Atlanta Falcons vs Arizona Cardinals Prediction and Pick, Week 16, NFL Betting Picks

Atlanta Falcons vs Arizona Cardinals Prediction and Pick, Week 16, NFL Betting Picks. Place a bet on this game with the best odds.

Atlanta Falcons vs Arizona Cardinals Prediction – NFL Betting Picks

Now we have the Atlanta Falcons vs Arizona Cardinals Prediction for both teams.

After suffering defeat in each of their previous six games in a row, Arizona approaches this match with the intention of turning things around. Despite quarterback Jacoby Brissett’s impressive performance, the Cardinals were defeated by Houston by a score of 40-20 in their most recent game. Brissett completed 27 of 40 passes for 277 yards, threw three touchdown passes, and threw one interception. A total of 2,708 throwing yards have been accumulated by Brissett throughout the course of this season. The contributions of Arizona’s running backs Bam Knight, who has ran for 269 yards, and Emari Demercado, who has contributed 242 yards of his own, have been significant. With an incredible 1,071 receiving yards so far this season, tight end Trey McBride has established himself as a vital target in the passing game. He has led the team in receiving yards accumulated. It is unfortunate that the Cardinals’ defense has been struggling, particularly in recent times. In the five games that they have played recently, they have allowed an average of 34.8 points per game, and they have had a difficult time winning at home, with only one victory coming in Glendale throughout the entire season. The Arizona Cardinals are desperate to end their current losing run and are trying to secure a victory over the Falcons in front of their home fans by pulling off an unexpected triumph.

Atlanta enters this clash riding the adrenaline of a recent triumph, having defeated Tampa Bay in a nail-biting 29-28 victory. The game is expected to be full of excitement. That victory put an end to a difficult stretch for the Falcons, who had been losing three of their previous five games up to that point. By completing 30 of his 44 throws and finding the end zone three times through the air, quarterback Kirk Cousins was a significant contributor to the victory (which was by the skin of his teeth). Cousins has put up 1,218 passing yards throughout the course of this season, which is a testament to the fact that he has been playing under center consistently. There has been a remarkable total of 1,174 running yards recorded by Bijan Robinson so far, demonstrating that he continues to be a driving force for Atlanta’s attack. Among the wideouts, Drake London has the most receiving yards with 810, and tight end Kyle Pitts Jr. is not far behind him with 797 receiving yards. Both of these players have contributed to the receiving game this season. Over the course of their most recent five games, the Falcons have allowed an average of 26.4 points per game, which indicates that their defensive unit has been experiencing a good amount of difficulty. They are hopeful that their big win in Tampa Bay will serve as a turning point as they travel the road once more, and this time they are seeking to transfer that enthusiasm and confidence into Arizona. Despite these hurdles, Atlanta is expecting that their big win will serve as a turning point.

Up to this point in the season, the Cardinals have had a difficult time, particularly while playing in front of their own fans at State Farm Stadium, where they have only managed to win one of their last seven games. When they play the Falcons in Glendale, they will be ready to finish off that slump and give their fans something to celebrate about. They will also be keen to give their fans something to cheer about. On the other hand, Atlanta is coming off of a hard-fought victory away from home against the Buccaneers. This victory might provide them with a much-needed boost as they prepare for their next game, which will take place in Arizona. Prediction of the Final Score for the Arizona Cardinals…

✅ Our Atlanta Falcons vs Arizona Cardinals Pick:

Atlanta Falcons vs Arizona Cardinals Trends

Six of Atlanta’s most recent seven games have resulted in the total going over.
In its last nine games, Atlanta has a winning percentage of 2-7.
In its last 15 games versus Arizona, Atlanta has a consistent record of 10-5.
In four of Atlanta’s most recent five games played away from home, the total has been above.
When playing Arizona away from home, Atlanta has a losing record of 0-5 single-score in its last five games.
When Atlanta has played an opponent from the National Football Conference, the total has gone over in four of the last six games that Atlanta has played against that opponent.
Against the spread, Atlanta has a record of 0-5 in its previous five games against teams that are members of the National Football Conference West division.
In its last 15 games played in December, Atlanta has a winning percentage of 5-10.
Over the past six games, Arizona has a record of 1-5 against the spread.
In five of Arizona’s most recent six games, the total has been taken over.
In its last six games, Arizona has a losing record of 0-6 against the spread.
In five of Arizona’s last six games versus Atlanta, the total has been higher than the point spread.
5 of Arizona’s most recent 5 games played at home have resulted in the total going over.
As a result of playing at home versus Atlanta, Arizona has a perfect record of 5-0 in its past five games.
Seven of Arizona’s eight most recent games against opponents from the National Football Conference have resulted in a loss for the Arizona Wildcats.
During its most recent nine games versus teams from the National Football Conference South division, Arizona had a record of 7-2 against the spread.
Out of the five games that Arizona has played in December, the total has been over in four of those games.
On the road, Arizona has a record of 1-4 in its last five games played in week 16.

