Detroit Pistons vs Cleveland Cavaliers Prediction, Game 6, NBA Conference Semifinals. LOSE BY 0.5 TWICE? WE REWARD BAD BEATS Claim your bonus and bet this game now

As part of their second-round NBA playoff series, the Cleveland Cavaliers, who are ranked fourth, and the Detroit Pistons, who are ranked first, will compete against each other on Friday, May 15.

Who will reign supreme in the NBA playoff game? A look at these NBA playoffs choices and predictions for the clash between the two teams in the Eastern Conference semifinals below.

With regard to the NBA playoffs, the Cavaliers are a 3.5-point favorite over the Pistons, according to the odds offered by YouWager Sportsbook. There is a moneyline wager of -180 on Cleveland. It is +145 in Detroit. The total number of points that have to be scored in the game is 208.5. 3-2, the Cavaliers are now in the lead in the series against the Pistons.

Detroit Pistons vs Cleveland Cavaliers Prediction – 5-15-2026 – NBA Betting Picks

At this point, the front office of the Cleveland Cavaliers will be a contented unit.Following the blockbuster transaction that resulted in the Cavaliers acquiring James Harden, the team’s goal was to have a successful postseason run. The situation appeared to be a little bit precarious as they advanced to the second round of the playoffs. The squad was competing against the Detroit Pistons, which is the reason behind this. As the games progressed, however, the move that the Cavaliers made to bring in the 36-year-old player began to yield significant benefits for the team.

Upon the conclusion of Game 4, both teams were deadlocked 2-2. In light of this, it was essential for both teams to prevail in Game 5. To the relief of the Cavaliers, Harden made the decision to put on one of his most impressive performances. The former top player for the Los Angeles Clippers dominated the game by scoring 30 points, grabbing eight rebounds, and dishing out six other assists. With such an outstanding effort, Harden becomes the third player since 2010 to produce such stats in a playoff game, joining Kobe Bryant and Shai Gilgeous-Alexander in the ranks of accomplished players.

Having momentum on their side, the Cavaliers will attempt to win Game 6 of the series in order to complete the series. Unfortunately, the Pistons are appearing to be in a somewhat precarious position. Cunningham emerged as the solitary performer for his team as a result of the heated situations that occurred in the middle of the tournament. Cunningham added 39 points after logging in for a total of forty-eight minutes. Regrettably, this was not sufficient for the Pistons to bring home the victory. It is imperative that Detroit pulls itself together as Game 6 draws near; else, Cleveland will be the team to beat in the championship game.

Our Detroit Pistons vs Cleveland Cavaliers Pick: CAVALIERS

Is it possible for the visitors, who have lost their hold on the series, to gradually regain their footing? In Game 6 of the Eastern Conference playoffs in the National Basketball Association, the Cleveland Cavaliers will play host to the Detroit Pistons. After suffering defeat in the first two games of the series, the Cavaliers have completed a remarkable turnaround and are now in the lead in the series, 3-2. To make their first appearance in the conference finals since 2018, Atkinson’s team is only one victory away from achieving that goal. With Cleveland still undefeated at home in this postseason, their chances of winning appear to be favorable. The question that needs to be answered is whether or not the Michigan team still has enough of a chance to compel a decisive Game 7 to be played in Detroit. In order to provide a prediction that is based on solid evidence, let’s analyze this matchup.

Detroit Pistons vs Cleveland Cavaliers Prediction – FAQ’s

Q: For the Cavaliers and the Pistons, what are the head-to-head statistics that compare the two teams?
A: Cavaliers 110 Pistons 135

Q: Will James Harden show up for the game against the Pistons?
A: James Harden is anticipated to participate in the game against the Pistons.

Q: Do you know where the Cavaliers and the Pistons will be playing their game?
A: Rocket Arena, Cleveland

Q: Who emerged victorious in the most recent matchup between the Cavaliers and the Pistons?
A: Cavaliers 117, Pistons 113.

Detroit Pistons vs Cleveland Cavaliers Prediction – Betting Trends

In four of Detroit’s most recent six games, the total has been taken over.

The over/under record for Detroit’s last seven games versus Cleveland is 2-5.

In its last 20 games versus Cleveland, Detroit has a winning percentage of 5-15.

In its previous six games played away from home, Detroit has a record of 1-5 against the spread.

