NFL Spreads Week 1 2025: Panthers vs Jaguars Betting Lines. Place a bet on this NFL football game with a 100% crypto football bonus.

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NFL Spreads Week 1 2025: Panthers vs Jaguars

The 2025 NFL season opens with a fascinating Sunday Night Football showdown between the Carolina Panthers and the Jacksonville Jaguars. The spread sits at Jacksonville -3, Carolina +3, with a total of 46. Oddsmakers give the Jaguars the slight edge at home, but this matchup is far from a lock either way.

Carolina comes into Week 1 on the heels of a late-season surge in 2024, where they went 7-2 overall down the stretch and pulled off some surprising upsets. They proved they could put points on the board, especially in December when they dropped 44 on Atlanta and 36 on Arizona. Their defense remained inconsistent, but their knack for forcing turnovers helped swing momentum in tight contests. Bettors will take note of Carolina’s poor road ATS record (2-15 in their last 17 away games), but also their strong head-to-head edge over Jacksonville, winning four of the last six meetings.

The Jaguars, meanwhile, had a frustrating close to their 2024 campaign. They lost six of their last eight, finishing 2-8 ATS in their final 10 games. Even when favored, Jacksonville went just 1-4 ATS, which raises caution for bettors looking to back them as a Week 1 favorite. Offensively, the Jaguars still have firepower, particularly at home, but defensive breakdowns were a persistent issue. Against passing offenses, Jacksonville allowed over 257 yards per game, ranking 32nd in the NFL.

When comparing team profiles, Carolina averaged just 187 passing yards per game in 2024, ranking 29th, which could mitigate Jacksonville’s defensive weakness. However, the Panthers had one of the better rushing units in the league, averaging 4.6 yards per carry, which may prove crucial against a Jaguars defense that surrendered over 132 rushing yards per game. If Carolina controls the ground game, they’ll shorten the clock and give themselves a chance to cover or even win outright.

For Jacksonville, the path to victory lies in outpacing Carolina offensively. The Jaguars averaged more plays per game and were more effective at sustaining drives. Playing at home under the lights, Jacksonville will rely on quick strikes through the air to exploit Carolina’s secondary. Still, given Jacksonville’s ATS struggles, bettors may prefer Carolina as the value play in Week 1.

This matchup shapes up as one of the most evenly balanced contests of opening weekend. With both teams looking to prove they can rebound from inconsistent 2024 campaigns, the betting angles—Carolina’s underdog value versus Jacksonville’s home edge—make this Sunday night clash must-watch football.

Panthers vs Jaguars Week 1 NFL Spreads 2025

Now in these Panthers vs Jaguars Betting Prediction, we have the Week 1 NFL Spreads 2025:

TEAM	SPREAD
Carolina	+3 ½
Jacksonville	-3 ½

NFL Spreads Week 1 2025: Favorite Prediction

The Jacksonville Jaguars enter Week 1 as the 3-point favorite over the Carolina Panthers, and while their ATS history is troubling, there’s still a strong case to back them as the favorite in this spot.

Jacksonville plays significantly better at home, and with a packed house for Sunday Night Football, the energy will be electric. The Jaguars’ offense has been up and down, but their ability to create explosive plays is undeniable. Last season, even during a tough stretch, they showed flashes of high-scoring potential, such as their 32-point outing against the Jets and a dominant 20-13 win over Tennessee. Against a Panthers defense that gave up 30+ points in five of their last eight games, Jacksonville has the opportunity to dictate tempo early.

The Jaguars also benefit from Carolina’s glaring road struggles. The Panthers have been dreadful away from home, going 2-15 ATS in their last 17 road games. For a team now traveling into one of the league’s more underrated environments, that trend is difficult to ignore. Jacksonville’s defense isn’t elite, but against a Panthers passing attack that ranked 29th in the NFL, they don’t need to be. Limiting Carolina’s big plays on the ground while forcing them into third-and-long situations is the key to controlling the game.

Statistically, Jacksonville has another edge: they simply run more plays. Averaging 66 plays per game to Carolina’s 58, the Jaguars control pace and maximize possession opportunities. In a game where every drive matters, that advantage could create separation on the scoreboard.

