Eagles vs Chiefs Prediction NFL Week 2 Predictions. Place a bet on this NFL football game with the best lines and bonuses at YouWager.lv.

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The Philadelphia Eagles and Kansas City Chiefs meet in a highly anticipated Week 2 clash that serves as a rematch of last season’s Super Bowl.

Eagles vs Chiefs Prediction NFL Week 2 Predictions

The Philadelphia Eagles defeated the Kansas City Chiefs 40-22 in Super Bowl LIX. The two teams will face off again on Sunday, September 14th, at GEHA Field at Arrowhead Stadium, this time in a rematch of the previous Super Bowl.

The game has began with the Kansas City Chiefs as 1.5-point underdogs, according to YouWager Sportsbook.

The Chiefs were favored to win by three points when they took on the Los Angeles Chargers in the first week of the season, but they ended up losing 27–21. With a 24-21 victory against the Dallas Cowboys in the league’s first game, the Eagles are carrying a winning streak into the next match.

Beginning their season with a defeat is not something that the Chiefs are familiar with. The squad has only been defeated three times in the first week under Andy Reid’s leadership as head coach, and Friday was the most recent of those losses.

There will be two Super Bowl MVPs playing quarterback positions in the game. Each of them have one victory in the regular season and one victory in the Super Bowl against the other, and each of them has a record of two wins and two losses. It would appear as though Sunday will be the next thrilling chapter in the rivalry.

Eagles vs Chiefs Prediction NFL Week 2 Predictions: Head to Head

Date	Opponent	Score	Spread	Total	Moneyline
2/09/25	@PHI	PHI 40-22	PHI+1.5	O49.5	PHI+110
11/20/23	@KC	PHI 21-17	KC-3.5	U50.5	KC-186
2/12/23	@PHI	KC 38-35	PHI-1.5	O49.5	PHI-132
10/03/21	@PHI	KC 42-30	PHI+7.0	O54.5	PHI+260
9/17/17	@KC	KC 27-20	NL	NL	NL
9/19/13	@PHI	KC 26-16	NL	NL	NL
9/27/09	@PHI	PHI 34-14	NL	NL	NL
10/02/05	@KC	PHI 37-31	NL	NL	NL

Eagles vs Chiefs Prediction NFL Week 2 Predictions: Team Previews

From a betting perspective, this game offers fascinating angles. The Eagles have been excellent against the spread on the road, going 5-1 in their last six, while also dominating recent matchups against AFC opponents. Kansas City, however, has thrived at home and holds a 16-4 record in their last 20 games overall. Both offenses are capable of big scoring bursts, and trends point to the over being a strong possibility, especially given the history between these teams. With two elite quarterbacks, strong coaching staffs, and playoff-level stakes this early in the season, Week 2’s Eagles vs. Chiefs matchup has all the makings of another classic.

Eagles vs Chiefs Prediction NFL Week 2 Predictions: Philadelphia

Now in this Eagles vs Chiefs Prediction NFL Week 2 Predictions, we have the Philadelphia betting preview.

Philadelphia enters this contest riding high, fresh off a dramatic opening-week victory over the Dallas Cowboys and still carrying the confidence of their 40-22 Super Bowl triumph over Kansas City. Jalen Hurts continues to grow as a leader, showing poise and efficiency while backed by one of the most complete rosters in football. The Eagles’ defensive front, known for creating chaos, will again be tasked with pressuring Patrick Mahomes and limiting explosive plays from the Chiefs’ offense.

