Indiana vs Penn State Prediction and Pick, Week 11. Place a bet on this CFB football game with the best odds.

Indiana vs Penn State Prediction: Trends

Over the past eight games, Indiana has a record of 6-2 against the spread.

It has been six out of Indiana’s last eight games that the total has gone over.

Indiana has a perfect record SU in its previous nine games.

After six games against Penn State, Indiana has a record of 4-2 against the spread.

In its last ten games versus Penn State, Indiana has a record of 1-9 all-time.

In twelve of Indiana’s most recent fifteen games played away from home, the total has been above.

When playing Penn State away from home, Indiana has a losing record of 0-10 by the single-score in its last ten games.

Indiana’s last seven games against opponents from the Big Ten conference have resulted in a perfect seven-game winning streak for the Hoosiers.

Nine out of Indiana’s last eleven games against opponents from the East Division division have resulted in the total going over the point spread.

After nine games played in November, Indiana has a record of 6-3 against the spread.

Over the past nine games, Penn State has a record of 1-8 against the spread.

Five of Penn State’s most recent six games have resulted in the total going over.

In its last five games, Penn State has a losing record of 0-5 against the spread.

During Penn State’s most recent six meetings versus Indiana, the total has been above in five of those games.

In its last five games played at home, Penn State has a record of 0-5 against the spread.

As a result of playing at home versus Indiana, Penn State has a perfect record of 10-0 in its previous ten games.

In their last six games against opposing teams from the Big Ten conference, Penn State has a losing record of 0-6 on the road.

When Penn State has played an opponent from the East Division, the total has been UNDER in four of the last six games that Penn State has performed against.

Four out of the five games that Penn State has played in November have resulted in the total going over.

After six games played in week 11, Penn State has a record of 2-4 against the spread.

Indiana vs Penn State Prediction

Now we have the Indiana vs Penn State Prediction for both teams.

The Week 11 matchup between Indiana and Penn State offers a fascinating clash between a surging Hoosiers squad and a Penn State team trying to salvage pride amid a rough stretch. Indiana enters this contest as one of the hottest teams in the Big Ten, having won nine straight games and covering the spread in six of their last eight. The Hoosiers have also seen the total go over in six of those contests, largely thanks to their explosive offense that ranks among the best in college football. On the other hand, Penn State’s recent form has been a stark contrast. The Nittany Lions are just 1-8 against the spread in their last nine games and have failed to cover in five straight at home. Despite owning a perfect 10-0 record at home against Indiana in their last ten meetings, this Penn State team appears vulnerable on both sides of the ball, struggling to maintain consistency against Big Ten opponents. This matchup will test whether Indiana’s balanced attack and dominant defensive front can finally overcome Penn State’s historical edge in Beaver Stadium.

Indiana’s success this season has been nothing short of remarkable. The Hoosiers rank first in the nation in points scored at 46.4 per game and are top-10 in both rushing yards and yards per play. Quarterback play has been efficient, with the offense averaging over 259 passing yards per game while maintaining excellent balance on the ground, rushing for nearly 246 yards per contest. That kind of dual-threat capability has made Indiana difficult to contain, and their offensive line has been particularly impressive—allowing less than one sack per game on average. What makes Indiana even more dangerous is their ability to dominate time of possession, holding the ball for over 34 minutes per game while wearing down defenses. On the defensive side, the Hoosiers are just as dominant, ranking third nationally in points allowed (10.8) and top five in rushing defense, giving up only 80 yards per game. Their ability to pressure quarterbacks and force quick decisions could spell trouble for a Penn State offense that’s struggled to find rhythm. Indiana’s discipline, balance, and consistency on both sides of the ball make them one of the most complete teams in the country heading into Week 11.

