Colts at Chargers Prediction and Pick, Week 7
Colts at Chargers Prediction and Pick, Week 7. Place a bet on this NFL football game with the best odds.
Colts at Chargers Prediction: Indianapolis Trends
- The over/under record for Indianapolis’s previous six games is 4-2.
- In six of Indianapolis’ most recent nine games, the total has been higher than three.
- In its last seven games, Indianapolis has a winning record of 6-1 against the spread.
- Indianapolis has a record of 2-8-1 versus the Los Angeles Chargers in its last 11 games.
- When it comes to the Los Angeles Chargers, Indianapolis has a record of 1-5 on the road.
- In its previous five games played away from home, Indianapolis has a record of 1-4 against the spread.
- The Indianapolis Colts have a losing record of 1-4 on the road versus the Los Angeles Chargers in their last five games.
- Over the course of its last six games versus teams from the American Football Conference, Indianapolis has a perfect 6-0 record against those teams.
- Over the course of the last six games played in October, Indianapolis has a record of 5-1 against the spread.
- Four of the last six games that Indianapolis has played on a Sunday while they were away from home have resulted in the total going over.
Colts at Chargers Prediction: Los Angeles Trends
- Over the past 18 games, the Los Angeles Chargers have a record of 12-6 against the spread.
- In four of the last five games that the Los Angeles Chargers have played, the total has been under.
- Over the past ten games, the Los Angeles Chargers have a winning record of 7-3.
- In the last seven games that the Los Angeles Chargers have played versus Indianapolis, the total has been UNDER in five of those games.
- Six of the last eight games that the Los Angeles Chargers have played at home have resulted with the total going over.
- In its last five games versus Indianapolis, the Los Angeles Chargers have a winning record of 4-1 against the spread.
- LA Chargers is 7-1 SU in its last 8 games against an opponent in the American Football Conference conference.
- In ten of the last twelve games that the Los Angeles Chargers have played against teams that are members of the American Football Conference South division, the total has been above.
- After seven games, the Los Angeles Chargers have a record of 1-5 against the spread.
- In its last 13 games played on Sundays, the Los Angeles Chargers have a 9-4 overall record.
Colts at Chargers Prediction
Now we have the Colts at Chargers Prediction for both teams.
The Week 7 clash between the Indianapolis Colts and Los Angeles Chargers is shaping up to be one of the more intriguing matchups on the slate. Both teams enter this contest with plenty of offensive firepower and a growing sense of urgency as the season nears its midpoint. The Colts have been one of the league’s most efficient scoring teams, averaging an impressive 32.3 points per game, ranking first overall in the NFL. Their ability to move the ball both through the air and on the ground has been the key to their recent hot streak. Quarterback play has been sharp, the offensive line has kept him clean — allowing less than one sack per game — and the backfield continues to produce chunk gains. On the flip side, the Chargers have had a more uneven season, balancing solid defensive outings with frustrating offensive inconsistencies. While they’ve managed a few statement wins, they’ve also struggled to sustain drives and put up points against top-tier defenses — something that could haunt them against this well-balanced Colts team.
Statistically, the matchup presents a fascinating contrast. Indianapolis ranks top-10 in both passing and rushing offense, with over 245 passing yards and 131 rushing yards per game, while the Chargers’ defense sits middle of the pack against both. Los Angeles’ offense, though talented, has been less explosive than expected, posting just over 21 points per game while depending heavily on the passing attack. The Chargers’ offensive line has had trouble handling pressure, and that could become a major issue facing an Indy defense that ranks top-10 in sacks and turnovers forced. The Colts’ ability to control the tempo — with efficient scoring in nearly every quarter — makes them difficult to chase from behind. Combine that with their 6-1 record against the spread in their last seven and perfect 6-0 mark versus AFC opponents, and you have a team that’s playing with the confidence and consistency needed to win on the road.
Historically, the Chargers have had the upper hand in this series, but recent momentum clearly favors Indianapolis. The Colts’ recent dominance over AFC opponents, combined with their explosive offensive rhythm, makes them a legitimate threat to pull off the upset at SoFi Stadium. While Los Angeles tends to perform well at home and has covered in four of its last five versus Indy, the balance and resilience of this Colts squad shouldn’t be underestimated. The Chargers may keep things competitive early, but the Colts’ ability to finish strong — averaging nearly eight points in the fourth quarter — could prove decisive. Expect a fast-paced, high-scoring battle where Indianapolis’ offensive precision and turnover discipline make the difference.
