49ers vs Cardinals Betting Trends, Prediction, NFL Week 18. The game is set for Sunday, January 5th, 2025. Place a bet on this NFL football game now.

Visit our California Betting and Arizona Betting pages for more information.

49ers vs Cardinals Betting Odds

Here are the 49ers vs Cardinals Betting Odds:

TEAM	SPREAD	MONEYLINE	TOTAL
49ERS	+4.5	+180	42.5 O
CARDINALS	-4.5	-220	42.5 U

49ers vs Cardinals Betting Trends

Here are the 49ers vs Cardinals Betting trends for both teams, but first, we have the head-to-head for both teams:

49ers vs Cardinals Betting Trends: Head-to-Head

Now in these 49ers vs Cardinals Betting trends, we have the head-to-head stats:

49ers vs Cardinals Betting Trends: San Francisco

These are the 49ers vs Cardinals Betting trends for San Francisco:

• The over/under record for San Francisco’s last eight games is 1-7.
• Out of San Francisco’s last six games, the total has been over in four of those games.
• In their last seven games, San Francisco has a record of 1-6 against the spread.
• After five games versus Arizona, San Francisco has a record of 4-1 against the spread.
• San Francisco has a head-to-head record of 4-1 versus Arizona in their previous five games.
• In their previous five games played away from home, San Francisco has a record of 1-4 against the spread.
• On the road against Arizona, San Francisco has a winning record of 4-1 in their previous five games against the Arizona Cardinals.
• In their last six games against opponents from the National Football Conference, San Francisco has a record of 1-5 against the spread versus the opponent.
• In their last five games against teams from the National Football Conference West division, San Francisco has a record of 1-4 in terms of their overall performance.

49ers vs Cardinals Betting Trends: San Francisco Player Prop Facts

Now in these 49ers vs Cardinals Betting trends, we have the player prop facts for San Francisco:

• In three of his last four Sunday outings, Russell Gage has scored the last touchdown for his club, which took the underdog position in each of those games.
• During his last six games with the 49ers, Deebo Samuel has recorded more than 58 receiving yards in each of those games, even though the 49ers were underdogs against NFC West opponents.
• During his last six games with his squad, Joshua Dobbs has scored a touchdown in each of those games, even though his team was the underdog.
• All five of Deebo Samuel’s most recent performances with the 49ers, who are considered to be underdogs on the West Coast, have resulted in him rushing for more than thirteen yards.
• Over the course of his last five Sunday away games, Brock Purdy has thrown for more than 292 yards in four of those games.
• During his last five games with the 49ers, Deebo Samuel has racked up more than 71 yards rushing and receiving in each of those games, even though the 49ers were the underdogs against NFC West opponents.
• Over the course of his last six Sunday regular season road appearances, Brock Purdy has completed more than 22 passes in five of those games.
• As we head into Week 18, Jauan Jennings has tied for the record for the most receiving touchdowns in a single game throughout the course of this season with three touchdowns scored against the Rams in Week 3.

49ers vs Cardinals Betting Trends: Arizona

These are the 49ers vs Cardinals Betting trends for Arizona:

• All-time, Arizona has a record of 7-3 in their last 10 games.
• In their last six games, Arizona has a record of 1-5 against the spread.
• All five of Arizona’s most recent six games versus San Francisco have resulted in the total going over.
• In their previous five games played at home, Arizona has a record of 4-1 against the spread.
• In their last five games versus San Francisco, Arizona has a record of 1-4 on the road against the San Francisco 49ers.
• In their last five games versus a team from the National Football Conference, Arizona has a losing record of 0-5 in terms of their overall performance.
• When Arizona has played an opponent from the National Football Conference West division, they have a record of 5-15 against the spread in their last 20 games.
• There have been five of Arizona’s last seven games played in January that have resulted in the total going UNDER.
• During the last five games that Arizona has played as the underdog, the total has gone UNDER in four of those contests.