Detroit has a losing record of 1-12 against the spread in its last 13 games while playing Cleveland away from home.

Over the course of its most recent 19 games versus teams from the Central Division, Detroit has a winning percentage of 14-5.

In its previous 13 games played in May, Detroit has a record of 4-9 against the spread.

Four out of the last six games that Detroit has played on a Friday have resulted in the total going UNDER.

Over the past six games, Cleveland has a record of 4-2 against the spread.

For Cleveland’s last eight games, the total has been over in six of those games.

In its last 18 games, Cleveland has a winning percentage of 12-6.

Over the course of Cleveland’s last 20 games versus Detroit, the total has been under in 14 of those games.

At home, Cleveland has a perfect record of 10-0 in its last ten games.

When playing at home versus Detroit, Cleveland has a winning record of 12-1 as a team in its last 13 games.

Nine out of Cleveland’s previous thirteen games against opponents from the Eastern Conference conference have resulted in the total going over the point spread.

Over the course of its last 15 games against opponents from the Central Division, Cleveland has a record of 5-10 against the spread.

Ten of Cleveland’s previous fourteen games played in the month of May have resulted in the total going over.

After 18 games played on Fridays, Cleveland has a record of 6-12 against the spread.

Detroit Pistons vs Cleveland Cavaliers Prediction – Head to Head

In the 69 instances that these two teams have competed against one another, Cleveland has emerged victorious 44 times, giving them a considerable advantage. Also, the Cavaliers prevailed in their most recent matchup, which took place on May 14, when they defeated their competitors by a score of 117-113 in overtime.

Date | Team | Opp | Close | Result | ATS/OU
May 13, 2026 | Cavaliers | @Pistons | +4 / 210.5 | Won 117-113 | Won / Over
May 11, 2026 | Cavaliers | Pistons | -3.5 / 213.5 | Won 112-103 | Won / Over
May 9, 2026 | Cavaliers | Pistons | -5 / 211.5 | Won 116-109 | Won / Over
May 7, 2026 | Cavaliers | @Pistons | +3.5 / 214.5 | Lost 97-107 | Lost / Under
May 5, 2026 | Cavaliers | @Pistons | +3.5 / 217.5 | Lost 101-111 | Lost / Under
Mar 3, 2026 | Cavaliers | Pistons | +2.5 / 228 | Won 113-109 | Won / Under
Feb 27, 2026 | Cavaliers | @Pistons | +8.5 / 227.5 | Lost 119-122 | Won / Over
Jan 4, 2026 | Cavaliers | Pistons | -3.5 / 239.5 | Lost 110-114 | Lost / Under
Oct 27, 2025 | Cavaliers | @Pistons | -2 / 231.5 | Won 116-95 | Won / Under
Oct 14, 2025 | Cavaliers | Pistons | -8 / 235.5 | Won 118-100 | Won / Under

