Lions vs Commanders Prediction and Pick, Week 10

The Week 10 clash between the Detroit Lions and the Washington Commanders promises to be a high-stakes matchup that could have playoff implications for both teams. Historically, these two squads have had a competitive rivalry, with recent matchups showing a mix of wins on both sides, including a commanding 45-31 victory for Washington in Detroit earlier this year. Detroit has been one of the more explosive teams in the league, averaging over 30 points per game this season, while Washington has struggled for consistency, especially on the road. Both teams feature strong offensive weapons, but their defensive units will be tested in unique ways. Detroit’s offense ranks highly in points scored and rushing yards, while Washington relies heavily on its ground game and opportunistic defense. Special teams and turnovers could also play a pivotal role in deciding this game, as both squads have been able to capitalize on mistakes in recent weeks. Considering recent trends, key player performances, and head-to-head history, this game has all the ingredients of a fast-paced, high-scoring contest that could go down to the wire.

For the Lions, their offense has been firing on all cylinders, ranking third in the league in points scored while showing balance in both the passing and rushing games. Detroit’s ground attack, averaging over 130 rushing yards per game, will be a significant factor against a Washington defense that struggles to contain explosive runners. Quarterback play has been efficient, with relatively low turnovers despite a moderate passing attack, and Detroit has also excelled at controlling the clock, allowing them to wear down opposing defenses. The Lions’ offensive line has created solid running lanes while also protecting the quarterback enough to keep drives alive. Defensively, Detroit ranks well against the run but has shown vulnerability in pass coverage, which Washington may try to exploit. Momentum will be on Detroit’s side after a decisive 24-9 win over Tampa Bay last week, and the team’s ability to score in all four quarters gives them a high ceiling in this matchup. Expect the Lions to dictate tempo early and lean on their rushing attack to keep the Commanders’ defense off balance.

Washington, meanwhile, has had a rollercoaster season, with inconsistency in both offensive production and defensive execution. The Commanders’ strength lies in their rushing attack, which ranks among the league’s best, and they will need to lean on that against a Lions front that has been stout but not impenetrable. Passing efficiency has been modest, and Washington has struggled to protect the quarterback, giving up significant sacks in recent games. Defensively, the team excels in forcing turnovers but has been prone to giving up big plays, particularly against high-powered offenses like Detroit. Special teams could provide a difference-maker, as return yards have been a strong point for Washington and could set up scoring opportunities. The Commanders will need a complete game plan that balances run and pass, minimizes mistakes, and pressures the Lions’ quarterback to stand a chance. If they can control the clock and capitalize on turnovers, an upset is possible, but their inconsistency makes this a difficult task against a Lions team hitting its stride.

Lions vs Commanders Prediction: Head to Head

Date	Opponent	Score	Spread	Total	Moneyline
1/18/25	@DET	WAS 45-31	DET-8.5	O55.5	DET-550
9/18/22	@DET	DET 36-27	DET+1.0	O45.5	DET+135
11/15/20	@DET	DET 30-27	DET-4.0	O46.5	DET-210
11/24/19	@WAS	WAS 19-16	WAS+3.5	U40.5	WAS+162
10/23/16	@DET	DET 20-17	NL	NL	NL
8/20/15	@WAS	WAS 21-17	NL	NL	NL
9/22/13	@WAS	DET 27-20	NL	NL	NL
10/31/10	@DET	DET 37-25	NL	NL	NL
9/27/09	@DET	DET 19-14	NL	NL	NL
10/26/08	@DET	WAS 25-17	NL	NL	NL

Date	Opponent	Score	Spread	Total	Moneyline
10/27/25	@KC	L 28-7	L+3.5	U48.5	L+160
10/19/25	@DAL	L 44-22	L-2.5	O48.5	L-130
10/13/25	CHI	L 25-24	L-4.5	O48.5	L-205
10/05/25	@LAC	W 27-10	W+1.5	U47.5	W+102
9/28/25	@ATL	L 34-27	L-3.5	O48.5	L-175
9/21/25	LV	W 41-24	W-7.5	O47.5	W-340
9/11/25	@GB	L 27-18	L+1.5	U48.5	LEVEN
9/07/25	NYG	W 21-6	W-6.5	U45.5	W-350
1/26/25	@PHI	L 55-23	L+4.5	O47.5	L+188
1/18/25	@DET	W 45-31	W+8.5	O55.5	W+410

Lions vs Commanders Prediction: Detroit Offense

Lions vs Commanders Prediction: Washington Offense

Lions vs Commanders Prediction and Pick, Week 10, by YouWager.lv.