From a betting perspective, Jacksonville’s -3 spread is a modest ask for a team playing at home in primetime. The moneyline (-155) also provides value for bettors who want less risk and simply trust Jacksonville to handle business. While Carolina’s underdog case is compelling, especially given their late-season hot streak, the Jaguars have the structural advantages—home field, offensive tempo, and defensive matchups—that make them the stronger favorite.

NFL Spreads Week 1 2025: Underdog Prediction

While Jacksonville is favored, the Carolina Panthers are the more intriguing underdog bet in this matchup. Getting +3 on the spread and +135 on the moneyline, Carolina provides a combination of value and recent momentum that bettors can’t ignore.

Carolina finished the 2024 season with a 7-2 record in their last nine games, highlighted by wins over Atlanta, Arizona, and the Giants. During that stretch, they proved capable of scoring in bunches, twice topping 36 points. Their ability to create turnovers also gave them a fighting chance against top-tier opponents like Dallas and Philadelphia. That resilience is exactly what makes them appealing as an underdog.

The head-to-head history leans toward Carolina as well. The Panthers are 4-2 in their last six meetings with Jacksonville, including the memorable 2019 win where they put up 34 points. Even when the Jaguars were competitive, Carolina often managed to cover or win outright.

Jacksonville’s ATS woes amplify the value on Carolina. The Jaguars went 2-8 ATS in their last 10 games and struggled mightily against NFC competition, going 0-5 in their last five such matchups. They’ve also been unreliable as favorites, with a 1-4 ATS record in that role. For bettors, that trend is a red flag that makes Jacksonville difficult to back with confidence.

Carolina’s path to an upset lies in their rushing attack. Averaging 4.6 yards per carry last season, the Panthers were among the top 10 rushing units in the league. Against a Jaguars defense that surrendered over 132 rushing yards per game, the Panthers can establish control with a physical ground game. If they slow the tempo and keep Jacksonville’s offense off the field, Carolina has every chance to not only cover but also win outright.

The over/under at 46 also plays into Carolina’s favor. In six of their last seven games, the total has gone over, suggesting that if this becomes a shootout, the Panthers can hold their own. Bettors who believe in the underdog storyline will like the +135 moneyline, especially paired with sportsbook bonuses that double crypto deposits.

Panthers vs Jaguars Betting Lines: Moneyline and Total

Now on this article on NFL Spreads Week 1 2025, we also have the other two Panthers vs Jaguars betting lines, moneyline and total:

Panthers vs Jaguars Betting Lines: Moneyline

TEAM	MONEYLINE
Carolina	+160
Jacksonville	-180

Panthers vs Jaguars Betting Lines: Total

OVER / UNDER
47 O
47 U

NFL Spreads Week 1 2025: Survivor Pool Picks

Now in this article on NFL Spreads Week 1 2025, we have the best Week 1 NFL survivor pool picks:

NFL Spreads Week 1 2025 Survivor Pool Picks: Denver Broncos

The Denver Broncos are going to be the very first official pick from the pool of survivors. They are the most eagerly awaited team during the first week, and for a very good reason. Tennessee has issues on both offense and defense, and they did not obtain enough new players over the off-season to boost their prospects of competing against a team like Denver. The Broncos have their sights set on winning the Super Bowl this season, and in order to accomplish this goal, they must focus on shutting down Cam Ward, a rookie quarterback. Bo Nix will make an absolutely spectacular impression in the first game of his sophomore season, and it is beyond comprehension that the Broncos will suffer a defeat on their own turf any time soon. Despite the fact that this is going to be a square and a popular pick this week, there are instances when this is the most appropriate option. We have an abundance of time to deviate from the standard approach, and there is no reason to be polite because every single one of the entries is still in existence.

