Cardinals vs Yankees MLB Prediction: Why Are the New York Yankees Heavy Favorites at Home? (Monday, August 3, 2026)

Why are the New York Yankees favored over the St. Louis Cardinals on Monday, August 3, 2026?

The New York Yankees are favored because they own one of the best pitching staffs in Major League Baseball, have a strong home-field advantage at Yankee Stadium, and will send Cam Schlittler to the mound. While the St. Louis Cardinals have been solid defensively and possess an experienced starter in Dustin May, New York’s superior pitching, deeper lineup, and overall record make the Yankees the deserved favorites.

This interleague matchup features two clubs heading in different directions. The Yankees enter the game at 62-48 and remain in postseason contention behind elite pitching, while the Cardinals sit at 54-56 and are looking to climb back above .500. Although St. Louis has enough talent to compete, New York holds advantages in both starting pitching and overall team performance.

Table of Contents

Why are the Yankees favored?

Can the Cardinals pull off the upset?

Starting pitcher matchup

Offensive comparison

Bullpen and defensive analysis

Best betting value

Prediction

FAQ

Why are the Yankees favored in this matchup?

Several factors work in New York’s favor entering Monday night’s game.

Elite pitching staff ranked among the best in MLB.

Home-field advantage at Yankee Stadium.

Cam Schlittler owns outstanding career numbers.

The Yankees have allowed significantly fewer runs than St. Louis this season.

New York has one of baseball’s strongest defensive efficiency ratings.

Their combination of quality pitching and reliable run prevention has helped the Yankees build one of the American League’s better records.

Can the Cardinals win as underdogs?

Yes, but they’ll likely need a strong performance from Dustin May.

St. Louis has played respectable baseball on the defensive side, ranking among the league leaders in fielding percentage while also limiting home runs better than many clubs. If May can neutralize New York’s power hitters early, the Cardinals have enough pitching depth to stay within striking distance.

However, their offense has been inconsistent, averaging just 4.3 runs per game compared to New York’s more productive lineup.

How do Dustin May and Cam Schlittler compare?

Cam Schlittler (Yankees)

Schlittler has quickly developed into one of the more effective young pitchers in baseball.

Career Stats

Stat | Cam Schlittler
Record | 14-9
ERA | 2.37
WHIP | 1.018
Strikeouts | 249

His ability to limit baserunners while generating strikeouts gives New York a significant edge in this matchup.

Dustin May (Cardinals)

May brings valuable experience and quality stuff to the mound.

Career Stats

Stat | Dustin May
Record | 24-27
ERA | 3.99
WHIP | 1.222
Strikeouts | 403

May has proven capable of keeping offenses under control, but he’ll face one of the tougher assignments against a powerful Yankees lineup.

Which offense has the advantage?

New York Yankees

The Yankees have been the more productive offense overall.

4.62 runs per game

155 home runs

165 doubles

405 walks

.413 slugging percentage

Their patience at the plate and power throughout the lineup make them dangerous in every inning.

St. Louis Cardinals

The Cardinals have struggled to generate consistent offense.

4.3 runs per game

.238 batting average

.314 on-base percentage

113 home runs

.377 slugging percentage

St. Louis will likely need timely hitting with runners in scoring position to keep pace.

Who has the edge in the bullpen and defense?

New York owns the advantage on the mound, while St. Louis shines defensively.

Yankees

3.28 team ERA

Fourth-fewest runs allowed in MLB

Excellent bullpen in high-leverage situations

Top-10 defensive efficiency

Cardinals

Sixth-best fielding percentage

69 bullpen holds

Solid relief depth

Better at avoiding defensive mistakes

While St. Louis fields the ball exceptionally well, New York’s overall pitching depth gives the Yankees the late-game edge.

What is the best betting value?

The Yankees deserve to be favored based on their dominant pitching staff and home-field advantage.

Cam Schlittler has been outstanding throughout his career, and New York’s offense provides more consistent run support than the Cardinals have received this season.

Although -150 isn’t a bargain price, the Yankees appear to be the stronger team entering this matchup.

Prediction

St. Louis has enough pitching and defense to stay competitive early, but New York’s combination of elite pitching, deeper lineup, and home-field advantage should prove too much over nine innings.

Best Bet: New York Yankees -150

FAQ

Who is favored in Cardinals vs Yankees on August 3, 2026?

The New York Yankees are favored at -150, while the St. Louis Cardinals are +125 underdogs.

Who are the projected starting pitchers?

Dustin May is expected to start for St. Louis, while Cam Schlittler is scheduled to pitch for New York.

Why are the Yankees favorites?

New York owns one of MLB’s best pitching staffs, has home-field advantage, and sends Cam Schlittler to the mound with an outstanding career ERA and WHIP.

Can the Cardinals cover as underdogs?

Yes. St. Louis has one of the league’s best fielding percentages and an experienced starter in Dustin May, giving them a chance to keep the game close.

What is the recommended pick?

The recommended wager is New York Yankees -150, as the Yankees have clear advantages in pitching, overall roster depth, and home-field advantage.

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Cardinals vs Yankees MLB Prediction and Pick, 8-3-2026. MLB Betting Picks, by YouWagert.lv