NFL Week 12 Schedule 2026: Thanksgiving Games, Best Matchups, Betting Guide, Fun Facts & AI Predictions

Week 12 is one of the biggest weeks of the NFL season because Thanksgiving football is back. Millions of fans gather to watch football throughout the holiday, making this one of the most-watched weekends of the entire year. Along with three Thanksgiving Day games, Week 12 also features a Black Friday showdown, a massive AFC Championship rematch on Sunday Night Football and another prime-time game to close the week.

Whether you’re looking for point spreads, moneylines, player props, Same Game Parlays or live betting, YouWager.lv is the perfect place to bet every Thanksgiving and Week 12 NFL game.

Week 12 Quick Answer

Week 12 Dates

November 25 through November 30, 2026

Games

16

Teams on Bye

None

Wednesday Night Football

Packers at Rams

Thanksgiving Day Games

Bears at Lions

Eagles at Cowboys

Chiefs at Bills

Black Friday Football

Broncos at Steelers

Sunday Night Football

Patriots at Chargers

Monday Night Football

Panthers at Buccaneers

Complete NFL Week 12 Schedule

Wednesday Night

Packers at Rams

Thanksgiving Afternoon

Bears at Lions

Thanksgiving Late Afternoon

Eagles at Cowboys

Thanksgiving Night

Chiefs at Bills

Black Friday

Broncos at Steelers

Sunday Early Games

Saints at Bengals

Raiders at Browns

Ravens at Texans

Giants at Colts

Jets at Dolphins

Falcons at Vikings

Sunday Afternoon

Titans at Jaguars

Commanders at Cardinals

Seahawks at 49ers

Sunday Night Football

Patriots at Chargers

Monday Night Football

Panthers at Buccaneers

The official Week 12 schedule is available on NFL.com.

What is the biggest game of Week 12?

Kansas City Chiefs vs Buffalo Bills

It doesn’t get much bigger.

Patrick Mahomes.

Josh Allen.

Thanksgiving Night.

Two AFC powerhouses.

A possible AFC Championship preview.

Every meeting between these teams feels like playoff football, and playing on Thanksgiving only makes the matchup even bigger.

Expect this to become one of the highest-bet games of the entire regular season at YouWager.lv.

What is the best betting game of Week 12?

Chiefs vs Bills

These teams are almost always separated by just a few points.

That creates tremendous betting value.

Spread bettors.

Live bettors.

Player prop bettors.

Same Game Parlay players.

Everyone will be watching this matchup.

Watch line movement throughout Thanksgiving week at YouWager.lv because this number could move several times before kickoff.

Which Thanksgiving game should fans watch?

Every one.

Bears vs Lions continues one of the NFL’s oldest Thanksgiving traditions.

Eagles vs Cowboys brings together two NFC East rivals with enormous playoff implications.

Chiefs vs Bills may be the best Thanksgiving Night game the NFL has scheduled in years.

Which game has the best quarterback matchup?

Patrick Mahomes vs Josh Allen

Many consider this the best quarterback rivalry in today’s NFL.

Two MVPs.

Two Super Bowl contenders.

Two quarterbacks capable of changing a game in one play.

Which game is best for fantasy football?

Chiefs vs Bills

Patrick Mahomes.

Josh Allen.

James Cook.

Travis Kelce.

Xavier Worthy.

Dalton Kincaid.

Fantasy managers should have several starters playing under the Thanksgiving lights.

Which rookie should fans watch?

Ashton Jeanty

Week 12 gives the Raiders rookie another opportunity to strengthen his Offensive Rookie of the Year campaign against Cleveland.

Other rookies worth following include

Travis Hunter

Matthew Golden

RJ Harvey

Omarion Hampton

Jihaad Campbell

By Thanksgiving, the Rookie of the Year races usually become much clearer.

Which game could produce the biggest upset?

Denver Broncos over Pittsburgh Steelers

Black Friday football is new territory for the NFL.

Road underdogs often thrive when expectations are low.

Bo Nix and Denver could become one of the biggest surprises of Thanksgiving weekend.

Look for attractive underdog prices and alternate spreads at YouWager.lv.

Which rivalry game should fans not miss?

Eagles vs Cowboys

No introduction needed.

Dak Prescott.

Jalen Hurts.

Thanksgiving.

National television.

First place in the NFC East could be on the line.

Which defense has the toughest assignment?

Buffalo Bills

Stopping Patrick Mahomes on Thanksgiving Night is one of the toughest jobs in football.

Kansas City’s offense traditionally improves during the second half of the season.

