Chargers vs Giants Betting Prediction Week 4, 2025

Chargers vs Giants Betting Prediction Week 4, 2025. Place a bet on this NFL football game with the best odds.

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The Week 4 matchup between the Los Angeles Chargers and New York Giants presents one of the more intriguing betting opportunities of the early season.

Chargers vs Giants Betting Prediction

From a betting perspective, all signs point toward Los Angeles continuing its dominance in this series. The Chargers’ defense has been one of the league’s most reliable, ranking fourth in points allowed while keeping opposing quarterbacks in check. Matchups against AFC opponents have typically gone under for both teams, but head-to-head history suggests the over is also in play when these squads meet. Bettors should keep an eye on the Chargers’ ability to establish a lead early, as they’ve been one of the strongest first-quarter teams in football. Meanwhile, the Giants will need a near-perfect performance to pull off an upset at home, but given their defensive vulnerabilities, Los Angeles holds a clear edge in both momentum and execution heading into this Week 4 clash.

Chargers vs Giants Betting Prediction: Head to Head

Date	Team	Opp	Close	Result	ATS/OU
Dec 12, 2021	Chargers	Giants	-9 / 43.5	Won 37-21	Won / Over
Oct 8, 2017	Chargers	@Giants	+3 / 45.5	Won 27-22	Won / Over
Dec 8, 2013	Chargers	@Giants	+4.5 / 46.5	Lost 0-0	Won / Under
Nov 8, 2009	Chargers	Giants	-5 / 48.5	Lost 0-0	Lost / Under
Sep 25, 2005	Chargers	@Giants	+6.5 / 43	Lost 0-0	Won / Under

Chargers vs Giants Betting Prediction: Los Angeles

Los Angeles enters the contest with strong momentum, boasting a 3-0 start to 2025 and a recent track record of success both straight up and against the spread. Their offense has been fueled by an efficient passing attack that ranks second in the league at 270 yards per game. While the run game has lacked consistency, the Chargers have balanced this weakness with time of possession dominance and disciplined play, averaging just one turnover per game. Historically, Los Angeles has owned this head-to-head matchup, going 5-0 ATS in the last five meetings against the Giants.

Chargers vs Giants Betting Prediction: Los Angeles Trends

• Over the past seven games, the Los Angeles Chargers have a record of 6-1 against the spread.
• In six of the previous eight games that the Los Angeles Chargers have played, the total has been higher than the point spread.
• The Los Angeles Chargers have a winning record of 6-1 in their previous seven games.
• Versus the spread, the Los Angeles Chargers have a perfect record of 5-0 in their last five games versus the New York Giants.
• The Los Angeles Chargers have a perfect record of 5-0 in their previous five games versus the New York Giants.
• The Los Angeles Chargers have a record of 4-1 against the spread in their last five games played away from home.
• On the road against the New York Giants, the Los Angeles Chargers have a winning record of 4-1 in their last five games.
• Over the course of the last six games that the Los Angeles Chargers have played against teams from the National Football Conference, the total has been under in five of those games.
• The Los Angeles Chargers have a winning record of 14-4 in their previous 18 games versus teams that are members of the National Football Conference East division.
• In seven of the eight games that the Los Angeles Chargers have played in September, the total has been under.

Los Angeles Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
9/21/25	DEN	W 23-20	W-1.5	U44.5	W-120
9/15/25	@LV	W 20-9	W-3.0	U44.5	W-155
9/05/25	KC	W 27-21	W+3.0	O45.5	W+122
1/11/25	@HOU	L 32-12	L-2.5	O43.5	L-148
1/05/25	@LV	W 34-20	W-1.0	O44.5	W-122
12/28/24	@NE	W 40-7	W-2.5	O41	W-135
12/19/24	DEN	W 34-27	W-3.5	O45	W-180
12/15/24	TB	L 40-17	L-3.0	O42.5	L-148
12/08/24	@KC	L 19-17	W+6.5	U44.5	L+215
12/01/24	@ATL	W 17-13	W+2.5	U47.5	W+114

Chargers vs Giants Betting Prediction: Los Angeles Offense

Chargers vs Giants Betting Prediction: New York

On the other side, the New York Giants are searching for stability after a rough start to the season. Their offense has leaned on the passing game, currently ranked ninth in yards, but struggles to finish drives consistently. Scoring just 17.3 points per game, New York has failed to complement their aerial production with a reliable run game or red-zone efficiency. Defensively, the Giants have been overmatched, giving up nearly 28 points per contest while ranking near the bottom of the league in both rushing and passing yards allowed. Betting trends have been even worse, with the Giants going 3-12 ATS in their last 15 games and just 1-9 ATS in their last ten home contests.

Chargers vs Giants Betting Prediction: New York Trends

• Over the past 15 games, the New York Giants have a record of 3-12 against the spread.
• In four of the last six games that the New York Giants have played, the total has been under.
• In their last 15 games, the New York Giants have a record of 1-14 on the road.
• In six of the last seven games that the New York Giants have played against the Los Angeles Chargers, the total has been over.
• In their previous ten games played at home, the New York Giants have a record of 1-9 against the spread.
• In their last five games against the Los Angeles Chargers, the New York Giants have a record of 1-4 on the road.
• When playing against teams from the American Football Conference, the New York Giants have a record of 1-4 against the spread in their last five games.
• There have been eight of the nine games that the New York Giants have played against opponents from the American Football Conference West division in which the total has been UNDER.
• In seven of the last eight games that the New York Giants have played in September, the total has been under.
• The New York Giants have a record of 5-1 against the spread in their previous six games played in week 4.

New York Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
9/21/25	KC	L 22-9	L+6.5	U43.5	L+230
9/14/25	@DAL	L 40-37	W+4.5	O44.5	L+154
9/07/25	@WAS	L 21-6	L+7.0	U45.5	L+280
1/05/25	@PHI	L 20-13	L+5.0	U44.5	L+180
12/29/24	IND	W 45-33	W+2.0	O43.5	W+110
12/22/24	@ATL	L 34-7	L+4.5	U44.5	L+164
12/15/24	BAL	L 35-14	L+6.5	O44	L+225
12/08/24	NO	L 14-11	L+0.5	U41	L-108
11/28/24	@DAL	L 27-20	W+9.5	O46.5	L+345
11/24/24	TB	L 30-7	L+1.0	U44	L-105

Chargers vs Giants Betting Prediction: New York Offense

 

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