Chicago Cubs vs Pittsburgh Pirates MLB Prediction and Pick, Today's MLB Betting Picks, 7-25-2026

Chicago Cubs vs Pittsburgh Pirates MLB Prediction and Pick, 7-25-2026. Today’s MLB Betting Picks – Best available odds at YouWager.lv. Claim your signup bonus.

Our Chicago Cubs vs Pittsburgh Pirates Pick: PIRATES

Pittsburgh enters this matchup with the stronger overall profile, combining elite offensive production with a dominant pitching advantage. The Pirates have shown the ability to generate runs consistently, ranking second in MLB with 5.27 runs per game while producing more power and extra-base hits than Chicago. On the mound, Skenes gives Pittsburgh a major edge with his 2.36 career ERA, 0.974 WHIP, 2.30 FIP, and elite 5.24 strikeout-to-walk ratio against a Cubs staff that has struggled with a 4.27 ERA and 4.76 FIP. Meanwhile, Chicago’s bullpen issues create additional concerns. With the stronger starter and offensive production, Pittsburgh has the edge to secure the win.

MATCHUP	Cubs	Pirates
Chicago Cubs vs Pittsburgh Pirates Moneyline	-122	+102
Where	PNC Park in Pittsburgh, PA
When	Saturday, July 25, 2026

Chicago Cubs vs Pittsburgh Pirates MLB Prediction – 7-25-2026 – MLB Betting Picks

Here is our Chicago Cubs vs Pittsburgh Pirates MLB Prediction for both teams:

Chicago Cubs vs Pittsburgh Pirates MLB Prediction: Cubs Preview

Now in this Chicago Cubs vs Pittsburgh Pirates MLB Prediction, we have the Cubs preview.

The Chicago Cubs are now ranked fourth in baseball due to the fact that they are averaging 5.1 runs per game through their collective efforts. A total of 520 runs have been scored by them, and their on-base percentage is 0.338%. There have been 163 doubles hit by the Cubs as a team, and they have hit 128 balls out of the park by themselves. In addition to 853 base knocks, they have contributed 486 runs batted in to the team’s total through the course of this season, and their batting average is currently at.245. In addition to having a slugging percentage of.413, the Chicago Cubs have been called out on strikes 868 times, while they have drawn a walk 448 times at the plate.

The Cubs have a team earned run average of 4.27 thus far this season, which ranks 19th in Major League Baseball. Additionally, the Cubs’ pitching staff has struck out 798 batters. On average, Cubs pitchers have allowed 157 home runs and 455 total runs, which places them in the 12th spot in the league. Throughout the course of the season, their pitching staff has walked 311 batters, and their batting average per inning (FIP) has been 4.76. Chicago has allowed 845 hits, which is equivalent to 8.4 hits per nine innings, and 431 earned runs. The team’s pitching staff has a combined WHIP of 1.27, and their strikeout to walk ratio is currently at 2.57.

Three hundred thirty-six relief pitchers have been sent out to the mound by the Cubs thus far this season. Up to this point in the season, relievers have been given 152 runners to inherit, and 31.6% of those runners have ended up scoring. In the current season, the relief pitchers have a total of 36 holds, which places them 29th in the baseball league. There have been 104 instances in which Cubs pitchers have shown up to the mound with runners on base, and they have also made 99 appearances in high leverage situations. To this point in the year, they have made 20 saves, but out of the 37 opportunities they have had to make saves, they have failed to convert 17 of them. After entering the game in 79 different save situations, the Cubs relievers have a save percentage of 54.1% and have earned a save percentage.

Throughout the course of this season, the Chicago Cubs have posted a total of 2,725 putouts, in addition to 944 assists and 40 mistakes. They presently have a fielding percentage of.989, which places them in third place in the professional baseball league. Additionally, they have accomplished a total of 77 double plays. The Cubs are now in third place in Major League Baseball due to the fact that they have played 8,175 innings on the diamond and have converted 71.7% of balls in play into outs.

During his stint in the major leagues, Imanaga has faced 1,725 batters and has a career record of 30-19 wins and 19 losses. He has earned a fielding average of 3.40 and has earned a lifetime game record of 30-19. There have been 366 hits allowed against him, which is 7.6 hits per nine innings, and he has 82 free passes. The earned run average for him is 3.45, and he has allowed 166 earned runs overall. His WHIP is 1.035. There have been 433 innings pitched by Imanaga, and he has recorded 400 strikeouts during the course of his career.

Chicago Cubs vs Pittsburgh Pirates MLB Prediction by YouWager.lv.

Chicago Cubs vs Pittsburgh Pirates MLB Prediction: Pirates Preview

Next in this Chicago Cubs vs Pittsburgh Pirates MLB Prediction, we have the Pirates preview.

Therefore far this season, Pittsburgh has a total of 519 runs batted in and 132 long balls to their credit. At the same time that they have walked 382 times and scored 543 runs, they have also registered 164 doubles between them. During the first few games of the season, the Pittsburgh Pirates have a batting average of.261 and an on-base percentage of.339 respectively. In addition to having a slugging percentage of.424, the Pirates have a run average of 5.27 per game, which places them in second place in the league. They have a total of 933 base hits and have been rung up on 985 occasions, which is the most in the Major League Baseball.

The Pirates have a team WHIP of 1.309 and a FIP of 3.96 over the course of the season. This indicates that they have been successful as a unit throughout the course of the season. Their strikeouts to base hits ratio is 9.20, which means they have 943 strikeouts against 370 bases on balls. They have a total of 833 hits allowed by their pitching staff, which places them in fifteenth place in baseball rankings. They have allowed 107 home runs, and their average run rate per nine innings is 4.82, which places them 21st in the league. A total of 492 runs have been allowed to be scored against the Pittsburgh pitching staff this season, resulting in an earned run average of 4.26 (435 earned runs surrendered).

A total of 129 inherited base runners have been scored by Pittsburgh bullpen relievers, which results in an inherited scoring rate of 31.0%. During the course of their career, their relief pitchers have taken the mound 93 times in high leverage situations and 91 times while there were base runners on the bases. As a result of having 87 save situations, the Pirates have 47 holds and 19 saves that were not successful. During the course of the season, they have sent 327 bullpen pitchers to the hill, which places them in the 28th position in the league with a save percentage of 51.3%.

The Pirates have earned a defensive efficiency of 69.0% over the course of 8,271 innings played, which places them 24th in the professional baseball league. The fielding percentage of the Pittsburgh Pirates is.983, which places them 22nd in the major leagues. Additionally, the Pirates have turned 81 double plays. During the course of this season, the Pirates have accumulated a total of 2,757 putouts, contributed 811 assists, and committed 60 errors.

During his time in the Major League Baseball, Skenes has allowed 324 hits while striking out a total of 524 batters in 435 innings pitched. Over the course of his career, Skenes has compiled a record of 30-21, earning him a 2.36 earned run average while allowing 6.7 hits per nine innings pitched. With a WHIP of 0.974 and a FIP of 2.3, he has allowed a total of 114 earned runs to be scored against him via his pitching. Over the course of his career, he has faced 1,712 batters from opposing teams, and his strikeout-to-base ratio is 5.24.

Chicago Cubs vs Pittsburgh Pirates MLB Prediction by YouWager.lv.

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Chicago Cubs vs Pittsburgh Pirates MLB Prediction and Pick, 7-25-2026. MLB Betting Picks, by YouWagert.lv

Chicago Cubs vs Pittsburgh Pirates MLB Prediction and Pick, Today’s MLB Betting Picks, 7-25-2026