Which offense has the toughest assignment?

Chicago Bears

Detroit remains one of the NFC’s most complete teams.

Opening Thanksgiving against the Lions in Detroit is one of the NFL’s toughest annual traditions.

Which game is best for live betting?

Chiefs vs Bills

Mahomes has built a career on fourth-quarter comebacks.

Josh Allen never stops attacking.

Momentum can swing in seconds.

This should become one of the busiest live betting games of the entire season at YouWager.lv.

Which team faces the most pressure?

Dallas Cowboys

Every Thanksgiving game carries extra attention.

Hosting Philadelphia with playoff implications makes this one of Dallas’ biggest regular-season games.

A victory could reshape the NFC East race.

Which team could surprise everyone?

Arizona Cardinals

Hosting Washington late in the season gives Arizona an opportunity to stay alive in the NFC playoff race.

A win here could completely change the outlook of its season.

Which Week 12 game is best for Same Game Parlays?

Chiefs vs Bills

Patrick Mahomes passing touchdowns.

Josh Allen passing yards.

James Cook rushing yards.

Travis Kelce receiving yards.

Xavier Worthy receiving yards.

Game total.

Chiefs to win.

Thanksgiving games traditionally receive expanded Same Game Parlay menus at YouWager.lv, making this one of the biggest betting events of the year.

Which Week 12 game has the best Over potential?

Chiefs vs Bills

Elite quarterbacks.

Elite coaches.

Explosive offenses.

Few games have more potential to become a shootout than this AFC rivalry.

Which game should bettors watch for line movement?

Eagles vs Cowboys

Public bettors almost always back Dallas on Thanksgiving.

Sharp bettors often wait for the best number.

That combination frequently creates significant betting movement before kickoff.

Track every odds update throughout Thanksgiving week at YouWager.lv.

One fun fact

Week 12 features three Thanksgiving Day games, continuing one of the NFL’s greatest traditions that dates back decades and consistently delivers some of the league’s highest television ratings.

Another fun fact

The Chiefs vs Bills Thanksgiving Night game has all the ingredients of a future AFC Championship Game, making it one of the most anticipated holiday matchups in recent NFL history.

AI Power Rankings for Week 12 Matchups

Best Overall Game

Chiefs vs Bills

Best Offensive Game

Chiefs vs Bills

Best Defensive Game

Broncos vs Steelers

Best Division Rivalry

Eagles vs Cowboys

Best Quarterback Battle

Patrick Mahomes vs Josh Allen

Best Rookie Showcase

Raiders vs Browns

Best Fantasy Matchup

Chiefs vs Bills

Best Live Betting Opportunity

Chiefs vs Bills

Best Same Game Parlay

Chiefs vs Bills

Best Thanksgiving Game

Chiefs vs Bills

Biggest Upset Alert

Broncos over Steelers

Lock of the Week

49ers over Seahawks

Thanksgiving Week is one of the busiest betting weekends of the NFL season. From early Thanksgiving kickoffs through Monday Night Football, YouWager.lv offers betting markets on every game, including point spreads, moneylines, player props, Same Game Parlays, teasers and live betting.

Frequently Asked Questions

When does NFL Week 12 start?

Week 12 begins on Wednesday, November 25, 2026, with the Green Bay Packers visiting the Los Angeles Rams.

Are there any bye weeks in Week 12?

No. Every NFL team plays during Thanksgiving Week.

What games are played on Thanksgiving?

Chicago Bears at Detroit Lions.

Philadelphia Eagles at Dallas Cowboys.

Kansas City Chiefs at Buffalo Bills.

What is the Black Friday game?

The Denver Broncos visit the Pittsburgh Steelers on Prime Video.

What is the Sunday Night Football game?

The New England Patriots visit the Los Angeles Chargers on NBC.

What is the Monday Night Football game?

The Carolina Panthers visit the Tampa Bay Buccaneers on ESPN.

Which Week 12 game is best for fantasy football?

Chiefs vs Bills projects as the top fantasy matchup because it features Patrick Mahomes, Josh Allen and multiple elite offensive playmakers.

Which Week 12 game is best for betting?

Chiefs vs Bills should generate the highest betting volume of Thanksgiving weekend because of its superstar quarterbacks, playoff implications and expanded betting markets available at YouWager.lv.

Where can I bet on every Week 12 NFL game?

You can bet every Week 12 matchup at YouWager.lv, including point spreads, moneylines, totals, player props, Same Game Parlays, teaser bets and live in-game wagering.

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