NFL Spreads Week 1 2025 Survivor Pool Picks: Washington Commanders

The New York Giants have no chance at all of overcoming the Washington Commanders in the first week. It is often a good idea to steer clear of divisional games when participating in survival pools. Jayden Daniels gained notoriety for his contributions to Washington during the season that had just finished, and the team he plays for has achieved even more success than it did in the year before. There is a possibility that the Commanders will not be able to replicate the fantastic season that they experienced in the year prior; however, they will have the opportunity to start off the season with a win that will make them feel good in front of their home crowd.

NFL Spreads Week 1 2025 Survivor Pool Picks: Arizona Cardinals 

This season, one of the most popular techniques will be to place a bet against the New Orleans Saints, and even a team that is not extremely strong, such as the Cardinals, can make this appear to be an easy bet. A breakout season from Kyler Murray has not been seen in quite some time, and there is a possibility that one will never occur. Both Tyler Shough and Spencer Rattler have proven to be disappointing players; meanwhile, Murray has failed to meet the expectations that people have set for him. The New Orleans Saints are experiencing a lack of youthful promise as well as financial difficulties. The team is also in danger of finishing the season with a winless record of 0–17. If you are looking to steer clear of the Broncos, this is not a terrible option considering Arizona does not have many games on their schedule that are less challenging than this one.

NFL Spreads Week 1 2025 Survivor Pool Picks: Kansas City Chiefs

Patrick Mahomes and his teammates are not going to let the humiliating defeat that the Kansas City Chiefs suffered in the Super Bowl the previous season prevent them from utterly annihilating the Los Angeles Chargers. The Chiefs have outperformed the Chargers in recent years, but there is always a chance that the international twist will throw a curveball into this matchup. Despite this, making use of the Chiefs in week one is not a smart strategy due to the fact that there are other options accessible that are safer.

NFL Spreads Week 1 2025 Survivor Pool Picks: New England Patriots 

When it comes to this game, there are many reasons to feel hopeful about the Patriots. It is a possibility that Geno Smith may need a certain amount of time to become accustomed to a new offense because Drake Maye has been performing increasingly well with each appearance that he has made on the field. On top of that, the defensive advantages of the Patriots will make making the switch even more challenging than it would be otherwise. New England will maintain a large edge in the game as a consequence of the fact that this will be a game in which scores will be low and inches will play a significant role. Be on the side of the Patriots to win the game, since they are the selection of the week and are going up against the common consensus. They are the squad to go with if you are looking to cause an upset in Week 1.

NFL Spreads Week 1 2025 Survivor Pool Picks: Indianapolis Colts

The Indianapolis Colts are going to begin the season by putting Daniel Jones in the game during the first week, which is very unexpected. Anthony Richardson is a talented young athlete, and Jones is a reliable starter in the National Football League. However, this is a controversial decision to make with the future in mind. At the moment, there are serious issues on both sides of the ball, in the locker room, and in pretty much every other part of the Dolphins’ organization. The entire field is plagued by these issues that are impacting the Dolphins. The Colts have a slight edge in every position, which will be enough to secure a win on their home turf. The team’s morale would surely improve if they were able to achieve a positive result in the first week, but the Colts perform better as a whole.

NFL Spreads Week 1 2025 Survivor Pool Picks: Philadelphia Eagles 

This is what the best course of action to avoid throughout this week is to avoid. The Eagles are going to have a difficult time if they go up against a Cowboys club that is desperate to win in the Super Bowl. Dallas is going to be far better than the majority of people anticipate this season, and I would not be in the slightest bit surprised if they were victorious over the team that is now in the championship. This game is going to be much closer to a tie than the spread implies it would be due to the fact that the Cowboys are one of the few teams that have the ability to match the kind of physicality that the Eagles bring to the field. That being stated, the Eagles continue to be a really powerful group, and they will most likely discover a method to achieve their goals.

NFL Spreads Week 1 2025 Survivor Pool Picks: Pittsburgh Steelers

What kind of image will Aaron Rodgers project to the general public if he joins the Steelers? I expect that the future Hall of Famer will have a better beginning to his game than he did two years ago in his first game with the Jets, which will give him the opportunity to thrive. His defense is adequate enough for him to achieve success. It would seem that the only viable alternative for New York is to deploy quarterback Justin Fields, but he would appear to be completely powerless when he is up against a powerful defense like the one that belongs to the Steelers.

