Oregon vs Iowa Prediction and Pick, Week 11. Place a bet on this CFB football game with the best odds.

Oregon vs Iowa Prediction: Trends

In four of Oregon’s most recent six games, the total has been under the OVER.

In its last 20 games, Oregon has a state record of 18-2.

On the road, Oregon has a perfect record of 10-0 in its last ten games.

Over the course of its last ten games versus opponents from the Big Ten league, Oregon has a winning record of 8-2.

Five of Oregon’s most recent five games against opponents from the West Division division have resulted in the total going UNDER rather than over.

After six games played in November, Oregon has a record of 4-2 against the spread.

In its last seven games played in week 11, Oregon has a record of 2-5 against the spread.

Over the past six games, Iowa has a record of 5-1 against the spread.

Four of Iowa’s most recent six games have resulted in the total going over.

In its last six games, Iowa has a winning record of 5-1 against the spread.

In Iowa’s previous ten games played at home, the Hawkeyes have a winning record of 9-1.

In its last seven games versus a team from the Big Ten conference, Iowa has a winning record of 6-1 as a team.

Nine of Iowa’s last twelve games played in November have resulted in the total going UNDER as a wager.

In four of Iowa’s most recent five games played in week 11, the total has been counted as UNDER.

After five games played on Saturdays, Iowa has a record of 4-1 against the spread.

Iowa has a record of 1-4-1 against the spread in their previous six games when they were the underdog.

Oregon vs Iowa Prediction

Now we have the Oregon vs Iowa Prediction for both teams.

The Week 11 matchup between the Oregon Ducks and the Iowa Hawkeyes promises to be one of the most fascinating cross-conference showdowns of the season. Oregon comes in with one of the most efficient and explosive offenses in college football, balanced by a top-tier defense that thrives on shutting down both the pass and the run. Meanwhile, Iowa continues to play its signature brand of disciplined, physical football—leaning on a stifling defense and a run-first offense that grinds down opponents. The Ducks are 18-2 over their last 20 games and haven’t lost a road contest in their last ten trips away from Eugene, while Iowa boasts an incredible 9-1 record in its last ten home games. Both programs are known for their physicality and defensive grit, which makes this a classic strength-on-strength battle. With Oregon’s top-10 rushing attack set to face Iowa’s elite run defense, and the Hawkeyes’ ball-control offense going up against one of the most complete defensive units in the country, this matchup could very well hinge on turnovers, field position, and special teams execution rather than offensive fireworks.

For Oregon, the formula remains the same: strike early, dictate tempo, and overwhelm opponents with offensive balance. The Ducks are averaging over 41 points per game, ranking fifth nationally, and they’ve done so behind a rushing attack that’s among the nation’s best—237 yards per game at a staggering 6.28 yards per carry. Even with some inconsistency in passing yardage, Oregon’s efficiency per play (7.37 yards) shows just how lethal they are at generating big gains. The offensive line has done a solid job keeping the quarterback upright, and the Ducks’ versatility allows them to stay dangerous regardless of defensive schemes. Defensively, Oregon has been phenomenal—allowing just 13.5 points per game—and that balance makes them so tough to beat. They’ve proven capable of controlling both the air and ground, ranking top 10 in multiple key defensive categories. The Ducks’ road dominance, including a 10-0 stretch away from home, underscores how well-prepared this team is in high-pressure environments. They’re disciplined, explosive, and opportunistic, a combination that has made them one of the toughest teams in the nation to slow down.

