attack games featuring evenly matched playoff contenders.
Don’t be surprised if this spread changes several times before kickoff.
Track every movement throughout the week at YouWager.lv.
One fun fact
Week 4 features the NFL’s first London game of the season, with the Colts and Commanders meeting at Tottenham Hotspur Stadium as the league continues expanding internationally.
Another fun fact
By the end of Week 4, every NFL team has completed almost one quarter of the regular season, making this one of the first weeks where playoff projections begin carrying real significance.
AI Power Rankings for Week 4 Matchups
Best Overall Game
Chiefs vs Raiders
Best Offensive Game
Jaguars vs Bengals
Best Defensive Game
Steelers vs Browns
Best Division Rivalry
Chiefs vs Raiders
Best Quarterback Battle
Patrick Mahomes vs Geno Smith
Best Rookie Showcase
Jaguars vs Bengals
Best Fantasy Matchup
Jaguars vs Bengals
Best Live Betting Opportunity
Chiefs vs Raiders
Best Same Game Parlay
Chiefs vs Raiders
Best International Game
Colts vs Commanders
Biggest Upset Alert
Seahawks over Chargers
Lock of the Week
Bills over Patriots
For bettors looking to build parlays, attack player props or find live betting value, Week 4 offers one of the strongest slates of the young season, and YouWager.lv provides markets for every game from Thursday Night Football through Monday Night Football.
Frequently Asked Questions
When does NFL Week 4 start?
Week 4 begins on Thursday, October 1, 2026, with the Steelers visiting the Browns on Thursday Night Football.
What is the international game in Week 4?
The Indianapolis Colts and Washington Commanders meet in London at Tottenham Hotspur Stadium.
What is the Sunday Night Football game?
The Detroit Lions visit the Carolina Panthers on NBC.
What is the Monday Night Football game?
The Atlanta Falcons visit the New Orleans Saints on ESPN.
Which Week 4 game is best for fantasy football?
Jaguars vs Bengals projects as one of the strongest fantasy football matchups because of the elite quarterbacks and explosive receivers on both teams.
Which Week 4 game is best for betting?
Chiefs vs Raiders should attract the highest betting volume thanks to the AFC West rivalry, Patrick Mahomes and what is expected to be one of the week’s biggest betting handles.
Where can I bet on every Week 4 NFL game?
You can bet every Week 4 matchup with YouWager.lv, including point spreads, moneylines, totals, player props, Same Game Parlays, teaser bets and live in-game wagering.
2026/27 NFL Playoffs Betting Guides
NFL Wild Card Weekend 2026 Betting Guide
NFL Divisional Round 2027 Betting Guide
NFL Conference Championship Games 2027 Betting Guide
Super Bowl LXI 2027 Betting Guide
Full NFL Regular Season Schedule 2026/27
NFL Week 1 Schedule 2026
NFL Week 2 Schedule 2026
NFL Week 3 Schedule 2026
NFL Week 4 Schedule 2026
NFL Week 5 Schedule 2026
NFL Week 6 Schedule 2026
NFL Week 7 Schedule 2026
NFL Week 8 Schedule 2026
NFL Week 9 Schedule 2026
NFL Week 10 Schedule 2026
NFL Week 11 Schedule 2026
NFL Week 12 Schedule 2026
NFL Week 13 Schedule 2026
NFL Week 14 Schedule 2026
NFL Week 15 Schedule 2026
NFL Week 16 Schedule 2026
NFL Week 17 Schedule 2026
NFL Week 18 Schedule 2026
