Pittsburgh Pirates vs New York Yankees MLB Prediction and Pick, Today's MLB Betting Picks, 7-22-2026

Pittsburgh Pirates vs New York Yankees MLB Prediction and Pick, 7-22-2026. Today’s MLB Betting Picks – Best available odds at YouWager.lv. Claim your signup bonus.

Our Pittsburgh Pirates vs New York Yankees Pick: PIRATES

Pittsburgh is the recommended pick in this matchup because the Pirates bring one of the hottest and most productive offenses in baseball into the game. They rank second in MLB at 5.3 runs per contest while hitting .263 as a team with a strong .341 on-base percentage, giving them a clear offensive edge over the Yankees. Although New York owns the superior pitching staff and Gerrit Cole is the more accomplished starter, Pittsburgh has consistently generated offense through both power and contact, making them capable of challenging elite pitching. Mitch Keller has been inconsistent over his career, but the Pirates’ lineup has the firepower to provide run support early. If Pittsburgh can force Cole into a higher pitch count and reach New York’s bullpen, their offensive depth gives them an opportunity to pull off the upset. With the stronger lineup and momentum at the plate, the value lies with the Pirates despite the Yankees’ advantage on the mound.

MATCHUP	Pirates	Yankees
Pittsburgh Pirates vs New York Yankees Moneyline	+102	-122
Where	Yankee Stadium in Bronx, NY
When	Wednesday, July 22, 2026

Pittsburgh Pirates vs New York Yankees MLB Prediction – 7-22-2026 – MLB Betting Picks

Here is our Pittsburgh Pirates vs New York Yankees MLB Prediction for both teams:

Pittsburgh Pirates vs New York Yankees MLB Prediction: Pirates Preview

Now in this Pittsburgh Pirates vs New York Yankees MLB Prediction, we have the Pirates preview.

In addition to having a batting average of.427, the Pittsburgh Pirates have been walked 376 times and have been rung up 956 in total. During the course of the season, they have a batting average of.263, in addition to receiving 923 base knocks and contributing 514 runs batted in. A total of 164 doubles have been hit by the Pirates as a team, and they have also knocked 130 balls out of the park. There have been 538 runs scored by them, and their on-base percentage is currently at.341. The Pittsburgh Pirates are currently in second place in the league with a team average of 5.3 runs scored per game. This puts them in a position of dominance.

Their pitching staff has a team WHIP of 1.32, and they have accumulated a K/BB ratio of 2.55 over the course of their career. The pitchers for the Pirates have allowed 106 home runs and 487 total runs, which places them in 23rd place in the league. 430 earned runs and 822 base hits have been allowed by Pittsburgh, which is equivalent to 8.2 per nine innings. On the season, the Pirates have a team earned run average of 4.30, which places them twenty-first in the league. Additionally, the Pirates’ pitching staff has struck out 925 batters. Through the first month of this year, they have walked 363 players from the opposing team, and their batting average as a unit is 3.98.

Three hundred twenty-two relief pitchers have been sent to the hill by the Pirates thus far this season. There have been 129 runners that have been inherited by the bullpen pitchers throughout the season, and 31.0% of those players have crossed home plate. This year, relief pitchers have recorded 47 holds, which places them 21st in Major League Baseball. In addition to having 92 appearances in high leverage situations, relief pitchers for the Pirates have entered the game 90 times with opponents already on base. They have made 19 saves for the year, but they have failed to save 18 of the 37 opportunities they have had to save the game. The relief pitchers for the Pirates have a save percentage of 51.4% and have entered the game in 85 different save situations.

Over the course of this season, the Pittsburgh Pirates have posted a total of 2,703 putouts, in addition to 798 assists and 60 errors. They have a total of 79 double plays, and their fielding percentage is currently at.983, which places them in 22nd place in the professional baseball league. Out of 8,109 innings played, the Pirates have converted 68.9% of baseballs in play into outs, which places them in the 24th spot in the Major League Baseball rankings.

During his time in the Major League Baseball, Keller has pitched for a total of 981 innings and has recorded 914 strikeouts. His earned run average is 4.58, and he has a WHIP of 1.376. He has also allowed 499 earned runs. In addition to 334 free passes, he has allowed 1,016 hits, which is equivalent to 9.3 hits per nine innings. Keller has amassed a career record of 48-72 and has a 4.51 earned run average (FIP) while facing 4,261 batters throughout his stint in the major leagues.

Pittsburgh Pirates vs New York Yankees MLB Prediction by YouWager.lv.

Pittsburgh Pirates vs New York Yankees MLB Prediction: Yankees Preview

Next in this Pittsburgh Pirates vs New York Yankees MLB Prediction, we have the Yankees preview.

In addition to 452 runs batted in, New York has a total of 146 home runs over the course of the previous year. In addition to scoring 475 runs and accumulating 150 doubles, they have also been awarded 375 free bases and have earned a total of 475 runs. The New York Yankees are currently in the midst of the season with a team on-base percentage of.316 and a batting average of.237. In Major League Baseball, the Yankees have a slugging percentage of.423, and they score 4.75 runs per game, which places them tenth. The number of times they have struck out is 899, which is fifth in MLB, and they have 784 hits on base.

The Yankees have a team WHIP of 1.193 and a team FIP of 3.76 so far this season. Additionally, the Yankees have a fielding percentage of 3.76. The ratio of their strikeouts to walks is 8.90, with 873 strikeouts and 302 walks respectively. As a baseball team, they are currently placed fourth in the league in terms of total hits allowed, with 756 for the season. The team has allowed 100 home runs, and they have allowed 3.93 runs per nine innings, which places them fifth in the league. Throughout the course of the season, the New York pitching staff has allowed 387 runs to be scored against them, while maintaining a team earned run average of 3.42 (337 earned runs surrendered).

They are currently ranked twenty-first in Major League Baseball with a save percentage of sixty percent, and they have sent three hundred thirty-two relievers to the mound so far this season. On 107 occasions, their bullpen pitchers have taken the mound in high leverage situations, and on 114 occasions, they have done so with runners on base. 49 of the Yankees’ save opportunities have been successful, while 16 of their saves have been missed. Pitchers from the New York bullpen have been called upon to take the mound in forty different save opportunities, and they have managed to pull off 24 saves. Out of the 169 base runners that they have inherited, the bullpen pitchers for the New York Yankees have an inherited scoring percentage value of 25.4%.

The New York Yankees have a fielding percentage of.984 and have made 72 double plays, which places them in twenty-first place among professional baseball teams. During the course of this season, the Yankees have accumulated a total of 2,663 putouts, 869 assists, and 57 errors respectively. The Yankees have earned a defensive efficiency of 71.0% over the course of 7,989 innings played, which places them seventh in the professional baseball league.

Throughout his career, Cole has a record of 156-85 wins and losses, has a 3.20 earned run average, and has allowed 7.5 hits per nine innings pitched. He has faced 8,091 hitters over the course of his career, and his strikeout-to-base ratio is 4.50. A WHIP of 1.091 and a FIP of 3.2 have been earned by him, and he has allowed 714 earned runs to be scored against him. In his career in the Major League Baseball, Cole has allowed 1,679 base hits while earning 2,306 strikeouts in a total of 2,009 innings pitched.

Pittsburgh Pirates vs New York Yankees MLB Prediction by YouWager.lv.

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Pittsburgh Pirates vs New York Yankees MLB Prediction and Pick, 7-22-2026. MLB Betting Picks, by YouWagert.lv

Pittsburgh Pirates vs New York Yankees MLB Prediction and Pick, Today’s MLB Betting Picks, 7-22-2026