Atlanta Falcons vs Arizona Cardinals Odds

Now, we have the Atlanta Falcons vs Arizona Cardinals odds:

TEAM	SPREAD	MONEYLINE	TOTAL
Falcons	+1.5	+125	48 O
Cardinals	-1.5	-105	48 U

Atlanta Falcons vs Arizona Cardinals Prediction: Head to Head

Date	Team	Opp	Close	Result	ATS/OU
Nov 12, 2023	Cardinals	Falcons	+2 / 43.5	Won 25-23	Won / Over
Jan 1, 2023	Cardinals	@Falcons	+6.5 / 40.5	Lost 19-20	Won / Under
Oct 13, 2019	Cardinals	Falcons	+3 / 52.5	Won 34-33	Won / Over
Dec 16, 2018	Cardinals	@Falcons	+10 / 43.5	Lost 14-40	Lost / Over
Aug 26, 2017	Cardinals	@Falcons	+3.5 / 42.5	Won 24-14	Won / Under
Nov 27, 2016	Cardinals	Falcons	-3.5 / 49	Lost 0-0	Lost / Under
Nov 30, 2014	Cardinals	Falcons	+1.5 / 45.5	Lost 0-0	Won / Under
Oct 27, 2013	Cardinals	@Falcons	+2.5 / 44.5	Lost 0-0	Won / Under
Nov 18, 2012	Cardinals	Falcons	-9.5 / 43	Lost 0-0	Lost / Under
Sep 19, 2010	Cardinals	Falcons	-7 / 43	Lost 0-0	Lost / Under

Atlanta Falcons vs Arizona Cardinals Prediction: Falcons Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
12/11/25	@TB	W 29-28	W+5.5	O47.5	W+185
12/07/25	SEA	L 37-9	L-1.5	O45.5	L-120
11/30/25	@NYJ	L 27-24	L-1.5	O43.5	L-120
11/23/25	@NO	W 24-10	W-2.5	U44	W-125
11/16/25	CAR	L 30-27	L-3.0	O45.5	L-155
11/09/25	@IND	L 31-25	L-1.5	O44.5	L-118
11/02/25	@NE	L 24-23	W+3.0	O44.5	L+136
10/26/25	MIA	L 34-10	L-1.5	U46.5	L-120
10/19/25	@SF	L 20-10	L+6.5	U47.5	L+225
10/13/25	BUF	W 24-14	W+5.5	U48.5	W+185

Atlanta Falcons vs Arizona Cardinals Prediction: Cardinals Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
12/14/25	@HOU	L 40-20	L+2.5	O45.5	L+110
12/07/25	LAR	L 45-17	L+1.5	O47.5	L-102
11/30/25	@TB	L 20-17	W+3.5	U48.5	L+150
11/23/25	JAC	L 27-24	L-3.0	O47.5	L-155
11/16/25	SF	L 41-22	L+1.5	O47.5	LEVEN
11/09/25	@SEA	L 44-22	L+1.5	O44.5	LEVEN
11/03/25	@DAL	W 27-17	W+1.5	U52.5	W+102
10/19/25	GB	L 27-23	L+1.5	O47.5	LEVEN
10/12/25	@IND	L 31-27	L-1.5	O47.5	L-122
10/05/25	TEN	L 22-21	L-5.5	U46.5	L-225

Atlanta Falcons vs Arizona Cardinals Prediction: Falcons Offense

Overall

ATL Offense	Off. Rank	Stat	Def. Rank	ARI Defense
20.07	26	Points Scored	27	27.71
217.71	16	Passing Yards	21	226.57
122.71	12	Rushing Yards	21	124.50
29:42	20	Time on Field	9	29:20
61.50	16	Number of Plays	21	62.29
5.54	11	Yards Per Play	24	5.64

Scoring

ATL Offense	Off. Rank	Stat	Def. Rank	ARI Defense
20.07	26	Points Scored	27	27.71
4.57	16	First Quarter	29	6.29
6.50	20	Second Quarter	21	7.71
2.86	28	Third Quarter	17	4.79
6.14	20	Fourth Quarter	28	8.71

Passing

ATL Offense	Off. Rank	Stat	Def. Rank	ARI Defense
217.71	16	Passing Yards	21	226.57
32.71	15	Pass Attempts	18	32.93
20.00	19	Pass Completions	21	21.57
1.50	4	Sacks	27	1.79
10.86	28	Sack Yards	8	12.21
10.89	10	Yards Per Pass	22	10.50

Rushing

ATL Offense	Off. Rank	Stat	Def. Rank	ARI Defense
122.71	12	Rushing Yards	21	124.50
27.29	16	Rush Attempts	20	27.57
4.50	11	Yards Per Rush	25	4.52

Turn Overs

ATL Offense	Off. Rank	Stat	Def. Rank	ARI Defense
0.43	3	Interceptions	17	0.64
1.29	27	Fumbles	5	1.21
0.64	26	Fumbles Lost	6	0.57
1.07	12	Total Turnovers	11	1.21
6.57	14	Penalties	25	6.00
51.07	15	Penalty Yards	15	53.14

Drives & Special Teams

ATL Offense	Off. Rank	Stat	Def. Rank	ARI Defense
29:42	20	Time on Field	9	29:20
61.50	16	Number of Plays	21	62.29
5.54	11	Yards Per Play	24	5.64
3.93	24	Punts	31	2.71
43.89	30	Punt Average	31	49.50
110.50	27	Return Yards	16	129.00

Atlanta Falcons vs Arizona Cardinals Prediction: Cardinals Offense