Iowa, on the other hand, thrives on grit and execution rather than flash. The Hawkeyes have been on a tear lately, covering the spread in five of their last six and winning big against teams like Penn State and Wisconsin. Their defense continues to be one of the most fundamentally sound in the nation—allowing just 13.13 points per game—and the Hawkeyes’ ability to force teams into uncomfortable situations is what keeps them in every contest. Offensively, Iowa has leaned on its run game, averaging 185.25 rushing yards per game, which helps them control the clock and keep their defense fresh. While their passing game ranks near the bottom nationally, they make up for it with efficient drives, strong field position, and a special teams unit that consistently wins the hidden yardage battle. Kinnick Stadium has been a fortress for Iowa, and their physical brand of football is tailor-made to frustrate high-scoring teams like Oregon. If the Hawkeyes can limit turnovers and keep Oregon’s explosive plays in check, they could very well turn this into a fourth-quarter slugfest.

Our CFB Week 11 Pick: OREGON

Oregon vs Iowa Prediction: Head to Head

N/A

Oregon vs Iowa Prediction: Oregon Last 10 Games

Date | Opponent | Score | Spread | Total | Moneyline

10/25/25

WIS

W 21-7

L-29.5

U44.5

W-20000

10/18/25

@RUT

W 56-10

W-16.5

O57.5

W-710

10/11/25

IU

L 30-20

L-14.0

U55.5

L-690

9/27/25

@PSU

W 30-24

W+3.5

O52.5

W+128

9/20/25

ORS

W 41-7

W-27.5

U55.5

W-30000

9/13/25

@NW

W 34-14

L-30.5

U52.5

W-10000

9/06/25

OKS

W 69-3

W-23.5

O58.5

W-7000

8/30/25

MOS

W 59-13

W-27.5

O54.5

W-7000

1/01/25

OSU

L 41-21

L+2.5

O53.5

L+108

12/07/24

PSU

W 45-37

W-3.0

O51.5

W-148

Oregon vs Iowa Prediction: Iowa Last 10 Games

Date | Opponent | Score | Spread | Total | Moneyline

10/25/25

MIN

W 41-3

W-8.5

O39.5

W-320

10/18/25

PSU

W 25-24

W+10.5

O46.5

W+315

10/11/25

@WIS

W 37-0

W-1.5

U38.5

W-125

9/27/25

IU

L 20-15

L+2.5

U48.5

L+104

9/19/25

@RUT

W 38-28

W-1.5

O42.5

W-114

9/13/25

UMASS

W 47-7

W-34.5

O44.5

W-10000

9/06/25

@ISU

L 16-13

L-1.5

U45.5

L-114

8/30/25

ALB

W 34-7

L-32.5

U45.5

W-12405

12/30/24

@MIZ

L 27-24

L+2.5

O43.5

L+105

11/29/24

NEB

W 13-10

L-4.0

U37.5

W-184

Oregon vs Iowa Prediction: Oregon Offense

Overall

OREG Offense | Off. Rank | Stat | Def. Rank | IOWA Defense
41.25 | 5 | Points Scored | 4 | 13.13
246.88 | 52 | Passing Yards | 5 | 151.00
237.00 | 9 | Rushing Yards | 10 | 83.88
30:51 | 47 | Time on Field | 37 | 28:46
65.63 | 85 | Number of Plays | 9 | 58.63
7.37 | 3 | Yards Per Play | 4 | 4.01

Scoring

OREG Offense | Off. Rank | Stat | Def. Rank | IOWA Defense
41.25 | 5 | Points Scored | 4 | 13.13
9.00 | 17 | First Quarter | 44 | 4.25
13.38 | 5 | Second Quarter | 16 | 4.75
12.13 | 3 | Third Quarter | 1 | 1.25
5.13 | 104 | Fourth Quarter | 5 | 2.88

Passing

OREG Offense | Off. Rank | Stat | Def. Rank | IOWA Defense
246.88 | 52 | Passing Yards | 5 | 151.00
27.88 | 100 | Pass Attempts | 20 | 26.88
19.75 | 59 | Pass Completions | 9 | 15.00
1.38 | 36 | Sacks | 56 | 2.13
9.25 | 99 | Sack Yards | 81 | 14.25
12.50 | 43 | Yards Per Pass | 13 | 10.07