Penn State, meanwhile, is in freefall after a promising start to the season. The Nittany Lions have dropped several close games, losing five straight against the spread and three of their last four outright. Their offense has been inconsistent, ranking just 69th in rushing and 114th in passing—a troubling sign for a team once known for explosive playmaking. Despite scoring 31.5 points per game, Penn State has struggled to move the ball efficiently, averaging just 5.3 yards per play. Defensively, the Nittany Lions have been solid in spots but have shown cracks against high-powered offenses, particularly against the run, where they rank 90th in the nation. Home-field advantage hasn’t meant much lately either, with Penn State failing to cover in its last five at Beaver Stadium. The pressure will be on their defense to slow down an Indiana attack that can score in bunches. Unless Penn State can force turnovers and control tempo early, this game could get out of hand quickly.

Our CFB Week 11 Pick: INDIANA

Indiana vs Penn State Prediction: Head to Head

Date | Opponent | Score | Spread | Total | Moneyline

10/28/23

@PSU

PSU 33-24

PSU-27.5

O47.5

PSU-4000

11/05/22

@IU

PSU 45-14

IU+13.0

O54.5

IU+400

10/02/21

@PSU

PSU 24-0

PSU-12.5

U53.5

PSU-500

10/24/20

@IU

IU 36-35

IU+6.5

O61.5

IU+180

11/16/19

@PSU

PSU 34-27

PSU-14.5

O54.5

PSU-630

10/20/18

@IU

PSU 33-28

NL

NL

NL

9/30/17

@PSU

PSU 45-14

NL

NL

NL

11/12/16

@IU

PSU 45-31

NL

NL

NL

10/10/15

@PSU

PSU 29-7

NL

NL

NL

Indiana vs Penn State Prediction: Indiana Last 10 Games

Date | Opponent | Score | Spread | Total | Moneyline

11/01/25

@MAR

W 55-10

W-16.5

O51.5

W-2800

10/25/25

UCLA

W 56-6

W-21.5

O54.5

W-2300

10/18/25

MSU

W 38-13

W-24.5

O50.5

W-4000

10/11/25

@ORE

W 30-20

W+14.0

U55.5

W+480

9/27/25

@IOW

W 20-15

W-2.5

U48.5

W-125

9/20/25

ILL

W 63-10

W-3.0

O54.5

W-192

9/12/25

INDS

W 73-0

W-41.5

O57.5

W-3500

9/06/25

KENN

W 56-9

W-33.5

O50.5

W-20000

8/30/25

ODU

W 27-14

L-23.5

U53

W-2500

12/20/24

@ND

L 27-17

L+8.5

U51.5

L+245

Indiana vs Penn State Prediction: Penn State Last 10 Games

Date | Opponent | Score | Spread | Total | Moneyline

11/01/25

@OSU

L 38-14

L+4.5

O50.5

L+132

10/18/25

@IOW

L 25-24

L-10.5

O46.5

L-410

10/11/25

NW

L 22-21

L-20.5

U48.5

L-1700

10/04/25

@UCLA

L 42-37

L-27.5

O50.5

L-4500

9/27/25

ORE

L 30-24

L-3.5

O52.5

L-154

9/13/25

VIL

W 52-6

L-48.5

O55.5

WNL

9/06/25

FIU

W 34-0

L-42.5

U56.5

W-20000

8/30/25

NEV

W 46-11

L-43.5

U59.5

W-10000

1/09/25

ND

L 27-24

L+1.5

O47

LEVEN

12/31/24

@BOISE

W 31-14

W-10.0

U59.5

W-400

Indiana vs Penn State Prediction: Indiana Offense

Overall

INDY Offense | Off. Rank | Stat | Def. Rank | PSU Defense
46.44 | 1 | Points Scored | 41 | 21.75
259.22 | 33 | Passing Yards | 14 | 166.38
245.67 | 6 | Rushing Yards | 90 | 159.38
34:43 | 3 | Time on Field | 117 | 31:46
70.22 | 31 | Number of Plays | 37 | 64.25
7.19 | 7 | Yards Per Play | 34 | 5.07

Scoring

INDY Offense | Off. Rank | Stat | Def. Rank | PSU Defense
46.44 | 1 | Points Scored | 41 | 21.75
11.22 | 7 | First Quarter | 18 | 2.88
12.89 | 6 | Second Quarter | 48 | 6.25
13.56 | 1 | Third Quarter | 45 | 4.25
8.78 | 29 | Fourth Quarter | 77 | 6.75