Colts at Chargers Prediction: Head to Head
| Date | Opponent | Score | Spread | Total | Moneyline |
|---|---|---|---|---|---|
|
12/26/22
|
@IND
|
LAC 20-3
|
INDEVEN
|
U50.5
|
INDEVEN
|
|
9/08/19
|
@LAC
|
LAC 30-24
|
LAC-3.0
|
O47.5
|
LAC-165
|
Colts at Chargers Prediction: Indianapolis Last 10 Games
| Date | Opponent | Score | Spread | Total | Moneyline |
|---|---|---|---|---|---|
|
10/12/25
|
ARI
|
W 31-27
|
W+1.5
|
O47.5
|
W+102
|
|
10/05/25
|
LV
|
W 40-6
|
W-1.5
|
O44.5
|
W-122
|
|
9/28/25
|
@LAR
|
L 27-20
|
L+6.5
|
U48.5
|
L+230
|
|
9/21/25
|
@TEN
|
W 41-20
|
W+1.5
|
O45.5
|
W+102
|
|
9/14/25
|
DEN
|
W 29-28
|
W+3.5
|
O44.5
|
W+145
|
|
9/07/25
|
MIA
|
W 33-8
|
W-1.5
|
U45.5
|
W-116
|
|
1/05/25
|
JAC
|
W 26-23
|
W-1.5
|
O46.5
|
W-122
|
|
12/29/24
|
@NYG
|
L 45-33
|
L-2.0
|
O43.5
|
L-130
|
|
12/22/24
|
TEN
|
W 38-30
|
W-4.0
|
O44.5
|
W-175
|
|
12/15/24
|
@DEN
|
L 31-13
|
L-2.5
|
O42.5
|
L-142
|
Colts at Chargers Prediction: Los Angeles Last 10 Games
| Date | Opponent | Score | Spread | Total | Moneyline |
|---|---|---|---|---|---|
|
10/12/25
|
@MIA
|
W 29-27
|
W-1.5
|
O45.5
|
W-122
|
|
10/05/25
|
WAS
|
L 27-10
|
L-1.5
|
U47.5
|
L-122
|
|
9/28/25
|
@NYG
|
L 21-18
|
L-3.5
|
U43.5
|
L-175
|
|
9/21/25
|
DEN
|
W 23-20
|
W-1.5
|
U44.5
|
W-120
|
|
9/15/25
|
@LV
|
W 20-9
|
W-3.0
|
U44.5
|
W-155
|
|
9/05/25
|
KC
|
W 27-21
|
W+3.0
|
O45.5
|
W+122
|
|
1/11/25
|
@HOU
|
L 32-12
|
L-2.5
|
O43.5
|
L-148
|
|
1/05/25
|
@LV
|
W 34-20
|
W-1.0
|
O44.5
|
W-122
|
|
12/28/24
|
@NE
|
W 40-7
|
W-5.0
|
O41
|
W-135
|
|
12/19/24
|
DEN
|
W 34-27
|
W-3.5
|
O45
|
W-180
|
Colts at Chargers Prediction: Indianapolis Offense
Overall
| IND Offense | Off. Rank | Stat | Def. Rank | LAC Defense |
|---|---|---|---|---|
| 32.33 | 1 | Points Scored | 12 | 20.83 |
| 245.00 | 5 | Passing Yards | 6 | 177.50 |
| 131.83 | 6 | Rushing Yards | 21 | 124.17 |
| 30:22 | 19 | Time on Field | 5 | 28:14 |
| 60.17 | 19 | Number of Plays | 10 | 58.50 |
| 6.26 | 2 | Yards Per Play | 9 | 5.16 |
Scoring
| IND Offense | Off. Rank | Stat | Def. Rank | LAC Defense |
|---|---|---|---|---|
| 32.33 | 1 | Points Scored | 12 | 20.83 |
| 6.00 | 7 | First Quarter | 4 | 2.83 |
| 11.33 | 2 | Second Quarter | 18 | 6.33 |
| 7.17 | 3 | Third Quarter | 26 | 5.67 |
| 7.83 | 10 | Fourth Quarter | 12 | 6.00 |
Passing
| IND Offense | Off. Rank | Stat | Def. Rank | LAC Defense |
|---|---|---|---|---|
| 245.00 | 5 | Passing Yards | 6 | 177.50 |
| 30.50 | 21 | Pass Attempts | 14 | 31.17 |
| 21.67 | 14 | Pass Completions | 7 | 18.83 |
| 0.83 | 1 | Sacks | 8 | 2.67 |
| 6.83 | 30 | Sack Yards | 17 | 14.83 |
| 11.31 | 5 | Yards Per Pass | 8 | 9.42 |
Rushing
| IND Offense | Off. Rank | Stat | Def. Rank | LAC Defense |
|---|---|---|---|---|
| 131.83 | 6 | Rushing Yards | 21 | 124.17 |
| 28.83 | 6 | Rush Attempts | 14 | 24.67 |
| 4.57 | 13 | Yards Per Rush | 28 | 5.03 |