Rushing

OREG Offense | Off. Rank | Stat | Def. Rank | IOWA Defense
237.00 | 9 | Rushing Yards | 10 | 83.88
37.75 | 48 | Rush Attempts | 17 | 31.75
6.28 | 2 | Yards Per Rush | 8 | 2.64

Turn Overs

OREG Offense | Off. Rank | Stat | Def. Rank | IOWA Defense
0.50 | 27 | Interceptions | 24 | 1.13
0.63 | 16 | Fumbles | 56 | 1.13
0.25 | 24 | Fumbles Lost | 111 | 0.25
0.75 | 11 | Total Turnovers | 52 | 1.38
4.75 | 21 | Penalties | 136 | 3.25
40.88 | 21 | Penalty Yards | 136 | 25.88

Drives & Special Teams

OREG Offense | Off. Rank | Stat | Def. Rank | IOWA Defense
30:51 | 47 | Time on Field | 37 | 28:46
65.63 | 85 | Number of Plays | 9 | 58.63
7.37 | 3 | Yards Per Play | 4 | 4.01
2.13 | 8 | Punts | 22 | 5.25
42.19 | 88 | Punt Average | 56 | 42.19
50.00 | 88 | Return Yards | 10 | 28.25

Oregon vs Iowa Prediction: Iowa Offense

Overall

OREG Defense | Def. Rank | Stat | Off. Rank | IOWA Offense
13.50 | 6 | Points Scored | 53 | 31.25
124.63 | 1 | Passing Yards | 132 | 132.63
114.75 | 31 | Rushing Yards | 38 | 185.25
29:08 | 48 | Time on Field | 34 | 31:13
59.13 | 10 | Number of Plays | 123 | 61.75
4.05 | 5 | Yards Per Play | 104 | 5.15

Scoring

OREG Defense | Def. Rank | Stat | Off. Rank | IOWA Offense
13.50 | 6 | Points Scored | 53 | 31.25
2.50 | 12 | First Quarter | 9 | 9.63
1.50 | 1 | Second Quarter | 56 | 9.38
1.25 | 2 | Third Quarter | 103 | 4.50
7.38 | 96 | Fourth Quarter | 49 | 7.75

Passing

OREG Defense | Def. Rank | Stat | Off. Rank | IOWA Offense
124.63 | 1 | Passing Yards | 132 | 132.63
24.75 | 3 | Pass Attempts | 127 | 23.50
12.13 | 1 | Pass Completions | 119 | 15.00
1.75 | 93 | Sacks | 33 | 1.38
8.63 | 20 | Sack Yards | 112 | 7.25
10.28 | 16 | Yards Per Pass | 135 | 8.84

Rushing

OREG Defense | Def. Rank | Stat | Off. Rank | IOWA Offense
114.75 | 31 | Rushing Yards | 38 | 185.25
34.38 | 62 | Rush Attempts | 42 | 38.25
3.34 | 23 | Yards Per Rush | 39 | 4.84

Turn Overs

OREG Defense | Def. Rank | Stat | Off. Rank | IOWA Offense
1.13 | 27 | Interceptions | 45 | 0.63
1.25 | 44 | Fumbles | 14 | 0.63
0.25 | 121 | Fumbles Lost | 10 | 0.13
1.38 | 56 | Total Turnovers | 10 | 0.75
5.38 | 100 | Penalties | 1 | 2.38
35.38 | 128 | Penalty Yards | 1 | 22.88

Drives & Special Teams

OREG Defense | Def. Rank | Stat | Off. Rank | IOWA Offense
29:08 | 48 | Time on Field | 34 | 31:13
59.13 | 10 | Number of Plays | 123 | 61.75
4.05 | 5 | Yards Per Play | 104 | 5.15
6.00 | 10 | Punts | 37 | 3.25
44.20 | 108 | Punt Average | 104 | 41.48
29.50 | 13 | Return Yards | 1 | 113.00

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Oregon vs Iowa Prediction and Pick, Week 11, by YouWager.lv.