Eagles vs Chiefs Prediction NFL Week 2 Predictions: Philadelphia Trends

Next in this Eagles vs Chiefs Prediction NFL Week 2 Predictions, we have the Philadelphia trends:

• The Philadelphia team has won 10 and lost 4 of their previous 14 games when taking into account the point spread.
• The Philadelphia team has a record of 7 wins and 0 losses in their past seven games, with a straight up (SU) result.
• In its last six matchups versus Kansas City, Philadelphia has had an ATS record of 2 wins and 4 losses.
• In their last six matchups, Philadelphia has a straight-up record of 2–4 against Kansas City.
• The Philadelphia team has a record of 5–1 against the spread in their previous six away games.
• In the past six games that Philadelphia has played versus Kansas City on the road, the score has been 4–2 SU.
• In the last nine games that the Philadelphia Eagles have played against an opponent in the American Football Conference, they have achieved a record of 9 wins and 0 losses.
• The total has gone OVER in 10 out of the previous 13 games that Philadelphia has played against a team in the American Football Conference West division.
• The total has gone under in four of the six most recent games played by Philadelphia in September.

Philadelphia Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
9/04/25	DAL	W 24-20	L-6.5	U46.5	W-310
2/09/25	KC	W 40-22	W+1.5	O49.5	W+110
1/26/25	WAS	W 55-23	W-4.5	O47.5	W-225
1/19/25	LAR	W 28-22	W-5.5	O44.5	W-240
1/12/25	GB	W 22-10	W-3.5	U46.5	W-198
1/05/25	NYG	W 20-13	W-5.0	U44.5	W-218
12/29/24	DAL	W 41-7	W-2.0	O47	W-135
12/22/24	@WAS	L 36-33	L-2.5	O46.5	L-135
12/15/24	PIT	W 27-13	W-3.0	U45	W-148
12/08/24	CAR	W 22-16	L-7.0	U45	W-310

Eagles vs Chiefs Prediction NFL Week 2 Predictions: Kansas City

Now in this Eagles vs Chiefs Prediction NFL Week 2 Predictions, we have the Kansas City betting preview.

Kansas City, on the other hand, finds itself in rare territory after beginning the season with a loss. Under Andy Reid, the Chiefs have been one of the most consistent teams in the league, but their Week 1 stumble against the Chargers exposed defensive concerns and left Mahomes carrying much of the burden. The good news for Kansas City is their dominance at Arrowhead Stadium, where they have won 13 straight games, and the fact that Mahomes rarely stays down for long. With a revenge game narrative and the home crowd behind them, the Chiefs remain a dangerous opponent despite entering as slight underdogs.

Eagles vs Chiefs Prediction NFL Week 2 Predictions: Kansas City Trends

Next in this Eagles vs Chiefs Prediction NFL Week 2 Predictions, we have the Kansas City trends:

• The current record of Kansas City is 1–4 against the spread in the previous five games played.
• Over the course of their most recent 20 games, the Kansas City team has had a record of 16 wins and 4 losses.
• The total has gone OVER in four out of the last five matches between Philadelphia and Kansas City.
• Over the course of their most recent thirteen home games, Kansas City has a winning record of 13–0.
• When playing at home versus Philadelphia, Kansas City has an SU record of 2–4 in its last six games.
• In their most recent 19 games versus an opponent in the National Football Conference conference, Kansas City has a record of 13–6 against the spread.
• In the past nine contests, the total score for Kansas City has come in under six times against an opponent in the National Football Conference East division.
• Out of the last six games that Kansas City has played in the month of September, the total has gone over four times.
• Over the course of the last six games that Kansas City has played in week two, the team has had an ATS record of 2–4.

Kansas City Last 10 Games

Date	Opponent	Score	Spread	Total	Moneyline
9/05/25	@LAC	L 27-21	L-3.0	O45.5	L-144
2/09/25	@PHI	L 40-22	L-1.5	O49.5	L-130
1/26/25	BUF	W 32-29	W-1.5	O48.5	W-120
1/18/25	HOU	W 23-14	W-8.0	U42	W-480
1/05/25	@DEN	L 38-0	L-4.0	U46.5	L-192
12/25/24	@PIT	W 29-10	W-4.0	U41.5	W-290
12/21/24	HOU	W 27-19	W-4.5	U47	W-205
12/15/24	@CLE	W 21-7	W-3.0	U46.5	W-142
12/08/24	LAC	W 19-17	L-6.5	U44.5	W-265
11/29/24	LV	W 19-17	L-7.0	U45.5	W-340

 

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