Turn Overs
| IND Offense | Off. Rank | Stat | Def. Rank | LAC Defense |
|---|---|---|---|---|
| 0.50 | 13 | Interceptions | 8 | 1.00 |
| 0.50 | 6 | Fumbles | 20 | 0.83 |
| 0.17 | 4 | Fumbles Lost | 28 | 0.17 |
| 0.67 | 8 | Total Turnovers | 14 | 1.17 |
| 7.33 | 18 | Penalties | 15 | 7.33 |
| 56.83 | 16 | Penalty Yards | 17 | 57.33 |
Drives & Special Teams
| IND Offense | Off. Rank | Stat | Def. Rank | LAC Defense |
|---|---|---|---|---|
| 30:22 | 19 | Time on Field | 5 | 28:14 |
| 60.17 | 19 | Number of Plays | 10 | 58.50 |
| 6.26 | 2 | Yards Per Play | 9 | 5.16 |
| 1.67 | 1 | Punts | 16 | 3.50 |
| 52.12 | 3 | Punt Average | 16 | 48.37 |
| 115.83 | 23 | Return Yards | 30 | 158.50 |
Colts at Chargers Prediction: Los Angeles Offense
Overall
| IND Defense | Def. Rank | Stat | Off. Rank | LAC Offense |
|---|---|---|---|---|
| 19.33 | 4 | Points Scored | 23 | 21.17 |
| 232.83 | 22 | Passing Yards | 10 | 240.00 |
| 96.33 | 12 | Rushing Yards | 13 | 120.67 |
| 29:37 | 16 | Time on Field | 7 | 31:45 |
| 61.67 | 21 | Number of Plays | 10 | 63.67 |
| 5.34 | 15 | Yards Per Play | 12 | 5.66 |
Scoring
| IND Defense | Def. Rank | Stat | Off. Rank | LAC Offense |
|---|---|---|---|---|
| 19.33 | 4 | Points Scored | 23 | 21.17 |
| 3.83 | 9 | First Quarter | 8 | 6.00 |
| 5.00 | 8 | Second Quarter | 24 | 5.50 |
| 4.67 | 18 | Third Quarter | 8 | 5.83 |
| 5.83 | 10 | Fourth Quarter | 31 | 3.83 |
Passing
| IND Defense | Def. Rank | Stat | Off. Rank | LAC Offense |
|---|---|---|---|---|
| 232.83 | 22 | Passing Yards | 10 | 240.00 |
| 36.67 | 26 | Pass Attempts | 4 | 36.67 |
| 24.17 | 25 | Pass Completions | 3 | 24.83 |
| 2.67 | 7 | Sacks | 25 | 3.00 |
| 16.17 | 21 | Sack Yards | 9 | 16.17 |
| 9.63 | 11 | Yards Per Pass | 20 | 9.66 |
Rushing
| IND Defense | Def. Rank | Stat | Off. Rank | LAC Offense |
|---|---|---|---|---|
| 96.33 | 12 | Rushing Yards | 13 | 120.67 |
| 22.33 | 3 | Rush Attempts | 26 | 24.00 |
| 4.31 | 19 | Yards Per Rush | 3 | 5.03 |
Turn Overs
| IND Defense | Def. Rank | Stat | Off. Rank | LAC Offense |
|---|---|---|---|---|
| 1.17 | 3 | Interceptions | 20 | 0.67 |
| 0.33 | 30 | Fumbles | 27 | 1.33 |
| 0.33 | 20 | Fumbles Lost | 25 | 0.67 |
| 1.50 | 7 | Total Turnovers | 21 | 1.33 |
| 6.50 | 21 | Penalties | 21 | 7.67 |
| 59.83 | 13 | Penalty Yards | 18 | 57.33 |
Drives & Special Teams
| IND Defense | Def. Rank | Stat | Off. Rank | LAC Offense |
|---|---|---|---|---|
| 29:37 | 16 | Time on Field | 7 | 31:45 |
| 61.67 | 21 | Number of Plays | 10 | 63.67 |
| 5.34 | 15 | Yards Per Play | 12 | 5.66 |
| 2.17 | 31 | Punts | 9 | 3.17 |
| 43.18 | 1 | Punt Average | 7 | 49.85 |
| 136.33 | 16 | Return Yards | 24 | 115.00 |
✅ Our NFL Week 7 Pick: Indianapolis Colts ML
All NFL Week 7 Predictions
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Colts at Chargers Prediction and Pick, Week 7, by YouWager.lv.