Detroit Pistons vs Cleveland Cavaliers Prediction – Pistons Last 10 Games

Date | Opponent | Score | Spread | Total | Moneyline

5/13/26

CLE

L 117-113

L-3.5

O212.5

L-162

5/11/26

@CLE

L 112-103

L+3.5

O212.5

L+136

5/09/26

@CLE

L 116-109

L+3.5

O211.5

L+132

5/07/26

CLE

W 107-97

W-3.5

U215.5

W-164

5/05/26

CLE

W 111-101

W-3.5

U214.5

W-155

5/03/26

ORL

W 116-94

W-8.5

O203.5

W-380

5/01/26

@ORL

W 93-79

W-3.0

U211.5

W-160

4/29/26

ORL

W 116-109

L-9.5

O209.5

W-163

4/27/26

@ORL

L 94-88

L-3.5

U212.5

L+900

4/25/26

@ORL

L 113-105

L-2.5

O217.5

L+456

Detroit Pistons vs Cleveland Cavaliers Prediction – Cavs Last 10 Games

Date | Opponent | Score | Spread | Total | Moneyline

5/13/26

@DET

W 117-113

W+3.5

O212.5

W+136

5/11/26

DET

W 112-103

W-3.5

O212.5

W-162

5/09/26

DET

W 116-109

W-3.5

O211.5

W-156

5/07/26

@DET

L 107-97

L+3.5

U215.5

L+138

5/05/26

@DET

L 111-101

L+3.5

U214.5

L+130

5/03/26

TOR

W 114-102

W-7.5

O211.5

W-295

5/01/26

@TOR

L 112-110

L-3.5

O219.5

L-166

4/29/26

TOR

W 125-120

L-6.5

O217.5

W-1150

4/26/26

@TOR

L 93-89

L-2.5

U220.5

L-270

4/23/26

@TOR

L 126-104

L-3.5

O218.5

L-233

Detroit Pistons vs Cleveland Cavaliers Prediction – Pistons Offense

Overall

DET Offense | Off. Rank | Stat | Def. Rank | CLE Defense
117.56 | 9 | Points Scored | 16 | 115.40
48.06 | 6 | Field Goal % | 9 | 46.03
35.21 | 19 | Three Point % | 28 | 37.24
75.63 | 27 | Free Throw % | 23 | 79.64
45.67 | 7 | Total Rebounds | 14 | 43.84

Scoring

DET Offense | Off. Rank | Stat | Def. Rank | CLE Defense
117.56 | 9 | Points Scored | 16 | 115.40
29.73 | 12 | First Quarter | 6 | 28.07
30.85 | 1 | Second Quarter | 25 | 29.91
28.65 | 21 | Third Quarter | 17 | 29.12
28.07 | 11 | Fourth Quarter | 18 | 27.93

Shooting

DET Offense | Off. Rank | Stat | Def. Rank | CLE Defense
48.06 | 6 | Field Goal % | 9 | 46.03
75.63 | 27 | Free Throw % | 23 | 79.64
35.21 | 19 | Three Point % | 28 | 37.24
31.71 | 27 | Three’s Attempts | 20 | 37.97
11.16 | 27 | Three’s Made | 24 | 14.14

Rebounds

DET Offense | Off. Rank | Stat | Def. Rank | CLE Defense
13.05 | 5 | Offensive | 19 | 11.72
32.62 | 13 | Defensive | 12 | 32.12
45.67 | 7 | Total Rebounds | 14 | 43.84

Other

DET Offense | Off. Rank | Stat | Def. Rank | CLE Defense
26.85 | 11 | Assists | 13 | 26.78
22.31 | 1 | Fouls | 15 | 20.17
14.35 | 22 | Turnovers | 7 | 14.97
10.64 | 1 | Steals | 20 | 8.79

Detroit Pistons vs Cleveland Cavaliers Prediction – Cavs Offense

Overall

DET Defense | Def. Rank | Stat | Off. Rank | CLE Offense
109.33 | 3 | Points Scored | 3 | 119.69
44.16 | 2 | Field Goal % | 9 | 47.75
34.67 | 5 | Three Point % | 15 | 35.87
79.35 | 22 | Free Throw % | 17 | 78.32
41.18 | 4 | Total Rebounds | 13 | 44.69

Scoring

DET Defense | Def. Rank | Stat | Off. Rank | CLE Offense
109.33 | 3 | Points Scored | 3 | 119.69
28.27 | 9 | First Quarter | 11 | 29.76
27.02 | 5 | Second Quarter | 19 | 28.48
27.29 | 4 | Third Quarter | 1 | 31.22
26.49 | 7 | Fourth Quarter | 2 | 30.05

Shooting

DET Defense | Def. Rank | Stat | Off. Rank | CLE Offense
44.16 | 2 | Field Goal % | 9 | 47.75
79.35 | 22 | Free Throw % | 17 | 78.32
34.67 | 5 | Three Point % | 15 | 35.87
36.35 | 12 | Three’s Attempts | 5 | 40.57
12.60 | 8 | Three’s Made | 7 | 14.55

Rebounds

DET Defense | Def. Rank | Stat | Off. Rank | CLE Offense
11.38 | 14 | Offensive | 10 | 12.10
29.80 | 3 | Defensive | 14 | 32.59
41.18 | 4 | Total Rebounds | 13 | 44.69

Other

DET Defense | Def. Rank | Stat | Off. Rank | CLE Offense
23.05 | 1 | Assists | 8 | 28.50
21.78 | 29 | Fouls | 16 | 19.93
16.55 | 1 | Turnovers | 12 | 13.78
9.05 | 26 | Steals | 8 | 9.02

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Detroit Pistons vs Cleveland Cavaliers Prediction and Pick, 5-15-2026, by YouWager.lv.