Passing

INDY Offense | Off. Rank | Stat | Def. Rank | PSU Defense
259.22 | 33 | Passing Yards | 14 | 166.38
27.44 | 104 | Pass Attempts | 8 | 26.13
19.78 | 58 | Pass Completions | 29 | 16.88
0.78 | 9 | Sacks | 107 | 1.63
5.22 | 125 | Sack Yards | 34 | 10.50
13.11 | 22 | Yards Per Pass | 8 | 9.86

Rushing

INDY Offense | Off. Rank | Stat | Def. Rank | PSU Defense
245.67 | 6 | Rushing Yards | 90 | 159.38
42.78 | 16 | Rush Attempts | 100 | 38.13
5.74 | 10 | Yards Per Rush | 78 | 4.18

Turn Overs

INDY Offense | Off. Rank | Stat | Def. Rank | PSU Defense
0.56 | 34 | Interceptions | 88 | 0.63
0.56 | 10 | Fumbles | 81 | 1.00
0.11 | 6 | Fumbles Lost | 47 | 0.63
0.67 | 6 | Total Turnovers | 70 | 1.25
4.00 | 8 | Penalties | 135 | 3.38
30.56 | 5 | Penalty Yards | 135 | 26.50

Drives & Special Teams

INDY Offense | Off. Rank | Stat | Def. Rank | PSU Defense
34:43 | 3 | Time on Field | 117 | 31:46
70.22 | 31 | Number of Plays | 37 | 64.25
7.19 | 7 | Yards Per Play | 34 | 5.07
2.00 | 4 | Punts | 115 | 3.50
42.68 | 77 | Punt Average | 3 | 37.43
64.22 | 55 | Return Yards | 47 | 40.50

Indiana vs Penn State Prediction: Penn State Offense

Overall

INDY Defense | Def. Rank | Stat | Off. Rank | PSU Offense
10.78 | 3 | Points Scored | 49 | 31.50
168.33 | 18 | Passing Yards | 114 | 180.38
80.00 | 4 | Rushing Yards | 69 | 155.25
25:15 | 3 | Time on Field | 116 | 28:13
54.67 | 1 | Number of Plays | 113 | 63.25
4.54 | 14 | Yards Per Play | 98 | 5.31

Scoring

INDY Defense | Def. Rank | Stat | Off. Rank | PSU Offense
10.78 | 3 | Points Scored | 49 | 31.50
3.33 | 30 | First Quarter | 103 | 4.75
3.22 | 6 | Second Quarter | 63 | 9.00
1.78 | 7 | Third Quarter | 60 | 6.63
2.44 | 3 | Fourth Quarter | 8 | 10.25

Passing

INDY Defense | Def. Rank | Stat | Off. Rank | PSU Offense
168.33 | 18 | Passing Yards | 114 | 180.38
28.78 | 41 | Pass Attempts | 94 | 28.38
17.44 | 39 | Pass Completions | 91 | 18.13
3.22 | 7 | Sacks | 37 | 1.38
20.67 | 123 | Sack Yards | 95 | 9.50
9.65 | 4 | Yards Per Pass | 126 | 9.95

Rushing

INDY Defense | Def. Rank | Stat | Off. Rank | PSU Offense
80.00 | 4 | Rushing Yards | 69 | 155.25
25.89 | 1 | Rush Attempts | 79 | 34.88
3.09 | 18 | Yards Per Rush | 57 | 4.45

Turn Overs

INDY Defense | Def. Rank | Stat | Off. Rank | PSU Offense
1.44 | 9 | Interceptions | 78 | 0.75
0.78 | 104 | Fumbles | 59 | 1.00
0.56 | 56 | Fumbles Lost | 25 | 0.25
2.00 | 13 | Total Turnovers | 46 | 1.00
4.56 | 125 | Penalties | 5 | 3.63
39.33 | 117 | Penalty Yards | 6 | 31.13

