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NFL Spreads Week 1 2025: Dolphins vs Colts

he 2025 NFL season kicks off with a marquee Sunday Night Football matchup between the Miami Dolphins and Indianapolis Colts, and the betting markets couldn’t be tighter. With the Colts listed at -1.5 and Miami at +105 on the moneyline, oddsmakers expect a razor-close game that could swing either way. The Over/Under is set at 47, right in the middle of the board, reflecting the balance between Miami’s disciplined, ball-control approach and Indy’s ability to turn contests into shootouts.

Head-to-head, the Colts have historically had the upper hand, winning eight of the last ten against Miami against the spread. However, those numbers don’t tell the full story. When playing in Indianapolis, the Dolphins have covered nine of their last eleven visits, suggesting the market often undervalues them on the road in this matchup. Miami also boasts a 4-1 ATS record in its last five Week 1 games, a key trend that gives them confidence heading into the opener.

Miami’s recent form is another encouraging sign for backers. The Dolphins won six of their final nine games last season, relying on efficiency, defensive resilience, and an ability to control time of possession. They ranked fourth in the league in average time on the field, keeping opposing offenses off balance. However, their ATS struggles against the Colts (2-8 in their last ten meetings) remain a concern for anyone backing them blindly.

For Indianapolis, the biggest storyline is their shaky Week 1 history. The Colts have failed to cover in their last eleven season openers, going 0-10-1 ATS. Still, they come into this game with home-field advantage and an offense that showed explosive potential late in 2024. While their defense surrendered more than 25 points per game and ranked among the league’s worst against the pass, their offensive upside, particularly in fourth quarters, makes them a dangerous favorite in any close spread.

This is the type of matchup that bettors love: conflicting trends, strength-versus-weakness matchups, and a spread small enough to make the moneyline a serious consideration. Miami’s ability to control the pace against Indy’s leaky defense could tilt the game in their favor, but Indianapolis’ late-game scoring punch and home crowd could swing it back. With everything so evenly matched, this is a true coin flip, which means bettors will want to dig deep into the favorite vs. underdog angles before deciding which way to lean.

Dolphins vs Colts Week 1 NFL Spreads 2025

Now in these Dolphins vs Colts Betting Prediction, we have the Week 1 NFL Spreads 2025:

TEAM	SPREAD
Miami	PK
Indianapolis	PK

NFL Spreads Week 1 2025: Favorite Prediction

If you’re looking to back a favorite in Week 1, the Indianapolis Colts -1.5 are the play. While it’s only a slim line, oddsmakers are signaling faith in the Colts’ home-field advantage and offensive potential. Indianapolis has been tough on AFC East opponents historically, going 8-2 in their last ten games against the division, and that includes multiple wins over Miami.

The key factor for Indianapolis as the favorite is their offensive firepower. In 2024, they averaged strong second- and fourth-quarter scoring, often pulling away late in games. Against Miami’s disciplined but not overly explosive defense, the Colts’ ability to stretch the field could be the deciding factor. Despite allowing big plays defensively, Indy consistently found ways to stay competitive with high-scoring opponents. That late-game edge gives them value as a small favorite.

Miami backers will argue that the Colts’ 0-10-1 ATS record in their last 11 Week 1 games is too concerning to ignore. And yes, that trend is glaring. But it’s also an outlier that doesn’t necessarily reflect this roster’s current makeup. The Colts have upgraded their offensive balance, and being at home in primetime gives them a chance to break the curse.

Another reason to trust Indianapolis as the favorite is Miami’s inconsistency against the Colts. The Dolphins are just 2-8 ATS in their last ten head-to-head meetings, and although they’ve done well in Indy historically, that may not be enough to outweigh the Colts’ overall matchup advantage.

With such a tight spread, this play essentially comes down to whether you believe Indianapolis can win outright. At -1.5, it’s less about margin and more about securing victory. Given Miami’s reliance on ball control and defense, if the Colts’ offense gets rolling, they’re the more likely side to deliver. For Week 1 favorites, Indianapolis -1.5 is the sharp but cautious bet.

NFL Spreads Week 1 2025: Underdog Prediction

On the flip side, Miami +1.5 (+105 ML) is an excellent underdog option in Week 1. The Dolphins enter this matchup with momentum, having won six of their final nine games last season and posting a strong 4-1 ATS record in their last five Week 1 contests. Early-season form matters, and Miami has shown they can be trusted in openers.

The Dolphins’ best case as underdogs lies in their ability to exploit Indianapolis’ weak defense. The Colts ranked in the bottom tier against the pass, giving up nearly 230 yards per game through the air. Miami, while not a deep-strike offense, is efficient and consistent with short-to-intermediate passing. Combine that with their top-five ranking in time of possession, and Miami has the tools to grind out long drives that keep Indy’s offense on the sideline.

The historical trends are conflicting, but Miami’s 9-2 ATS record in their last 11 trips to Indianapolis is especially compelling. It shows that even when the Colts have been favored, the Dolphins often find ways to keep games tight or steal wins on the road. With such a small spread, the smarter play may even be taking the moneyline at +105 rather than relying on the +1.5 cushion.

Defensively, Miami also matches up well. They’ve leaned UNDER in many road games, and their discipline could frustrate Indianapolis, who thrives on late scoring bursts. If the Dolphins’ pass rush can apply pressure and force mistakes, their ball-control strategy could be enough to tilt the balance.

For underdog bettors, this is exactly the type of value spot you look for: a team with solid road history, a favorable matchup against a shaky defense, and plus odds on the moneyline. Miami may not be the safer play, but they’re the sharper side for Week 1 underdog bettors.

Dolphins vs Colts Betting Lines: Moneyline and Total

Now on this article on NFL Spreads Week 1 2025, we also have the other two Dolphins vs Colts betting lines, moneyline and total:

Dolphins vs Colts Betting Lines: Moneyline

TEAM	MONEYLINE
Miami	N/A
Indianapolis	N/A

Dolphins vs Colts Betting Lines: Total

OVER / UNDER
46 O
46 U

NFL Spreads Week 1 2025: Survivor Pool Picks

Now in this article on NFL Spreads Week 1 2025, we have the best Week 1 NFL survivor pool picks:

NFL Spreads Week 1 2025 Survivor Pool Picks: Denver Broncos

The Denver Broncos are going to be the very first official pick from the pool of survivors. They are the most eagerly awaited team during the first week, and for a very good reason. Tennessee has issues on both offense and defense, and they did not obtain enough new players over the off-season to boost their prospects of competing against a team like Denver. The Broncos have their sights set on winning the Super Bowl this season, and in order to accomplish this goal, they must focus on shutting down Cam Ward, a rookie quarterback. Bo Nix will make an absolutely spectacular impression in the first game of his sophomore season, and it is beyond comprehension that the Broncos will suffer a defeat on their own turf any time soon. Despite the fact that this is going to be a square and a popular pick this week, there are instances when this is the most appropriate option. We have an abundance of time to deviate from the standard approach, and there is no reason to be polite because every single one of the entries is still in existence.

NFL Spreads Week 1 2025 Survivor Pool Picks: Washington Commanders

The New York Giants have no chance at all of overcoming the Washington Commanders in the first week. It is often a good idea to steer clear of divisional games when participating in survival pools. Jayden Daniels gained notoriety for his contributions to Washington during the season that had just finished, and the team he plays for has achieved even more success than it did in the year before. There is a possibility that the Commanders will not be able to replicate the fantastic season that they experienced in the year prior; however, they will have the opportunity to start off the season with a win that will make them feel good in front of their home crowd.