NFL Spreads Week 1 2025 Survivor Pool Picks: Chicago Bears

This Monday night is the last night of Week 1 for both the Bears and the Vikings, and this week, Chicago is a fantastic team to go after. Following a year spent on the bench, the Minnesota team is uncertain about the performance they can expect from JJ McCarthy. On the other hand, Caleb Williams demonstrated remarkable skills in primetime games throughout the previous season. Over the course of the offseason, the Chicago Bears made a number of modifications on both sides of the ball. The Minnesota Vikings will have big hurdles as a result of the improved defense that Chicago has put together. Even if there are options available that are more secure, I would not be surprised if you choose to go with the Bears this week.

NFL Spreads Week 1 2025 Survivor Pool Picks: Cincinnati Bengals

Divisional matchups have their own unique obstacles, but when these games are played against a team like the Browns, those problems are multiplied. Joe Burrow and the Bengals, on the other hand, are running out of time to deliver results that can be quantified, while Cleveland is not under any pressure to start the season. When they take on the field, it is going to be a filthy and slow game for Cleveland, and it is going to be an uphill battle for the team who plays them because the Browns are a strong team. What are the chances that the Bengals will come out on top in this game? That is true. Will you be putting the safety of those who survived squarely on their shoulders? There is no question about that.

NFL Spreads Week 1 2025 Survivor Pool Picks: Los Angeles Rams

This game will carry a great deal of importance for the playoffs at an early stage in the season due to the fact that both of these clubs are seen as underdogs this year. Even if it is very probable that CJ Stroud will make a recovery from the sophomore slump that he encountered in the previous year, it is impossible to overlook Matthew Stafford and the team of athletes that are members of the Rams. The Rams have just finished retooling an offensive unit that was already incredibly powerful in order to make it even more effective. They are now able to score thirty or more points at home with ease.

NFL Spreads Week 1 2025 Survivor Pool Picks: Atlanta Falcons

Atlanta will have the benefit of playing at home for this divisional match-up in Georgia, and they will be able to put their minds to it and come out on top. The Tampa Bay club has a wide variety of offensive skills to pick from; nevertheless, their lack of run stoppers will present Bijan Robinson with a wealth of opportunity to succeed. The Falcons will have lost the game in the second half if Michael Penix Jr. is able to provide them with the opportunity to grab the lead.

NFL Spreads Week 1 2025 Survivor Pool Picks: Green Bay Packers

We would most likely be betting on the Lions if this clash were to occur later on in the year. There is a chance that some misunderstandings could arise with the new coaching staff, despite the fact that Detroit have superior skills on the field. Green Bay will be competing on the intimidating turf of Lambeau Field, and they have a far higher degree of continuity from the previous season than the Lions. This squad is normally a poor choice for betting, despite the fact that there is a tiny tilt in favor of the Packers.

NFL Spreads Week 1 2025 Survivor Pool Picks: Seattle Seahawks

Sam Darnold will be given the opportunity to join the Seattle Seahawks after the team made the decision to trade Geno Smith, a move that is expected to yield a favorable return during the opening week of the season. Despite the fact that the 49ers are a team that ended the previous season with a record of seven defeats and one win, it is challenging to bet against them at any point during the current season. They have not yet come anywhere near to being in good health, and they are also dealing with the matter of suspensions. The Seattle Seahawks also have the advantage of playing this game at home, and they are up against a difficult schedule this season.

NFL Spreads Week 1 2025 Survivor Pool Picks: Jacksonville Jaguars

It would be unwise for any individual who has survived the pool to jeopardize their safety by taking part in any of these dumpster fires at this stage in the season. At this moment in time, none of these cats can be considered dependable options, but later in the season, one of them could emerge as a halfway decent alternative.

NFL Spreads Week 1 2025 Survivor Pool Picks: Baltimore Ravens

There is no way to even think about putting these two teams in a matchup that is this close to one another considering the fact that both of them are among the best in the league. If you choose to assume one of the positions during the first week in the survivor pool, you must make certain that you are aware with all of its regulations.

 

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