Drives & Special Teams

INDY Defense | Def. Rank | Stat | Off. Rank | PSU Offense
25:15 | 3 | Time on Field | 116 | 28:13
54.67 | 1 | Number of Plays | 113 | 63.25
4.54 | 14 | Yards Per Play | 98 | 5.31
5.56 | 14 | Punts | 27 | 2.88
44.28 | 111 | Punt Average | 20 | 46.38
51.78 | 81 | Return Yards | 60 | 60.88

All NFL Week 11 Predictions

UMass vs Akron Prediction and Pick, Week 11
Miami Ohio vs Ohio Prediction and Pick, Week 11
Northern Illinois vs Toledo Prediction and Pick, Week 11
Kent State vs Ball State Prediction and Pick, Week 11
UTSA vs South Florida Prediction and Pick, Week 11
Georgia Southern vs Appalachian State Prediction and Pick, Week 11
Houston vs UCF Prediction and Pick, Week 11
Tulane vs Memphis Prediction and Pick, Week 11
Northwestern vs USC Prediction and Pick, Week 11
Georgia vs Mississippi State Prediction and Pick, Week 11
BYU vs Texas Tech Prediction and Pick, Week 11
Colorado vs West Virginia Prediction and Pick, Week 11
James Madison vs Marshall Prediction and Pick, Week 11
SMU vs Boston College Prediction and Pick, Week 11
Temple vs Army Prediction and Pick, Week 11
Southern Miss vs Arkansas State Prediction and Pick, Week 11
Ohio State vs Purdue Prediction and Pick, Week 11
Bowling Green vs Eastern Michigan Prediction and Pick, Week 11
UAB vs Rice Prediction and Pick, Week 11
Maryland vs Rutgers Prediction and Pick, Week 11
Tulsa vs Florida Atlantic Prediction and Pick, Week 11
Charlotte vs East Carolina Prediction and Pick, Week 11
Louisiana Tech vs Delaware Prediction and Pick, Week 11
Florida International vs Middle Tennessee Prediction and Pick, Week 11
Jacksonville State vs UTEP Prediction and Pick, Week 11
Syracuse vs Miami Prediction and Pick, Week 11
Kansas vs Arizona Prediction and Pick, Week 11
Duke vs Connecticut Prediction and Pick, Week 11
Iowa State vs TCU Prediction and Pick, Week 11
Texas A&M vs Missouri Prediction and Pick, Week 11
Kennesaw State vs New Mexico State Prediction and Pick, Week 11
Georgia State vs Coastal Carolina Prediction and Pick, Week 11
Auburn vs Vanderbilt Prediction and Pick, Week 11
Stanford vs North Carolina Prediction and Pick, Week 11
Texas State vs Louisiana-Lafayette Prediction and Pick, Week 11
Air Force vs San Jose State Prediction and Pick, Week 11
Florida State vs Clemson Prediction and Pick, Week 11
California vs Louisville Prediction and Pick, Week 11
Wake Forest vs Virginia Prediction and Pick, Week 11
Nevada vs Utah State Prediction and Pick, Week 11
LSU vs Alabama Prediction and Pick, Week 11
Florida vs Kentucky Prediction and Pick, Week 11
Navy vs Notre Dame Prediction and Pick, Week 11
UNLV vs Colorado State Prediction and Pick, Week 11
Sam Houston vs Oregon State Prediction and Pick, Week 11
San Diego State vs Hawaii Prediction and Pick, Week 11
Indiana vs Penn State Prediction and Pick, Week 11
Washington vs Wisconsin Prediction and Pick, Week 11
Oregon vs Iowa Prediction and Pick, Week 11
Nebraska vs UCLA Prediction and Pick, Week 11

Visit the Betting School and learn how to wager on the moneyline, spread, and total; on your favorite team or an undervalued underdog. Sign up with YouWager.lv now and get in the game with the best welcome bonus, click below:

Indiana vs Penn State Prediction and Pick, Week 11, by YouWager.lv.