Steelers vs Panthers Preseason Betting Prediction Week 3 August 21. Place a bet on this NFL football game with the best odds.

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Steelers vs Panthers Preseason Betting Prediction

The Steelers and Panthers meet in Week 3 of the 2025 NFL preseason in a matchup that carries plenty of betting intrigue. From a totals perspective, trends point toward a higher-scoring contest. The OVER has cashed in five of the Panthers’ last six games, as their defensive lapses force shootouts regardless of the opponent. The Steelers, however, have leaned UNDER in several NFC matchups, creating an interesting clash of betting tendencies. While preseason outcomes can be unpredictable with rotations and backups seeing heavy snaps, the matchup edges still favor Pittsburgh. Their ability to run the football efficiently against the league’s worst run defense, combined with Carolina’s struggles both in August and against AFC teams, makes the Steelers the stronger play. Bettors should keep a close eye on line movement leading up to kickoff, but all signs suggest Pittsburgh has the advantage to cover and push this game toward another OVER result.

Steelers vs Panthers Preseason Betting Prediction: Head to Head

Steelers vs Panthers Preseason Betting Prediction: Pittsburgh

Pittsburgh has long held the upper hand in this series, owning a 13-6 head-to-head record across the last 19 meetings, including a 24-16 win in their most recent clash back in 2022. The Steelers enter this game with some clear betting patterns: they’ve struggled against the spread recently (2-5 ATS in their last seven), but they’ve historically performed well against NFC South opponents with a dominant 7-1 ATS record in their last eight. Their offense leans heavily on the ground game, ranking 12th in rushing, and with Carolina’s defense ranking dead last against the run, bettors may expect Pittsburgh’s running backs to have a field day in this preseason matchup.

Steelers vs Panthers Preseason Betting Prediction: Pittsburgh Trends

• Over the past seven games, Pittsburgh has a record of 2-5 against the spread.
• In four of Pittsburgh’s most recent five games, the total has been reported as UNDER.
• In its previous seven games, Pittsburgh has a record of 1-6 against the spread.
• After six games versus Carolina, Pittsburgh has a record of 4-2 against the spread.
• In its last 19 games versus Carolina, Pittsburgh has a head-to-head record of 13-6.
• In seven of Pittsburgh’s most recent nine games played away from home, the total has been over.
• As a result of playing away against Carolina, Pittsburgh has a record of 8-4 against the spread in its last 12 games.
• There have been four out of the last six games that Pittsburgh has played against an opponent from the National Football Conference that have ended with the total at UNDER.
• Over the course of its last eight games against teams from the National Football Conference South division, Pittsburgh has a record of 7-1 against the spread.
• Over the course of the month of August, Pittsburgh has a record of 1-4 on the road.

Steelers vs Panthers Preseason Betting Prediction: Carolina

Carolina, on the other hand, continues to battle a reputation as one of the least reliable betting options in recent years. The Panthers come into this game with a 2-7 ATS record in their last nine games overall and a dismal 0-6 run against AFC North teams. Their defense was historically poor last season, ranking last in both points allowed (31.41 per game) and rushing yards allowed (179.82 per game). Preseason or not, these weaknesses are difficult to ignore, especially against a Steelers team that thrives on physicality and punishing the trenches. Adding to their woes, Carolina has struggled badly in August, going winless in their last six preseason games that month, making it hard for bettors to put trust in them even with a home-field advantage.

Steelers vs Panthers Preseason Betting Prediction: Carolina Trends

• In its last six games, Carolina has a 2–4 overall record.
• In five of Carolina’s most recent six games, the total has been taken over.
• In their last nine games, Carolina has a record of 2-7 against the spread.
• 5 of the previous 5 games that Carolina has played versus Pittsburgh have resulted in the total going over.
• This is the fifth time in Carolina’s last five home games that the total has gone over.
• When playing at home versus Pittsburgh, Carolina has a record of 4-8 against the spread in its last 12 games.
• When it comes to its most recent five games versus opponents from the American Football Conference, Carolina has a losing record of 0-5 for the season.
• In its last six games against teams from the American Football Conference North division, Carolina has a record of 0-6 in terms of its overall performance.
• In its last six games played in August, Carolina has a head-to-head record of 0-6.
• In five of Carolina’s most recent five games that have been played on Thursdays, the total has been under.

 

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