49ers vs Cardinals Betting Trends: Arizona Player Prop Facts

Now in these 49ers vs Cardinals Betting trends, we have the player prop facts for Arizona:

• Within the past six day games that the Cardinals have played against teams that have a losing record, James Conner has scored at least one touchdown in each of those games.
• Each of Trey Benson’s last six appearances has resulted in him accumulating more than 15 yards on the ground.
• After the Cardinals suffered a defeat on the road, Kyler Murray has thrown for more over 232 yards in seven of the previous eight games that the team has played.
• During the Cardinals’ most recent six home games, James Conner has accumulated more than 113 yards rushing and receiving in each of those games.
• During the Cardinals’ last eight home games against National Football Conference opponents, Elijah Higgins has recorded 11 or more receiving yards in seven of those games.
• Over the course of his last 11 home games against NFC West opponents, Kyler Murray has completed more than 22 passes in ten of those games.
• There is only one more interception that Jalen Thompson needs to make in his career.

49ers vs Cardinals Betting Prediction

Now, we have the 49ers vs Cardinals Betting prediction for both teams.

49ers vs Cardinals Betting Prediction: San Francisco

This is the 49ers vs Cardinals Betting prediction for San Francisco.

Currently holding a record of 6-10, the San Francisco 49ers have suffered three consecutive defeats, the most recent of which being a 40-34 setback to the Lions in week 17. Despite being 3.5 points underdogs, San Francisco was unable to capitalize on the fact that they were playing at home and also failed to cover the spread. The 49ers scored 74 points in total, comfortably surpassing the 50-point line, making this their second consecutive game in which they scored more than 50 points.

Our power rankings have the 49ers ranked eighth heading into week 18, despite the fact that they have a score margin of -1.5. Against the spread, they have a record of 5-11 and have suffered three consecutive losses. The likelihood of San Francisco either making the playoffs or winning the NFC West is a whopping 0.00 percent.

Our offensive power rankings have the 49ers ranked 12th heading into week 18, with an average of 22.8 points per game, which places them 13th in the National Football League. They are fifth in the league in terms of yards per game (372.6) and fourth in terms of passing yards per game (246), despite the fact that they rank twenty-fourth in terms of passing attempts. On the ground, San Francisco takes the fourteenth spot in terms of rushing attempts and the eleventh spot in terms of rushing yards per game (126.6). They have a three-down conversion rate of 42.9%, which places them ninth in the National Football League, and they have a red zone conversion percentage of 23rd.

During the seventeenth week of the season, Brock Purdy completed 27 of 35 throws for a total of 377 yards and three touchdowns. However, he also produced two interceptions. On the other hand, Isaac Guerendo recorded 34 rushing yards on 9 carries, while Ricky Pearsall led the club with 8 receptions for 141 yards and a score. During their game against the Lions, San Francisco was successful in scoring on all five of their trips into the red zone and converted 62.5% of their third-down attempts.

The 49ers’ defense allowed 287 passing yards and 26 completions during their game against the Lions, which they lost by a score of 40-34. During the game, the 49ers allowed the Lions to complete 76.5% of their throws and allowed them to score three touchdowns through the passing game. The 49ers surrendered 152 yards of rushing on 33 tries, with Detroit average 4.6 yards per attempt. The 49ers allowed this to happen on the ground. In addition, San Francisco had difficulty converting on third downs, which resulted in the Lions converting 64.3% of their tries on third down. It is true that the 49ers recorded two sacks during the game.

49ers vs Cardinals Betting: San Francisco Injury Report

Pos	Player	Status
WR	Deebo Samuel (Ribs)	Out
TE	George Kittle (Ankle)	Questionable
QB	Brock Purdy (Elbow)	Out
OL	Aaron Banks (Knee)	Out
DE	Robert Beal (Ankle)	Out
OL	Spencer Burford (Calf)	Out
LB	Dre Greenlaw (Calf)	Out
OL	Colton McKivitz (Knee)	Questionable
S	Ji’Ayir Brown (Ankle)	Questionable
CB	Charvarius Ward (Rest)	Questionable
RB	Isaac Guerendo (Hamstring)	Questionable
DE	Robert Beal (Ankle)	Questionable
RB	Isaac Guerendo (Hamstring)	Out
DE	Nick Bosa (Hip)	Questionable
OL	Ben Bartch (Ankle)	Out
DT	Khalil Davis (Knee)	Questionable
LB	Dre Greenlaw (Achilles)	Questionable
S	Malik Mustapha (Chest)	Out
RB	Isaac Guerendo (Foot)	Questionable
S	Talanoa Hufanga (Wrist)	Questionable
S	George Odum (Knee)	Out

49ers vs Cardinals Betting Prediction: Arizona

This is the 49ers vs Cardinals Betting prediction for Arizona.