NFL Spreads Week 1 2025 Survivor Pool Picks: Arizona Cardinals 

This season, one of the most popular techniques will be to place a bet against the New Orleans Saints, and even a team that is not extremely strong, such as the Cardinals, can make this appear to be an easy bet. A breakout season from Kyler Murray has not been seen in quite some time, and there is a possibility that one will never occur. Both Tyler Shough and Spencer Rattler have proven to be disappointing players; meanwhile, Murray has failed to meet the expectations that people have set for him. The New Orleans Saints are experiencing a lack of youthful promise as well as financial difficulties. The team is also in danger of finishing the season with a winless record of 0–17. If you are looking to steer clear of the Broncos, this is not a terrible option considering Arizona does not have many games on their schedule that are less challenging than this one.

NFL Spreads Week 1 2025 Survivor Pool Picks: Kansas City Chiefs

Patrick Mahomes and his teammates are not going to let the humiliating defeat that the Kansas City Chiefs suffered in the Super Bowl the previous season prevent them from utterly annihilating the Los Angeles Chargers. The Chiefs have outperformed the Chargers in recent years, but there is always a chance that the international twist will throw a curveball into this matchup. Despite this, making use of the Chiefs in week one is not a smart strategy due to the fact that there are other options accessible that are safer.

NFL Spreads Week 1 2025 Survivor Pool Picks: New England Patriots 

When it comes to this game, there are many reasons to feel hopeful about the Patriots. It is a possibility that Geno Smith may need a certain amount of time to become accustomed to a new offense because Drake Maye has been performing increasingly well with each appearance that he has made on the field. On top of that, the defensive advantages of the Patriots will make making the switch even more challenging than it would be otherwise. New England will maintain a large edge in the game as a consequence of the fact that this will be a game in which scores will be low and inches will play a significant role. Be on the side of the Patriots to win the game, since they are the selection of the week and are going up against the common consensus. They are the squad to go with if you are looking to cause an upset in Week 1.

NFL Spreads Week 1 2025 Survivor Pool Picks: Indianapolis Colts

The Indianapolis Colts are going to begin the season by putting Daniel Jones in the game during the first week, which is very unexpected. Anthony Richardson is a talented young athlete, and Jones is a reliable starter in the National Football League. However, this is a controversial decision to make with the future in mind. At the moment, there are serious issues on both sides of the ball, in the locker room, and in pretty much every other part of the Dolphins’ organization. The entire field is plagued by these issues that are impacting the Dolphins. The Colts have a slight edge in every position, which will be enough to secure a win on their home turf. The team’s morale would surely improve if they were able to achieve a positive result in the first week, but the Colts perform better as a whole.

NFL Spreads Week 1 2025 Survivor Pool Picks: Philadelphia Eagles 

This is what the best course of action to avoid throughout this week is to avoid. The Eagles are going to have a difficult time if they go up against a Cowboys club that is desperate to win in the Super Bowl. Dallas is going to be far better than the majority of people anticipate this season, and I would not be in the slightest bit surprised if they were victorious over the team that is now in the championship. This game is going to be much closer to a tie than the spread implies it would be due to the fact that the Cowboys are one of the few teams that have the ability to match the kind of physicality that the Eagles bring to the field. That being stated, the Eagles continue to be a really powerful group, and they will most likely discover a method to achieve their goals.

NFL Spreads Week 1 2025 Survivor Pool Picks: Pittsburgh Steelers

What kind of image will Aaron Rodgers project to the general public if he joins the Steelers? I expect that the future Hall of Famer will have a better beginning to his game than he did two years ago in his first game with the Jets, which will give him the opportunity to thrive. His defense is adequate enough for him to achieve success. It would seem that the only viable alternative for New York is to deploy quarterback Justin Fields, but he would appear to be completely powerless when he is up against a powerful defense like the one that belongs to the Steelers.

NFL Spreads Week 1 2025 Survivor Pool Picks: Chicago Bears

This Monday night is the last night of Week 1 for both the Bears and the Vikings, and this week, Chicago is a fantastic team to go after. Following a year spent on the bench, the Minnesota team is uncertain about the performance they can expect from JJ McCarthy. On the other hand, Caleb Williams demonstrated remarkable skills in primetime games throughout the previous season. Over the course of the offseason, the Chicago Bears made a number of modifications on both sides of the ball. The Minnesota Vikings will have big hurdles as a result of the improved defense that Chicago has put together. Even if there are options available that are more secure, I would not be surprised if you choose to go with the Bears this week.

NFL Spreads Week 1 2025 Survivor Pool Picks: Cincinnati Bengals

Divisional matchups have their own unique obstacles, but when these games are played against a team like the Browns, those problems are multiplied. Joe Burrow and the Bengals, on the other hand, are running out of time to deliver results that can be quantified, while Cleveland is not under any pressure to start the season. When they take on the field, it is going to be a filthy and slow game for Cleveland, and it is going to be an uphill battle for the team who plays them because the Browns are a strong team. What are the chances that the Bengals will come out on top in this game? That is true. Will you be putting the safety of those who survived squarely on their shoulders? There is no question about that.

NFL Spreads Week 1 2025 Survivor Pool Picks: Los Angeles Rams

This game will carry a great deal of importance for the playoffs at an early stage in the season due to the fact that both of these clubs are seen as underdogs this year. Even if it is very probable that CJ Stroud will make a recovery from the sophomore slump that he encountered in the previous year, it is impossible to overlook Matthew Stafford and the team of athletes that are members of the Rams. The Rams have just finished retooling an offensive unit that was already incredibly powerful in order to make it even more effective. They are now able to score thirty or more points at home with ease.

NFL Spreads Week 1 2025 Survivor Pool Picks: Atlanta Falcons

Atlanta will have the benefit of playing at home for this divisional match-up in Georgia, and they will be able to put their minds to it and come out on top. The Tampa Bay club has a wide variety of offensive skills to pick from; nevertheless, their lack of run stoppers will present Bijan Robinson with a wealth of opportunity to succeed. The Falcons will have lost the game in the second half if Michael Penix Jr. is able to provide them with the opportunity to grab the lead.

NFL Spreads Week 1 2025 Survivor Pool Picks: Green Bay Packers

We would most likely be betting on the Lions if this clash were to occur later on in the year. There is a chance that some misunderstandings could arise with the new coaching staff, despite the fact that Detroit have superior skills on the field. Green Bay will be competing on the intimidating turf of Lambeau Field, and they have a far higher degree of continuity from the previous season than the Lions. This squad is normally a poor choice for betting, despite the fact that there is a tiny tilt in favor of the Packers.

NFL Spreads Week 1 2025 Survivor Pool Picks: Seattle Seahawks

Sam Darnold will be given the opportunity to join the Seattle Seahawks after the team made the decision to trade Geno Smith, a move that is expected to yield a favorable return during the opening week of the season. Despite the fact that the 49ers are a team that ended the previous season with a record of seven defeats and one win, it is challenging to bet against them at any point during the current season. They have not yet come anywhere near to being in good health, and they are also dealing with the matter of suspensions. The Seattle Seahawks also have the advantage of playing this game at home, and they are up against a difficult schedule this season.

NFL Spreads Week 1 2025 Survivor Pool Picks: Jacksonville Jaguars

It would be unwise for any individual who has survived the pool to jeopardize their safety by taking part in any of these dumpster fires at this stage in the season. At this moment in time, none of these cats can be considered dependable options, but later in the season, one of them could emerge as a halfway decent alternative.

NFL Spreads Week 1 2025 Survivor Pool Picks: Baltimore Ravens

There is no way to even think about putting these two teams in a matchup that is this close to one another considering the fact that both of them are among the best in the league. If you choose to assume one of the positions during the first week in the survivor pool, you must make certain that you are aware of all of its regulations.

 

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