At the beginning of week 18, the Arizona Cardinals have a record of 7-9, which places them 15th in our power rankings. Additionally, they have a scoring margin of -0.1. A loss to the Panthers by a score of 36-30 in week 16 and a loss to the Rams by a score of 13-9 in week 17 are the two consecutive losses that they have suffered. Although Arizona was a 6.5-point underdog versus Los Angeles, they were still able to cover the spread despite the city’s defeat.

As the Cardinals do not have any prospects of making the playoffs, they will be looking to close the season on a high note when they play the 49ers at home in week 18. This season, Arizona has a record of 10-6 against the spread, including a record of 7-2 when they are the underdog. Despite having a 46.8-point line, their overall record is 7-8-1, and their games have an average of 44.2 points scored against them.

Our offensive power rankings currently have the Cardinals in the fourteenth spot heading into week 18. They rank 16th in the National Football League in terms of scoring, with an average of 22.1 points per game, and 11th in terms of total offense, with 356.1 yards per game. As a result of Arizona’s reliance on the run game, the team now ranks seventh in terms of running yards per game (143.8) and has 27.2 attempts per game. The percentage of times they convert on third down is 43.4%, which places them seventh among all teams in the league.

Kyler Murray had a loss to the Rams in week 17, during which he threw for 321 yards on 33/48 passing, with one touchdown and two interceptions. There was also one touchdown. They fired him four times. Trey McBride led the club in receptions with 12 and 123 yards, while Michael Carter came in second with 70 yards on the ground after carrying the ball 13 times. However, Arizona was only able to score nine points, all of which came in the second half of the game.

The Cardinals’ defense allowed the Rams to record only 3.1 yards per attempt on 22 rushes, for a total of 68 yards, during their game against the Rams, which they lost 13-9. Additionally, Arizona was able to restrict the Rams to 189 passing yards on 17 completions, resulting in a completion percentage equal to 53.1%. They were unable to register any sacks, and as a result, they suffered a loss of four points in the quarterback hit differential.

The defense of the Cardinals was strong on third downs, and as a result, the Rams were only able to convert forty percent of their third down attempts. In spite of this, the Cardinals’ offense had a difficult time, and the squad as a whole was unable to come out on top.

49ers vs Cardinals Betting: Arizona Injury Report

49ers vs Cardinals Betting Prediction: Our Picks

Next in this 49ers vs Cardinals Betting prediction, we have the picks for this game.

49ers vs Cardinals Betting Prediction: MoneyLine

First, we have the 49ers vs Cardinals Betting prediction on the moneyline.

We have the 49ers ranked 12th in our offensive power rankings as we enter week 18. They have a scoring average of 22.8 points per game, which places them thirteenth in the National Football League, and they have a total yardage average of 372.6 per game, which places them fifth.

The team ranks fourth in passing yards per game, averaging 246 yards, despite the fact that they rank 24th in passing attempts. When it comes to the ground, they rank fourteenth in terms of rushing attempts and eleventh in terms of rushing yards per game, with a total of 126.6. The percentage of third-down conversions that San Francisco achieves places them ninth in the National Football League, while their percentage of red zone conversions places them twenty-third.

Against the Lions in week 17, Brock Purdy passed for 377 yards, three touchdowns, and two interceptions. He also turned the ball over twice. Among the team’s catches, Ricky Pearsall led the way with eight for 141 yards. During the game, San Francisco was successful on five out of eight third downs and scored on each of their five trips into the red zone.

Our offensive power rankings currently have the Cardinals in the fourteenth spot heading into week 18. They rank 15th in the National Football League in terms of points scored per game (22.1) and 11th in terms of total yards gained per game (356.1). To put that into perspective, Arizona’s passing offense ranks 18th in the league with 212.3 yards per game on 31.8 attempts per game, while its rushing attack is seventh in the league with 143.8 yards per game on 27.2 attempts. On third down, the Cardinals have been very successful, converting 43.4% of their attempts, which places them seventh in the National Football League.

During the seventeenth week of the season, Kyler Murray passed for 321 yards (33/48), with one touchdown and two interceptions. His performance in the game against the Rams resulted in four sacks. Trey McBride led the team in receptions with 12 and 123 yards, and Michael Carter led the team in running yards with 70 yards when he carried the ball 13 times. After scoring three points in the fourth quarter and six points in the third quarter, Arizona was unable to score in the first half.

• Free MoneyLine 49ers vs Cardinals Betting Prediction: ARIZONA.

49ers vs Cardinals Betting Prediction: Total

Now, we have the 49ers vs Cardinals Betting prediction on the total.

During the 49ers’ game against the Lions, which they lost by a score of 40-34, their defense had a difficult time getting off the field, which allowed the Lions to convert 64.3% of their third down opportunities. Detroit had an average of 8.4 yards per attempt via the air, while the 49ers allowed them to pass for 287 yards on 26 completions. In addition to that, they surrendered three touchdowns of the passing variety and 152 yards of rushing on 33 tries.

During the game, the defense of San Francisco only managed to record two sacks, and they allowed the quarterbacks of the Lions to complete 76.5% of their interceptions. When the 49ers play their next game, they will be trying to make substantial progress on the defensive side of the ball from their previous performance.

The defense of the Cardinals performed admirably in their loss to the Rams by a score of 13-9. They were able to limit the Rams to only 3.1 yards per attempt on 22 rush offenses. In addition, Arizona only allowed 189 passing yards and 257 total yards, while the Rams were successful in converting forty percent of their third down opportunities. On the other hand, Arizona’s defense had a difficult time generating pressure, as they did not record any sacks and had a -4 disparity in quarterback hits.

It was tough for the Rams to turn the tide of the game in their favor since Arizona’s defense prevented them from reaching the end zone. However, the Rams were unable to get enough pressure on the quarterback. As a result of their offensive struggles, the Cardinals only managed to score nine points throughout the game.

• Free Total 49ers vs Cardinals Betting Prediction: UNDER.

49ers vs Cardinals Betting Prediction: Spread

Next, we have the 49ers vs Cardinals Betting prediction on the spread.

Our NFL power rankings have the 49ers ranked eighth heading into week 18, despite the fact that they have a record of 6-10 and are currently on a losing streak of three games. Even though they were the underdogs, they were unable to cover the 3.5-point spread in their most recent loss, which occurred in week 17 and took place at home against the Lions. When the 49ers scored 74 points in total during that game, they comfortably eclipsed the 50-point line, making it the second game in a row that they have scored more than 50 points.

This season, San Francisco has a record of 5-11 against the spread, with an average scoring margin of -1.5 to their name. Both as favorites and as underdogs, they have a record of 5-8. Taking into account the over/under, they have a record of 9-7, with their games average 47.1 points and the line for their games being 46.5 points.

San Francisco has a record of 0-3 over their most recent three games played during the regular season on the road. In addition to having a record of 2-1 against the over-under, the team’s record against the spread was no better than 0-3.
The San Francisco 49ers have a straight up record of 2-3 in their last five games played away from home, while they have a record of 1-4 against the spread. During this span, the club scored about 19 points per game on average.

When we enter week 18, the Cardinals have a record of 7-9, which places them in the fifteenth spot in our power rankings. Following their victory against the Patriots in week 15, they have now lost two games in a row, the most recent of which was a 13-9 loss to the Rams in week 17. Despite the fact that they were an underdog by 6.5 points, Arizona was able to cover the spread.

While the Cardinals have a scoring margin of -0.1, they have a record of 10-6 against the spread. Their record as underdogs is 7-2, while their record as favorites is 2-4. Despite having a 46.8-point line, their overall record is 7-8-1, and their games have an average of 44.2 points scored against them.

The Cardinals have won all three of their most recent games, resulting in a perfect 2-1 record. Additionally, this involves having a 2-1 over-under mark and a 2-1 overall record.
Over the course of their most recent five home games, Arizona has a record of 3-2 against the bookmakers. All things considered, they finished with a record of 1-4 in these games, averaging 19 points per contest.

• Free Spread 49ers vs Cardinals Betting Prediction: SAN FRANCISCO.

FREE 49ers vs Cardinals Betting Prediction: Our Picks

• Free MoneyLine 49ers vs Cardinals Betting Prediction: ARIZONA.
• Free Total 49ers vs Cardinals Betting Prediction: UNDER.
• Free Spread 49ers vs Cardinals Betting Prediction: SAN FRANCISCO.

 

Read the NFL Betting Frequently Asked Questions. Visit the Betting School and learn how to wager on the moneyline, spread, and total; on your favorite team or an undervalued underdog. Sign up with YouWager.lv now and get in the game with the best welcome bonus, click below: